Programmatic Grants in Environments, Genes and Chronic Disease
It is now widely recognized that complex interactions between environmental and genetic risk factors contribute to the etiology of many non-communicable chronic diseases. The Programmatic Grants in EGCD will address critical knowledge gaps in this area by supporting research to address how interactions between environmental, microbiome, and genetic factors contribute to chronic, non-communicable disease. The importance of this research area is outlined in a podcast by Dr. Philip Sherman, former Scientific Director of CIHR-INMD.
To support interdisciplinary programmatic research that improves our understanding of how environment-gene interactions or environment-microbiome-gene interactions contribute to both metabolic and immunologically-mediated non-communicable chronic diseases;
To support interdisciplinary programmatic research on the etiology of chronic non-communicable disease that may ultimately contribute to the development of new intellectual property, research methodology (including new methods for measuring environmental exposures) and/or approaches for disease prevention or treatment; and
To build interdisciplinary collaborations and foster Canadian expertise in order to elucidate the environmental and genetic origins of non-communicable chronic disease.
CIHR-INMD, in collaboration with funding partners Genome British Columbia and Crohn’s and Colitis Canada, congratulate the successful applicants for this competition.
Vernon Dolinsky, James Davie, Michael Kobor, Garry Shen, Brandy Wicklow
University of Manitoba
The Developmental Origins of Obesity and Obesity-related Complications in Children.
Alberto Martin, Catherine O'Brien
University of Toronto
The impact of the gut microbiome and environment on the development of colorectal cancer.
Gregory Steinberg, Katherine Morrison
Gene Environment Team on Brown/beige Adipose Tissue (GET_BAT).
Alain Stintzi, Daniel Figeys, David Mack, Kieran O'Doherty, and Bruce Vallance
University of Ottawa
The diet-microbiota-gut axis in pediatric IBD.
Stuart Turvey, Jeffrey Brook, Michael Kobor
University of British Columbia
Programmatic research to understand how modifiable environmental factors interact with the genome in the development of asthma.
Jennifer Gommerman, Kenneth Croitoru
University of Toronto
Elucidating the Gene-Environment Interactions that drive Autoimmune Disease among South Asian Canadians - The GEMINI Program.
Philip Awadalla, Trevor Dummer, John Spinelli
Ontario Institute for Cancer Research (Toronto, Ontario)
Determining the genetic and environmental factors associated with metabolic phenotypes across Canada.
Padmaja Subbarao, Jeffrey Brook, Russell De Souza, Qingling Duan, Anita Kozyrskyj, Wen-Yi Lou, Michael Surette
Hospital for Sick Children (Toronto)
Gene and environment effects on lung health and risk for chronic respiratory disease, asthma & COPD.