COVID-19

COVID-19 Resources: CIHR-led and CIHR-funded COVID-19 resources and research outputs

CIHR-led COVID-19 resources to support research and clinical trials

• Why sex and gender need to be considered in COVID-19 research: A guide for applicants and reviewers offers guidance from CIHR on how to integrate sex, gender and other identity factors in COVID-19 research
• The Linkage Tool for the COVID-19 Rapid Response Funding is a database of researchers, individuals, and organizations who are interested in sharing data or collaborating in COVID-19 research

CIHR-funded COVID-19 initiatives, resources and outputs

• SPOR COVID-19 related activity: Overview of work - June 2020
• The SPOR Evidence Alliance has completed two rapid reviews (pre-prints) to inform the World Health Organization guidance document on infection prevention and control for long-term care facilities [ PDF (613 KB) - external link ]
  • Preventing respiratory illness in older adults aged 60 years and above living in long-term care
  • Guidelines for preventing respiratory illness in older adults aged 60 years and above living in long-term care: A rapid review of clinical practice guidelines
• Strategy for Patient-Oriented Research (SPOR) Support Units continue to operate in all Canadian provinces, in order to assist decision-makers in providing evidence-based healthcare solutions to patients and communities
• The Drug Safety and Effectiveness Network completed a rapid review publication (abstract) on the effectiveness and safety of antiviral or antibody treatments for coronavirus
• The Canadian Research Initiative in Substance Misuse (CRISM) is rapidly developing a series of six national guidance documents that address the urgent needs of people who use substances, service providers and decision makers in relation to the COVID-19 pandemic
• The Canadian Longitudinal Study on Aging (CLSA) is conducting a national study collecting data on aging adults’ experience during COVID-19, which will explore how they cope, the impacts on their physical and mental health, and changes to how they access health-care services.

CIHR-funded COVID-19 research outputs

Articles

• The spike glycoprotein of the new coronavirus 2019-nCoV contains a furinlike cleavage site absent in CoV of the same clade
• U of A virology lab finds drug originally meant for Ebola is effective against a key enzyme of coronavirus that causes COVID-19
• Estimating the infection and case fatality ratio for coronavirus disease (COVID-19) using age-adjusted data from the outbreak on the Diamond Princess cruise ship, February 2020
• Mathematical modelling of COVID-19 transmission and mitigation strategies in the population of Ontario, Canada [ PDF (508 KB) - external link ]
• Do not violate the International Health Regulations during the COVID-19 outbreak
• Coronavirus COVID-19 impacts to dentistry and potential salivary diagnosis
• Novel Insights Into Immune Systems of Bats
• Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System?
• 2019-nCoV (Wuhan virus), a novel Coronavirus: human-to-human transmission, travel-related cases, and vaccine readiness
• A Comparative Analysis of Factors Influencing Two Outbreaks of Middle Eastern Respiratory Syndrome (MERS) in Saudi Arabia and South Korea
• The human coronavirus HCoV-229E S-protein structure and receptor binding
• Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target
• Similarity in Case Fatality Rates (CFR) of COVID-19/SARS-COV-2 in Italy and China
• As COVID-19 cases, deaths and fatality rates surge in Italy, underlying causes require investigation
• COVID-19 randomised trial protocols: rapid publication without barriers

Pre-prints*

• Safety and effectiveness of dose-sparing strategies for seasonal influenza vaccine: a rapid scoping review of fractional dosing of the intramuscular influenza vaccine
• Estimated surge in hospitalization and intensive care due to the novel coronavirus pandemic in the Greater Toronto Area, Canada: a mathematical modeling study with application at two local area hospitals
• Failing our Most Vulnerable: COVID-19 and Long-Term Care Facilities in Ontario
• Mortality from COVID-19 in 12 countries and 6 states of the United States
• Mathematical modeling of COVID-19 transmission and mitigation strategies in the population of Ontario, Canada
• Estimating the maximum daily number of incident COVID-19 cases manageable by a healthcare system
• Potential roles of social distancing in mitigating the spread of coronavirus disease 2019 (COVID-19) in South Korea
• Standardization and Age-Distribution of COVID-19: Implications for Variability in Case Fatality and Outbreak Identification
• Challenges in control of Covid-19: short doubling time and long delay to effect of interventions

* These articles are preprints and have not undergone formal peer review. They should not be regarded as conclusive, guide clinical practice or health-related behavior, or be reported in news media as established information.

Date modified:

2020-10-19