Consortium Pays-Bas–Canada de recherche sur le diabète de type 2 : projets sur le diabète financés par les IRSC
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L'information est fournie dans la langue dans laquelle le récipiendaire l'a présentée. Pour lire le résumé de chaque projet, cliquez sur le titre du projet en hyperlien.
| Chercheur principal | Établissement | Nom du programme | Titre du projet de recherche | Mots-clés |
|---|---|---|---|---|
| Abizaid, Alfonso | Carleton University (Ottawa) | Subvention de fonctionnement | Stress and Obesity: the Ghrelin connection | Ghrelin; Ghrelin Receptors; Hypothalamus; Obesity; Social Stress; Ventral Tegmentum |
| Abizaid, Alfonso | Carleton University (Ottawa) | Subvention de fonctionnement | Stress and Obesity: the Ghrelin connection | Dorsomedial Nucleus Of The Hypothalamus; Ghrelin; Ghrelin Receptors; Hypothalamus; Nucleus Of The Solitary Tract; Obesity; Parabrachial Nucleus; Social Stress; Ventral Tegmentum |
| Adeli, Khosrow | Hospital for Sick Children (Toronto) University of Toronto |
Subvention de fonctionnement | Mechanisms of intestinal lipoprotein overproduction in insulin resistant states | Animal Models; Apolipoprotein B; Cell Biology; Diabetes; Insulin Resistance; Intestine |
| Adeli, Khosrow | Hospital for Sick Children (Toronto) University of Toronto |
Subvention Fondation | Fundamental and Translational Studies of Diabetic Dyslipidemia in Insulin Resistant States | Biomarkers; Clinical Biochemistry; Laboratory Medicine; Lipoprotein Metabolism; Lipoproteins; Reference Intervals |
| Advani, Andrew | St. Michael's Hospital (Toronto) University of Toronto |
Subvention Projet | Non-coding RNA in diabetic kidney disease | Animal Models; Cell Culture; Diabetes; Diabetic Complications; Diabetic Nephropathy; Epigenetic; Glucose; Kidney; Long Non-Coding Rna; Translational Research |
| Advani, Andrew | St. Michael's Hospital (Toronto) University of Toronto |
Subvention de fonctionnement | Exploring the therapeutic potential of SDF-1 modulation in chronic kidney disease | Chronic Kidney Disease; Diabetic Nephropathy; Focal Segmental Glomerulosclerosis; Hypertension; Sdf-1; Vegf |
| Advani, Andrew | St. Michael's Hospital (Toronto) University of Toronto |
Subvention de fonctionnement | JAK2 and podocytes in diabetic nephropathy | Angiotensin Ii; Diabetes; Diabetic Nephropathy; Glucose; Jak2; Kidney; Podocyte |
| Agarwal, Gina (Ragini) | McMaster University | Subvention de fonctionnement | A Community Paramedicine Initiative for Older Adults Living in Subsidized Housing | Chronic Disease Management; Health Promotion/Disease Prevention; Low Income Older Adults; Paramedics; Qualitative; Quantitative |
| Alarcon, Emilio I | University of Ottawa Heart Institute/Institut de cardiologie de l'Université d'Ottawa University of Ottawa/Université d'Ottawa |
Subvention Projet | Multilayer Hybrid Biomaterial for Treatment of Diabetic Foot Ulcers | Collagen Hydrogel; Diabetic Foot Ulcers; Infection; Nanosilver; Tissue Engineering; Wound Healing |
| Alquier, Thierry | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention de fonctionnement | Role of the hypothalamo-pancreatic axis in the pathogenesis of type 2 diabetes | Beta Cell Function; Beta Cell Mass; Hypothalamus; Insulin Sensitivity; Intracellular Metabolism; Neurons; Neuropeptides; Nutrient Sensing Mechanisms; Type 2 Diabetes |
| Alquier, Thierry | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention Projet | Gliopeptidic regulation of hypothalamic neuronal circuitry by endozepines and energy balance | Astrocytes; Central Nervous System; Endozepines; Energy Balance & Homeostasis; Gliotransmission; Hypothalamus; Melanocortin; Neuroendocrinology; Obesity; Type 2 Diabetes |
| Alquier, Thierry | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention de fonctionnement | Role of the hypothalamo-pancreatic axis in the pathogenesis of type 2 diabetes | Beta Cell Function; Beta Cell Mass; Hypothalamus; Insulin Sensitivity; Nutrient Sensing Mechanisms; Type 2 Diabetes |
| Amed, Shazhan | University of British Columbia | Subvention de fonctionnement : des connaissances à la pratique | Tele-SCOPE - Translation, Evaluation and Learnings Exchanged for Sustainable Childhood Obesity Prevention Through Community Engagement | Action; Childhood; Community; Engagement; Exchange; Knowledge; Obesity; Participatory; Prevention; Sustainable |
| Amed, Shazhan | University of British Columbia | Subvention de fonctionnement : santé maternelle et infantile | Developing a framework for evaluating a comprehensive provincial health care model for children with diabetes using existing population databases | British Columbia; Diabetes; Existing Population Databases; Pediatrics; Performance Evaluation Framework; Quality Of Care |
| Amsden, Brian G | Queen's University (Kingston, Ontario) | Subvention de fonctionnement | Injectable Formulations For Growth Factor Delivery | Biocompatibility; Biodegradable Polymers; Controlled Release; Hepatocyte Growth Factor; Polymer Synthesis; Therapeutic Angiogenesis; Vascular Endothelial Growth Factor |
| Anand, Sonia S | McMaster University | Subv. fonctionnement : Alliance pour la santé de la Première Nation de Fort McKay | Fort McKay First Nations Health Alliance Cohort Enhancement | Aboriginal People; Air Pollution; Cancer; Cardiovascular; Contextual Factors; Diabetes; Environment; Health Risk Factors; Mri; Obesity |
| Anand, Sonia S | McMaster University | Équipes de collaboration indo-canadiennes de recherche en obésité infantile | Understanding the determinants of adiposity among newborns of Indian ancestry in Canada and India. | Birth Cohort; Cardiovascular; Childhood; Culture; Environment; Fetal; Genetic; Maternal; Obesity; South Asian |
| Anand, Sonia S | McMaster University | Subvention Fondation | Deciphering the causes of, and developing interventions to reduce, cardio-metabolic risk factors among ethnic groups in Canada | Cardiovascular Disease; Diabetes; Ethnicity; Metabolic Syndrome; Risk Factors |
| Anand, Sonia S | McMaster University | Sub fonct-AP: Formes savoir autochtone et «double regard» (finance. transitoire) | Aboriginal Birth Cohort (ABC) Project | Aboriginal; Birth Cohort; Breastfeeding; Cardiovascular Disease; Childhood Obesity; Infant Nutrition |
| Anand, Sonia S | McMaster University | Subv de fonct - AP : santé des Premières nations, des Inuits et/ou des Métis | Aboriginal Birth Cohort (ABC) Project | Aboriginal; Birth Cohort; Cardiovascular Disease; Childhood Obesity; Diabetes; Genetics |
| Anand, Sonia S | McMaster University | Sub fonct : sub rech program alimentation & santé-Rech en santé populations | Understanding the impact of maternal and infant nutrition on infant/child health. | Aboriginal; Birth Cohort; Cardio-Metabolic; Dietary Patterns; Epigenetics; Ethnicity; Gene-Diet Interactions; Maternal And Child Health; Microbiome; Nutrition |
| Anderson, Colin C | University of Alberta | Subvention Projet | Co-inhibitory control of tolerance checkpoints | Autoimmune Disease; Diabetes; Flow Cytometry; Immunology; Tolerance; Transplantation |
| Anderson, Deborah H | University of Saskatchewan | Subv. de fonct.-AP-Programme de partenariats régionaux - Saskatchewan | Regulation of PTEN | Breast Cancer; Pi3k/Pten Pathway; Protein Crystallization & Structure Determination; Protein:Protein Interactions; Surface Plasmon Resonance; Tumor Suppressor Protein |
| Anderson, Laura N | McMaster University | Subv de fonctionnement : rech interventionnelle en santé des populations | Evaluation of the Healthy Kids Community Challenge in Early Childhood | Disease Prevention; Early Childhood; Epidemiology; Nutrition; Obesity; Physical Activity; Population Health Intervention; Quasi-Experimental |
| Ansley, David M | University of British Columbia | Subvention de fonctionnement | PRO-TECT II: Propofol cardioprotection for type II diabetics | Antiapoptotic Signaling Pathway; Aortocoronary Bypass Surgery; Apoptosis; Diabetes; Enzyme Assay; Immunohistochemistry |
| Arnason, Terra | University of Saskatchewan | IRSC/ Programme de partenariats régionaux/Subvention de fonctionnement | The role of ubiquitin in the molecular regulation of yeast AMP-activated protein kinase (AMPK), the SNF1 Kinase. | Coimmunoprecipitation; Metabolic Adaptation; Protein Mutagenesis; Protein Stability And Associations; Ubiquitination; Yeast Genetics |
| Atkinson, Stephanie A | McMaster University | Subvention de fonctionnement | Be Healthy in Pregnancy (BHIP) with Nutrition & Exercise | Body Composition; Clinical Trial; Exercise Intervention; Fetal Determinants Of Infant Outcomes; Knowledge Translation; Maternal Mental Health; Nutritional Intervention; Obesity; Pregnancy Outcomes; Primary Care |
| Lambert, Marie | Centre hospitalier universitaire Sainte-Justine Université de Montréal |
Subvention de fonctionnement | Predictors and modifiers of the cardiometabolic risk profile in children | Body Composition; Cardiometabolic Risk Factors; Children; Genetics; Growth; Nutrition; Obesity; Physical Activity |
| Batal, Malek | Université de Montréal | Subv de fonctionnement : rech interventionnelle en santé des populations - Pathways | Evaluation of the Health and Health Equity Outcomes of Okanagan Sockeye Salmon Reintroduction Initiatives | Diet Quality; Ecosystem Recovery; Food Sovereignty; Health Equity; Indigenous Health; Multi-Method Research; Nutrition; Obesity/Diabetes; Qualitative Research; Surveys |
| Beanlands, Rob | University of Ottawa Heart Institute/Institut de cardiologie de l'Université d'Ottawa University of Ottawa/Université d'Ottawa |
Subvention Projet | The Canadian Study of Arterial Inflammation in Patients with Diabetes and Recent Vascular Events: EvaluatioN of Canakinumab Effectiveness (CADENCE) | Atherosclerosis; Biomarkers; Canakinumab; Cardiovascular Disease; Diabetes; Imaging; Inflammation; Pet |
| Beaulieu, Marie-Dominique | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention de fonctionnement | Impact de la dépression sur les comportements d'autogestion du diabète | Autogestion; Diabète; Dépression; Étude Longitudinale |
| Bello, Aminu | University of Alberta | Subvention Projet | Systematic-Evaluation-Referral-Treatment for Cardiovascular and Renal Risk in Rural/Remote and Northern Alberta Communities (SMART-CARE) | Diabetes; Early Detection And Management; Hypertension; Indigenous Communities; Kidney Disease |
| Belsham, Denise D | University of Toronto | Subvention de fonctionnement | Sensing of peripheral nutrient status by the hypothalamus. | Cell Biology; Energy Homeostasis; Hypothalamus; Inflammatory Response; Insulin Resistance; Insulin Signaling; Neuroendocrinology; Neuronal Cell Lines; Neuropeptides; Nutrients |
| Belsham, Denise D | University of Toronto | Subvention de fonctionnement | Sensing of Peripheral Nutrient Status by the Hypothalamus- from Rodents to Humans. | Cell Biology; Energy Homeostasis; Hypothalamus; Inflammatory Response; Insulin Resistance; Insulin Signaling; Neuroendocrinology; Neuronal Cell Lines; Neuropeptides; Nutrients |
| Bendeck, Michelle P | University of Toronto | Subvention de fonctionnement | The Role of Discoidin Domain Receptor 1 (DDR1) in Vascular Calcification of Atherosclerosis and Diabetes | Atherosclerosis; Diabetes; Discoidin Domain Receptor; Extracellular Matrix; Intracellular Signaling; Mechanotransduction; Transgenic Mice; Vascular Calcification |
| Bérard, Anick | Centre hospitalier universitaire Sainte-Justine Université de Montréal |
Subvention de fonctionnement - Analyse secondaire des bases de données | Antidepressant use during pregnancy and the risk of pregnancy induced hypertension, gestational diabetes, and post-partum depression. | Administrative Health Data; Antidepressants And Pregnancy; Maternal Depression; Maternal Hypertension; Maternal Post-Partum; Perinatal Epidemiology; Pharmacoepidemiology; Population-Based Research |
| Berger, Howard | St. Michael's Hospital (Toronto) University of Toronto |
Subv d'équipe: Équipes cliniciens pour rech. en obs. & médecine materno-fœtale | Non-communicable Diseases in Obstetrics: Improving Quality of Care and Maternal-Infant Outcomes through an Obstetrical Research Network | Diabetes In Pregnancy; Health Outcomes; Hypertensive Disorders Of Pregnancy; Knowledge Translation; Obesity; Pregnancy; Prenatal Screening; Quality Of Care |
| Bertolo, Robert F | Memorial University of Newfoundland | Subvention de fonctionnement | Methyl and methionine metabolism in neonates | Amino Acids; Early Programming Of Adult Diseases; Isotope Kinetics; Metabolism; Methionine; Methyl Groups; Neonate; Parenteral Nutrition; Piglet; Requirements |
| Bertolo, Robert F | Memorial University of Newfoundland | Subv de fonct. - AP: Programme de partenariats régionaux-Terre Neuve et Labrador | Impact of dietary methyl groups on methionine metabolism and early programming in neonates | Amino Acids; Early Programming Of Adult Diseases; Isotope Kinetics; Metabolism; Methyl Groups; Piglet; Requirements |
| Beyak, Michael J | Queen's University (Kingston, Ontario) | Subv de fonct - AP : fonds de démarrage de l'INMD (financement provisoire) | Diet induced obesity downregulates gastrointestinal vagal afferent satiety signalling | Electrophysiology; Extracellular Recording; Nodose Ganglion; Obesity; Vagal Afferent; Whole Cell Patch Clamp Recording |
| Beyak, Michael J | Queen's University (Kingston, Ontario) | Subvention de fonctionnement | Diet induced obesity downregulates gastrointestinal vagal afferent satiety signalling | Electrophysiology; Extracellular Recording; Nodose Ganglion; Obesity; Vagal Afferent; Whole Cell Patch Clamp Recording |
| Biddiss, Elaine A | Holland Bloorview Kids Rehabilitation Hospital (Toronto) University of Toronto |
Subvention de fonctionnement | Active video games for promotion of physical activity in children and youth with disabilities: Risks and Benefits | Biomechanics; Cerebral Palsy; Exer-Gaming; Metabolic Expenditure; Physical Activity; Qualitative Research |
| Birken, Catherine S | Hospital for Sick Children (Toronto) University of Toronto |
Subvention de fonctionnement | PROMOTE: Preschoolers at Risk - Obesity trajectories & cardioMetabolic factors: Towards Early identification | Cardiometabolic Risk Factors; Epidemiology; Lifestyle; Longitudinal Cohort; Nutrition; Obesity Prevention; Preschool Children |
| Blackburn, David F | University of Saskatchewan | Subvention de fonctionnement | Major Determinants of Non-Adherence in Saskatchewan (MD-NAS) | Health-Administrative Data; Medication Non-Adherence; Pharmacoepidemiology; Questionnaires |
| Blais, Lucie | Université de Montréal | Subvention de fonctionnement - Analyse secondaire des bases de données | Asthma medications during pregnancy and the risk of hypertensive disorders of pregnancy and gestational diabetes | Administrative Databases; Asthma Medications; Cohort Study; Gestationa Diabetes; Hypertensive Disorders Of Pregnancy; Pregnancy |
| Blanchard, Christopher M | Nova Scotia Health Authority (Halifax) Dalhousie University (Nova Scotia) |
Subv de fonct. - AP : Programme de partenariats régionaux - Nouvelle Ecosse | Lifestyle actIvity correlates For diabEtics (LIFE) | Diabetes; Environment; Gender; Physical Activity; Sex |
| Booth, Gillian L | St. Michael's Hospital (Toronto) University of Toronto |
Subvention Fondation | Building Healthier Cities: a Canadian Initiative To Identify Environmental Solutions to curb obesity (The 'Healthy Cities, Healthier Lives' Research Program) | Built Environment; Diabetes; Food Environment; Obesity; Physical Activity; Population Health; Prevention; Walkability |
| Booth, Gillian L | Institute for Clinical Evaluative Sciences-Toronto University of Toronto |
Subvention de fonctionnement | The urban built environment and health: Implications for diabetes prevention | Administrative Data; Built Environment; Diabetes Mellitus; Epidemiology; Food Environment; Neighbourhood Characteristics; Observational Studies; Public/Population Health; Risk Algorithms; Walkability |
| Borradaile, Nica M | University of Western Ontario | Subv de fonct - AP : fonds de démarrage de l'INMD (financement provisoire) | Roles of elongation factor 1A-1 in apolipoprotein B metabolism and the pathogenesis of nonalcoholic fatty liver disease | Apolipoprotein B; Cellular Stress; Lipid; Liver; Nonalcoholic Fatty Liver Disease; Obesity; Type 2 Diabetes |
| Borradaile, Nica M | University of Western Ontario | Subvention de fonctionnement | Roles of elongation factor 1A-1 in apolipoprotein B metabolism and the pathogenesis of nonalcoholic fatty liver disease | Apolipoprotein B; Cellular Stress; Lipid; Liver; Nonalcoholic Fatty Liver Disease; Obesity; Type 2 Diabetes |
| Bouchard, Luigi | Université de Sherbrooke | Subvention Projet | Developmental origins of childhood obesity: tracking the causal epigenetic changes programming adiposity in children | Barker Hypothesis; Childhood Obesity; Dna Methylation; Epigenetics/Epigenomics; Epigenome-Wide Analysis Study (Ewas); Foetal Development And Growth; Foetal Metabolic Programming; Gestational Hyperglycemia And Diabetes; Mendelian Randomization |
| Hivert, Marie-France | Université de Sherbrooke | Subvention de fonctionnement | Evaluation of contributing heritable and environmental factors to adipokine and glycemic regulation variability during pregnancy and fetal development. | Adipokines; Epidemiology; Epigenetic; Fetal Development; Gestational Diabetes; Glucose Regulation; Heritable Risk Factors; Insulin; Prospective Cohort; Quantitative Traits |
| Bouchard, Luigi | Ecogene-21 (Chicoutimi, Québec) | Subv. de fonct. - AP : santé reproductive et infantile (subvent. de démarrage) | Newborn Epigenetic and Transcriptomic Adaptations to Gestational Diabetes Exposure | Birth Weight; Cord Blood; Dna Methylation; Epigenomics; Fetal Programming; Gestationnal Diabetes; Glucose Intolerance; Obesity; Placenta; Transcriptomics |
| Bouchard, Luigi | Hôpital de Chicoutimi (Québec) | Subv. de fonct.: Subvention de promotion de l'impact : CCREES phase II | Development of a microRNAs-based panel for early prediction of gestational diabetes mellitus | Child And Youth Health; Early Diagnostic; Foetal Metabolic Programming; Gestational Hyperglycemia And Diabetes; Maternal Health In Pregnancy; Micrornas; Mirna-Sequencing; Transcriptomics |
| Bouchard, Maryse | Université de Montréal | Subv. de fonct.: Analyse de bases de données/cohortes existantes - IDSEA | Perinatal Exposure to Perfluoroalkyl Substances (PFASs) and Polybrominated Diphenyl Ethers (PBDEs) and Weight Gain Trajectory in Children: Data from the Maternal-Infant Research on Environmental Chemicals (MIREC) cohort | Children; Environmental Contaminants; Obesity; Perfluoroalkyl Substances (Pfass); Polybrominated Diphenyl Ethers (Pbde); Pregnancy Cohort; Prenatal; Sensitive Window Of Exposure; Weight |
| Boucoiran, Isabelle | Centre hospitalier universitaire Sainte-Justine Université de Montréal |
Subv d'équipe: Équipes cliniciens pour rech. en obs. & médecine materno-fœtale | Montreal Emerging Research Team in Maternal Fetal Medicine (MERe) | Clinical Ethics; Gestational Diabetes; Infectious Disease And Pregnancy; Maternal Conditions And Pregnancy; Materno-Fetal Medicine; Prenatal Diagnosis |
| Boulianne, Gabrielle L | Hospital for Sick Children (Toronto) University of Toronto |
Subvention de fonctionnement | Drosophila Models of Human Obesity | Appetite; Cns; Diet; Drosophila; Feeding Behavior; Gene-Environment Interaction; Gene-Gene Interaction; Genetics; Obesity |
| Boyle, Michael H | McMaster University | Subvention de fonctionnement | Psychiatric comorbidity in children with chronic physical illness: a pilot study | Child Mental Health; Chronic Illness; Longitudinal Study; Physical Health; Pilot/Feasibility Study; Social Determinant Of Health |
| Braun, Andrew P | University of Calgary | Subvention de fonctionnement | Endothelial ion channels, nitric oxide and the cellular mechanisms regulating vasorelaxation | Electrophysiology; Endothelium; Hypertension And Diabetes; Nitric Oxide; Vascular Myography And Fluorescence Imaging |
| Braun, Andrew P | University of Calgary | Subvention de fonctionnement | Targeting endothelial KCa channels in vascular dysfunction. | Calcium Imaging; Calcium-Activated K+ Channels; Electrophysiology; Endothelium; Pressure Myography; Type 2 Diabetes; Vascular Function |
| Brayer, Gary D | University of British Columbia | Subvention de fonctionnement | Facilitating the Development of New Therapeutics for Diabetes, Pre-Diabetes and Obesity by Inhibition of Human Pancreatic Alpha-Amylase: A Structural and Mechanistic Approach | Diabetes; Enzyme Kinetics; Inhibitor Design And Optimization; Inhibitor Identification And Characterization; Mechanism Based Inhibitor Synthesis; Mechanistic Studies Of Enzymatic Catalysis; Obesity; Protein Structure - Function Relationships; Proteomic Approaches; X-Ray Crystallography |
| Brochu, Michèle | Université de Montréal | Subvention de fonctionnement | Sexe biologique et environnement intrautérin défavorable: adaptation foetale et conséquences à l'âge adulte | Effet Du Sexe; Modèle Animal; Rein; Restriction De Croissance Intrautérin; Système Cardiovasculaire |
| Brown, Craig E | University of Victoria (British Columbia) | Subvention de fonctionnement | Imaging the impact of diabetes on brain function and recovery from stroke | Cortical Plasticity; Diabetes; In Vivo Imaging; Recovery; Sensory Systems; Stroke |
| Brown, Craig E | University of Victoria (British Columbia) | Subvention de fonctionnement | Impact of diabetes on brain function and recovery from ischemic stroke | 2-Photon Microscopy; Angiogenesis; Behaviour; Blood Flow; Diabetes; Imaging; Neural Plasticity; Recovery Of Function; Somatosensory Cortex; Stroke |
| Brown, Hilary | University of Toronto Scarborough (ON) | Subvention Projet | Chronic Medical Conditions and Perinatal Mental Illness | Chronic Medical Conditions; Postpartum Mental Illness; Prenatal Mental Illness |
| Brubaker, Patricia L | University of Toronto | Subvention Projet | Mechanisms underlying circadian secretion of the anti-diabetic hormone, glucagon-like peptide-1: therapeutic potential | Cell Signaling; Circadian; Glp-1; Glucose; In Vitro; In Vivo; Insulin; Intestine; Metabolism; Secretion |
| Bruce, Sharon G | University of Manitoba | Subvention de fonctionnement - AP: Programme de partenariats régionaux: Manitoba | Exploring the role of established and non-traditional risk factors on diabetes and cardiovascular disease among a Manitoba First Nation population. | Aboriginal Health; Cardiovascular Disease; Chronic Disease Etiology; Chronic Diseases; Community Based Participatory Research; Diabetes; Diabetes Complications; Epidemiology; Population Health; Stress |
| Bruce, Sharon G | University of Manitoba | Subv. de fonctionnement - Recherche interv en santé des Autochtones-dem dét. | Developing a Diabetes Prevention Intervention: Identifying and Targeting Contextually-Relevant Stressors | Community-Based Participatory Research; Diabetes Etiology; Diabetes Prevention; Diabetes Risk Factors; Epidemiology; First Nations People; Intervention Planning; Stress |
| Bruin, Jennifer E | Carleton University (Ottawa) | Subvention Projet | Contribution of Dioxin-Like Chemicals to Beta Cell Death and Dysfunction in Diabetes | Diabetes; Environmental Pollutants; Insulin; Islets; Toxicology |
| Brumell, John H | Hospital for Sick Children (Toronto) University of Toronto |
Subvention de fonctionnement | A novel pathway of PI(3,4)P2/PI(3,4,5)P3 production initiated by a bacterial phosphatase | Confocal Microscopy; Lipid Biochemistry; Membrane Trafficking; Phosphoinositide Signaling; Pi3-Kinase; Salmonella Infection |
| Brumell, John H | Hospital for Sick Children (Toronto) University of Toronto |
Subvention de fonctionnement | A novel phosphoinositide signaling pathway contributes to Salmonella pathogenesis | Actin Polymerization; Confocal Microsocpy; Lipid Biochemistry; Membrane Trafficking; Phosphoinositide Signaling; Pi3-Kinase; Rho Gtpase; Salmonella Infection |
| Buckeridge, David L | McGill University/Université McGill | Operating Grant: Advancing Theoretical Method. Innovations Hlth Res - POP | Non-communicable disease indicators for use in a Population Health Record (PopHR): development and validation | Diet; Health Outcomes; Indicators; Non-Communicable Disease; Public Health Informatics; Surveillance |
| Bull, Shelley B | Sinai Health System (Toronto)University of Toronto | Subvention de fonctionnement | Analytic Methods for the Next Generation of Complex Trait Studies | Complex Traits; Gene By Environment; Genetic Epidemiology; Genome-Wide Studies; Longitudinal Study Design; Statistical Genetics |
| Burger, Dylan E | Ottawa Hospital Research Institute/Institut de recherche de l'Hôpital d'Ottawa University of Ottawa/Université d'Ottawa |
Subvention Projet | Microparticles in Diabetes | Diabetes; Endothelial; Hyperglycemia; Microparticles; Peptidylarginine Deiminase; Thrombospondin; Vascular Dysfunction |
| Burger, Dylan E | Ottawa Hospital Research Institute/Institut de recherche de l'Hôpital d'Ottawa University of Ottawa/Université d'Ottawa |
Subvention Projet | Mechanisms of endothelial microparticle formation and signaling in diabetes | Biomarker; Cell Biology; Diabetes; Endothelial; Extracellular Vesicles; Inflammation; Microparticles; Reactive Oxygen Species; Vascular; Vessel Myography |
| Buschmann, Michael D | École polytechnique de MontréalUniversité de Montréal | Subvention de fonct : prog de rech en collab avec l'industrie - Autre partenaire | Gene Delivery of Glucagon-like Peptide-1 (GLP-1) for the Treatment of Type 2 Diabetes | Chitosan; Diabetes; Gene Delivery; Glucagon-Like Peptide-1; Nanomedicine |
| Buteau, Jean | University of Alberta | Subvention de fonctionnement | Role of SirT1 in the regulation of pancreatic beta-cell mass and function | Animal Models; Apoptosis; Diabetes; Gene Expression; Insulin Secretion; Metabolism; Pancreatic Beta-Cells; Proliferation; Transcription Factors |
| Buteau, Jean | University of Alberta | Subvention de fonctionnement | Glucagon-like peptide-1 and pancreatic beta-cell neogenesis | Diabetes; Differentiation; Growth Factor; Pancreatic Beta-Cell; Proliferation; Signal Transduction |
| Buteau, Jean | University of Alberta | Subvention Projet | Role of the non-receptor tyrosine kinase Lyn in the regulation of pancreatic beta-cell mass and function | Apoptosis; Beta-Cell; Cell Signalling; Diabetes; Kinase; Proliferation; Signal Transduction |
| Campbell, Robert J | Queen's University (Kingston, Ontario) | Subvention Projet | Comparative safety of aflibercept and ranibizumab in the treatment of retinal diseases | Aflibercept; Comparative Safety; Drug Safety; Health Services Research; Ophthalmology; Ranibizumab; Retinal Diseases |
| Carpentier, André C | Université de Sherbrooke | Subvention de fonctionnement | Investigation of postprandial fatty acid metabolism in the natural history of type 2 diabetes mellitus (T2D) | Diabetes Mellitus; Insulin Resistance; Lipid Metabolism; Positron Emission Tomography; Postprandial Lipoprotein Metabolism; Stable Isotopes |
| Carpentier, André C | Université de Sherbrooke | Subvention Projet | Quantifying Brown Adipose Tissue Thermogenesis in Obesity and Type 2 Diabetes | Brown Adipose Tissue; Energy Metabolism; Fatty Acid Metabolism; Magnetic Resonance Imaging; Molecular Imaging; Obesity; Positron Emission Tomography; Tracer Methods; Triglycerides; Type 2 Diabetes |
| Carpentier, André C | Université de Sherbrooke | Subvention de fonctionnement | Investigation of postprandial fatty acid metabolism in the natural history of type 2 diabetes mellitus (T2D) | Diabetes Mellitus; Insulin Resistance; Lipid Metabolism; Positron Emission Tomography; Postprandial Lipoprotein Metabolism; Stable Isotopes |
| Carpentier, André C | Université de Sherbrooke | Subvention de fonctionnement | Mechanisms of improved glucose metabolism after bariatric surgery in type 2 diabetes | Bariatric Surgery; Diabetes Mellitus; Fatty Acid Metabolism; Insulin Resistance/Secretion; Obesity; Postprandial Metabolism |
| Carpentier, André C | Université de Sherbrooke | Subvention de fonctionnement | Postprandial energy metabolism of brown fat in humans | Brown Adipose Tissue; Diabetes Mellitus; Insulin Resistance; Lipid Metabolism; Positron Emission Tomography; Postprandial Lipoprotein Metabolism; Postprandial Thermogenesis; Stable Isotopes |
| Cattini, Peter A | University of Manitoba | Subvention de fonctionnement | Activation, Expression and Hormonal Regulation of the Human Pituitary Growth Hormone Gene | Chromatin Remodeling/Gene Activation; Disorders Related To Dysregulation Of Growth Hormone; Hormonal (Glucocorticoid And Insulin) Regulation; Human Pituitary Growth Hormone Gene; Tissue-Specific Regulation; Transcriptional Regulation/Gene Expression |
| Cattini, Peter A | University of Manitoba | Subvention de fonctionnement - AP: Programme de partenariats régionaux: Manitoba | Obesity and Development of a Diabetes Mellitus-Like State in Pregnancy: Investigating a Role for Regulation of the Human Placental Growth Hormone Genes | Epigenetic Events/Non-Coding Rnas; High Fat Diet-Induced Gestational Diabetes; Human Placenta; Human Placental Hormone Genes; Pregnancy; Transgenic Mice |
| Cechetto, David F | University of Western Ontario | Subv d'équipe émergente : comorb des troubles cérébraux et autres prob-dem dét | CIHR Team in Vascular Cognitive Impairment: Animal Models of Co-morbidity | Alzheimer's Disease; Diabetes; Neurodegeneration; Neuroinflammation; Stroke; Vascular Cognitive Impairment |
| Chakrabarti, Subrata | University of Western Ontario | Subvention Projet | Novel mechanisms in diabetic cardiomyopathy | Cardiac Functional Changes; Cardiac Structural Changes; Cardiomyocytes; Diabetic Cardiomyopathy; Endothelial Cells; Methylation; Non-Coding Rna |
| Chan, John S | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention de fonctionnement | Reactive Oxygen Species, Bcl-2-Modifying Factor and Tubular Atrophy in Diabetic Kidneys | Bcl-2-Modifying Factor; Diabetic Nephropathy; Glucose Signaling; Insulin Signaling; Kidney; Molecular Biology; Oxidative Stress; Physiology; Renin-Angiotensin System; Transgenic And Knockout Mice |
| Chan, John S | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention de fonctionnement | Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) in the Progression of Diabetic Nephropathy: Friend or foe? | Angiotensinogen; Diabetes; Diabetic Nephropathy; Heterogeneous Nuclear Ribonucleoproteins; Hypertension; Knockout Mice; Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2); Oxidative Stress; Renin-Angiotensin System; Transgenic Mice |
| Chan, John S | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention de fonctionnement | Diabetes and the mechanism(s) of renal tubular apoptosis in db/db mouse kidneys | Albumin; Angiotensinogen; Caspase-12 Gene Expression; Diabetic Nephropathy; Molecular And Cell Biology; Oxidative Stress; Renal Proximal Tubular Cells; Renin-Angiotensin System; Transgenic Mice; Tubular Apoptosis And Atrophy |
| Chan, John S | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention de fonctionnement | Hypertension and regulation of angiotensinogen gene expression in transgenic mice | Angiotensinogen Gene; Diabetes; Heterogenous Ribonucleoprotein F; Hypertension; Kidney; Transgenic Mice |
| Cheeseman, Christopher I | University of Alberta | Subvention de fonctionnement | Characterization of a novel urate transporter in the kidney and colon. | Electrophysiology; Heterologous Expression; Metabolic Disease; Pcr; Site Directed Mutagenesis; Urate Transport |
| Chemtob, Sylvain | Centre hospitalier universitaire Sainte-Justine Université de Montréal |
Subvention Fondation | Choroidopathies in retinopathies: pathogenesis and therapeutic discoveries | Aging; Angiogenesis; Choroid; Inflammation; Ischemia; Newborn; Oxidant Stress; Photoreceptors; Retina; Vasoobliteration |
| Chemtob, Sylvain | Centre hospitalier universitaire Sainte-Justine Université de Montréal |
Programme de démonstration des principes - phase II | IL-1 Allosteramers to treat diabetes and its complications | Allosteramer; Diabetes; Il-1beta; Inflammation; Interleukin |
| Chevalier, Stéphanie | Research Institute of the McGill University Health Centre/Institut de recherche du Centre universitaire de santé McGill McGill University/Université McGill |
Subvention de fonctionnement | Protein metabolism and insulin resistance in cancer cachexia: a potential anabolic role of leucine | Gluconeogenesis; Insulin Resistance; Leucine; Lung Cancer; Protein Metabolism; Stable Isotope Kinetic Studies |
| Chin Sang, Ian D | Queen's University (Kingston, Ontario) | Subvention de fonctionnement | The Role of Eph and Insulin Receptor Tyrosine Kinase Signaling in C. elegans Neurodevelopment | Axon Guidance; C. Elegans; Cancer; Cell Migration; Eph Receptor Tyrosine Kinase; Genetics; Insulin Signaling; Morphogenesis; Pten; Signal Transduction |
| Chin Sang, Ian D | Queen's University (Kingston, Ontario) | Subvention Projet | The role of Insulin signaling in neuronal development. | C. Elegans; Cell Biology; Genetics; Insulin Growth Factors; Insulin Signaling; Neurodevelopment; Neuropeptides |
| Christian, Sherri L | Memorial University of Newfoundland | Subv de fonct. - AP: Programme de partenariats régionaux-Terre Neuve et Labrador | Mechanisms of molecular regulation of pre-adipocyte differentiation by CD24 | Adipogenesis; Bioinformatics; Cd24; Gene Expression Profiling; Gene Expression Regulation; Lipodystrophies; Obesity; Pre-Adipocyte; Signal Transduction |
| Cianflone, Katherine M | Institut universitaire de cardiologie et de pneumologie de Québec - ULaval Université Laval |
Subvention de fonctionnement | ASP Deficient and ASP Excess Mice Models: Immune-Metabolic Interactions in Adipose Tissue and Energy Expenditure Regulation | Adipose Tissue; Cell Biology; Diabetes; Mice Models; Obesity; Peptide Hormones |
| Cianflone, Katherine M | Université Laval | Subvention de fonctionnement HOPE du Canada | Hormonal and Mechanistic Evaluation of Increasing risk of diabetes and Cardiovascular Disease in India: from Bench to Bedside. | Adipokines; Adipose Tissue; Cardiovascular Disease; Insulin Resistance; Subcutaneous; Visceral |
| Clandinin, Michael T | University of Alberta | Subvention de fonctionnement | Physiological factors that determine quantity of in vivo synthesis of palmitate, palmitoleate, stearate and oleate in humans | Chronic Disease Risk; De Novo Lipogenesis; Fat Metabolism; Human Research; Stable Isotopes; Substrate Utilization |
| Coderre, Terence J | McGill University/Université McGill | Programme de démonstration des principes - phase I | Synergistic topical combinations for chronic pain aimed at treating microvascular dysfunction. | Allodynia; Commercialization; Laser Doppler; Microvascular Dysfunction; Nociception; Pain; Side-Effects; Synergy; Tissue Oxygenation; Topical Application |
| Cole, William C | University of Calgary | Subvention de fonctionnement | Integrin Adhesion Signaling in the Cerebral Arterial Myogenic Response | Cerebral Blood Flow Autoregulation; Cytoskeleton Reorganization; Goto-Kakizaki Type 2 Diabetic Rat; Myogenic Response; Myosin Light Chain Phosphatase; Rho Kinase Phosphorylation; Spontaneously Hypertensive Rat; Stroke-Prone Hypertensive Rat; Vascular Smooth Muscle; Vasoconstrictor |
| Cole, William C | University of Calgary | Subvention de fonctionnement | The Cerebral Arterial Myogenic Response in Health and Disease | Cerebral Blood Flow Autoregulation; Cytoskeleton Reorganization; Goto-Kakizaki Type 2 Diabetic Rat; Myogenic Response; Myosin Light Chain Phosphatase; Rho Kinase Phosphorylation; Spontaneously Hypertensive Rat; Stroke-Prone Hypertensive Rat; Vascular Smooth Muscle; Vasoconstrictor |
| Connelly, Philip W | St. Michael's Hospital (Toronto) University of Toronto |
Subvention de fonctionnement | Investigating the role of red blood cells in oxidative stress and thrombogenesis - from 4-hydroxynonenal chemistry to mouse to man. | Alpha; Beta Unsaturated Aldehydes; Diabetes; Gamma-Glutamyltranspeptidase; Glutathione; Paraoxonase 1; Platelets; Red Blood Cells |
| Corbett, Dale R | Memorial University of Newfoundland | Subvention de fonctionnement | Recovery of function following stroke | Aging; Behaviour; Co-Morbidity; Neuroplasticity; Recovery Of Function; Stroke |
| Cordes, Sabine P | Lunenfeld-Tanenbaum Research Institute (Toronto) University of Toronto |
Subvention de fonctionnement | Analysis of the role of the Gumby gene in angiogenesis | Angiogenesis; Craniofacial Syndromes; Development; Molecular Genetics; Mouse Genetics |
| Couture, Patrick | Université Laval | Subvention de fonctionnement | Effects of medium-chain triglycerides on chylomicron secretion and expression of genes that regulate intestinal lipid metabolism in men with dyslipidemia associated with the metabolic syndrome | Gene Expression; Intestinal Lipoprotein Metabolism; Metabolic Syndrome |
| Couture, Patrick | Université Laval | Subvention de fonctionnement | Differential effects of saturated and polyunsaturated fatty acids on chylomicron secretion and expression of key genes and proteins that regulate intestinal lipid metabolism in men with dyslipidemia associated with insulin-resistance | Gene Expression; Insulin-Resistance; Intestinal Lipoprotein Metabolism; Nutrition; Proteomic |
| Couture, Patrick | Université Laval | Subvention Projet | Differential effects of saturated and monounsaturated fatty acids on chylomicron secretion and the expression of key genes that regulate intestinal lipid metabolism in insulin-resistant subjects | Gene Expression; Insulin-Resistance; Intestinal Lipoprotein Metabolism; Nutrition |
| Couture, Réjean | Université de Montréal | Subvention de fonctionnement | Kinin B1 receptor as a key target in the treatment of hypertension and insulin resistance | Arterial Hypertension; Cardiovascular; Central Nervous System; Insulin Resistance; Oxidative Stress; Pharmacology; Vascular Inflammation; Vasoactive Peptides |
| Cross, Karen M | St. Michael's Hospital (Toronto) University of Toronto |
Subvention Projet | Development of the MultIspectral MObile tiSsue Assessment (MIMOSA) device | Magnetic Resonance; Methemoglobin; Multispectral; Optical Imaging; Oxygenation; Tissue Perfusion |
| Crowshoe, Lynden L | Alberta Health ServicesUniversity of Alberta | Subvention Projet | Educating For Equity: Indigenous Patient Empowerment through Critical Education of Patients and Physicians in Addressing Social Pathways to Diabetes | Care Framework; Health Literacy; Indigenous; Patient Empowerment; Primary Care; Psycho-Education; Type 2 Diabetes |
| Cullis, Pieter R | University of British Columbia | Subvention Fondation | Lipid nanomedicines for health and disease | Anticancer; Drug Delivery System; Gene Therapy; Immunosuppressant; Lipid Nanoparticles; Mrna; Nanomedicine; Sirna; Small Molecule Drugs; Trigger Release |
| Cummins, Carolyn L | University of Toronto | Sub de fonctionnement : programme de recherche en collaboration avec l'industrie | Defining the structural basis for LXR beta antagonism | Co-Transfection Assays; Dexamethasone; Ligand Binding Assays; Liver X Receptor; Nuclear Receptor; P450 Metabolism; Physicochemical Properties; Primary Hepatocytes; Structure Based Drug Design; Synthetic Chemistry |
| Cummins, Carolyn L | University of Toronto | Subvention Projet | Nuclear Receptor Signaling in High-Fat Diet and Glucocorticoid-Induced Metabolic Disease | Adipose; Arglu1; Chromatin Immunoprecipitation; Coregulator; Energy Expenditure; Glucocorticoid; Liver; Metabolic Disease; Nuclear Receptor; Rna-Seq |
| Cummins, Carolyn L | University of Toronto | Subvention de fonctionnement | Role of LXRbeta in Glucocorticoid-Induced Hyperglycemia | Diabetes; Glucocorticoids; Glucose Metabolism; Knockout Mice; Lxr; Signalling |
| Cummins, Carolyn L | University of Toronto | Programme de démonstration des principes - phase I | Developing a Novel Therapeutic for Cushing's Syndrome | Cushing's Syndrome; Diabetes; Drug Target; Glucocorticoid; Glucocorticoid Receptor; Liver X Receptor; Muscle Wasting; Obesity; Osteoporosis |
| Cummins, Carolyn L | University of Toronto | Subvention de fonctionnement | Molecular Determinants of Corticosteroid Actions in Glucose Metabolism | Animal Model; Chromatin Immunoprecipitation; Coactivator; Fgf21; Glucocorticoid Receptor; Gluconeogenesis; Hepatosteatosis; Liver X Receptor Beta; Lxr Antagonist; Stress Hormone |
| Dacosta, Ralph S | University Health Network (Toronto) University of Toronto |
Subvention Projet | The FL.I.G.H.T (Fluorescence Image-Guided Healing Trial) for Diabetic Foot Ulcers: A Single Centre Phase II Trial | Bacteria; Diabetes Wound Complications; Diabetic Foot Ulcers; Fluorescence Imaging; Health Economics; Microbiology; Quality Of Life; Wound Debridement; Wound Healing; Wound Sampling |
| Dagher, Alain | Montreal Neurological Institute/Institut neurologique de Montréal McGill University/Université McGill |
Subvention de fonctionnement | Ghrelin and the CNS control of appetite. | Fmri; Ghrelin; Obesity; Reward; Stress |
| Dallaire, Clémence | Université Laval | Partenariats pour l'amélioration du système de santé (PASS) | L'implantation d'une clinique de suivis intégrés de maladies chroniques en misant sur la deuxieme ligne de soins | Diabète; Implantation d'un suivi; Maladies inflammatoires; Pratiques de gestion; Pratiques professionnelles; Suivi des maladies chroniques |
| Danska, Jayne S | Hospital for Sick Children (Toronto) University of Toronto |
Subvention Projet | Mechanisms of Inflammation, Immunity and Islet Dysfunction in Diabetes (MI3D) | Flow Cytometry; Gene/Environment Interaction; Genomic Analysis; Gut Microbiome; Human Cohort Studies; Human Diabetes; Immune Responses; Innate Immune Surveillance; Mouse Models; Type 1 Diabetes |
| Dart, Allison B | University of Manitoba | Subvention de fonctionnement | An assessment of psychological factors, inflammatory biomarkers and kidney complications; the Improving renal Complications in Adolescents with type 2 diabetes through REsearch (iCARE) cohort study | Albuminuria; Biomarkers; Cohort; Inflammation; Psychological Factors; Type 2 Diabetes Mellitus; Youth |
| Dasgupta, Kaberi | Research Institute of the McGill University Health Centre/Institut de recherche du Centre universitaire de santé McGill McGill University/Université McGill |
Subvention de fonctionnement | Step Monitoring to improve ARTERial health (SMARTER) | Arterial Stiffness; Behaviour; Cardiovascular Disease Risk Factors; Diabetes; Hypertension; Obesity; Pedometers; Physical Activity; Randomized Controlled Trial |
| Dasgupta, Kaberi | Research Institute of the McGill University Health Centre/Institut de recherche du Centre universitaire de santé McGill McGill University/Université McGill |
Subvention Projet | Amplifying the Step Monitoring to improve ARTERial health strategy (SMARTER amplify) | Applications; Cardiometabolic Risk Factors; Coaching; Pedometers; Peers; Physical Activity |
| Dasgupta, Kaberi | Research Institute of the McGill University Health Centre/Institut de recherche du Centre universitaire de santé McGill McGill University/Université McGill |
Subvention de fonctionnement: Le sucre et la santé - Sucre et santé | Sugar in solid foods and beverages: examining relationships to gestational diabetes and cardiovascular disease | Free Sugars; Gestational Diabetes; Myocardial Infarction; Stroke |
| DaSilva, Jean N | University of Ottawa Heart Institute/Institut de cardiologie de l'Université d'Ottawa University of Ottawa/Université d'Ottawa |
Subvention de fonctionnement | Altered Angiotensin II AT1 Receptor in Cardiac and Renal Disease: Translational Development of Novel F-18 Labeled Ligands for PET Imaging | Candesartan; Diabetes; Echocardiography; Fluoro-18 Analogs; Heart Failure; Hypertension; Losartan; Pet Imaging |
| DaSilva, Jean N | University of Ottawa Heart Institute/Institut de cardiologie de l'Université d'Ottawa University of Ottawa/Université d'Ottawa |
Subv. de fonct -AP : Inst. de la Nutrition, métabolisme, diabète -fin transit. | Effect of Glycemic Therapy on Impaired Myocardial Noradrenergic Innervation and Beta-Adrenoceptors in Rat Models of Diabetes | Cardiovascular Diseases; Hyperglycemia; Insulin Resistance; Noradrenaline; Positron Emission Tomography; Type 2 Diabetes |
| Dawes, Martin G | University of British Columbia | Subv. de fonctionnement de Pfizer en prévention et prise en charge des maladies | Preventing Diabetes with Facilitated Lifestyle Intervention Prescriptions. Phase 2: Pilot Study | Access To Preventive Care; Behaviour Modification; Clinical Trial; Collaborative Practice; Health Promotion; Patient Self-Management Education; Pilot Study; Pre-Diabetes; Primary And Community-Based Healthcare |
| De Koninck, Yves | Centre hospitalier Robert-Giffard (Québec) | Subvention de fonctionnement | Plasticity of inhibition in spinal sensory pathways | Behavioural Pharmacology; Cellular Imaging; Chronic Pain; Electrophysiology; Gaba / Glycine; Immunocytochemistry |
| Delormier, Treena | McGill University/Université McGill | Subv. de fonct.: Environ. réseau pour la recherche sur la santé des Autochtones | Title: Ratikonshatatie, "the faces yet to come": KSDPP Center for Research and Training for Community Mobilization and Knowledge Translation | Capacity Building; Community Mobilisation; Health Promotion; Indigenous Health Research; Knowledge Translation |
| Des Rosiers, Christine | Montreal Heart Institute/Institut de cardiologie de Montréal Université de Montréal |
Subvention de fonctionnement | Investigations of cardiac metabolism using mass isotopomer analysis: A paradigm for biomarker and therapy discovery. | Cardiac Energy Metabolism; Cardiomyopathy; Cgmp Signaling; Diabetes; Heart Perfusion; Mass Spectrometry; Mitochondria; Positron Emission Tomography |
| Després, Jean-Pierre | Institut universitaire de cardiologie et de pneumologie de Québec - ULaval Université Laval |
Subvention de fonctionnement | Visceral obesity/ectopic fat and non-invasive markers of atherosclerosis: A cardiometabolic-cardiovascular imaging study | Atherosclerosis; Cardiometabolic Risk Factors/Markers; Cardiorespiratory Fitness; Cardiovascular Disease And Type 2 Diabetes; Visceral Adiposity/Ectopic Fat |
| Devlin, Angela M | University of British Columbia | Subvention Projet | Maternal Folic Acid and Vitamin B12 intake During Pregnancy and Type 2 Diabetes Risk in Offspring | Developmental Programming; Diabetes; Folic Acid; Islets; Offspring; Pregnancy; Vitamin B12 |
| Dionne, Isabelle | Centre de recherche sur le vieillissement (QC) Université de Sherbrooke |
Subvention de fonctionnement - Annonce de priorités : obésité | Metabolic Characteristics of Overweight Postmenopausal Women First-Degree Relatives of Type 2 Diabetes patients (FDR): How are they different from non-FDR and how do they respond to exercise training? | Body Composition; Ct Scan; Exercise; Fat Metabolism; Glucose Tolerance; Muscle Tissue; Type 2 Diabetes |
| Dodds, Linda | IWK Health Centre (Halifax) Dalhousie University (Nova Scotia) |
Subvention de fonctionnement | Vitamin D status in Canadian pregnant women and their newborn infants: what levels protect against adverse pregnancy outcomes? | 25-Hydroxy Vitamin D; Birth Weight; Cohort; Gestational Diabetes; Nested Case-Control; Pre-Eclampsia; Pregnancy; Small For Gestational Age; Vitamin D |
| Dolinsky, Vernon W | University of Manitoba | Subvention de fonctionnement | Adiponectin in gestational diabetes and the developmental origins of disease. | Adiponectin; Developmental Origins Of Disease; Gene Expression; Gene Therapy; Gestational Diabetes; Hepatic Steatosis; Insulin Resistance; Islet Biology; Mitochondria; Obesity |
| Dosch, Hans-Michael | Hospital for Sick Children (Toronto) University of Toronto |
Subvention de fonctionnement | The Immunology and Neuroscience of Diabetes Mellitus. | B6 Mouse & Congenics; Diet Induced Obesity (Dio); Nod Mouse; Primary Sensory Afferent Neurons; T1d & T2d Patients; Trpv1; Trpv1 Allelic Variants; Type 1 Diabetes (T1d); Type 2 Diabetes (T2d); Visceral Fat-Resident Lymphocytes |
| Doucette, Christine A | University of Manitoba | Subvention Projet | Examining the mechanistic impact of the HNF-1aG319S polymorphism on beta cell function and its contribution to early-onset type 2 diabetes | Beta Cells; Gene Expression; Glucose-Sensing; Islet Biology; Metabolism; Type 2 Diabetes |
| Douros, Antonios | Lady Davis Institute for Medical Research (Mtl) McGill University/Université McGill |
Subvention Projet | Concomitant use of sulfonylureas with warfarin and the risk of severe hypoglycemia in patients with type 2 diabetes | Anti-Diabetic Treatment; Drug-Drug Interaction; Hypoglycemia; Oral Anticoagulants; Type 2 Diabetes |
| Drouin, Jacques | Institut de recherches cliniques de Montréal Université de Montréal |
Subvention de fonctionnement | Transcriptional and epigenetic mechanisms for differentiation of pituitary POMC cells | Cell Differentiation; Chromatin; Pax; Pioneer Factor; Pituitary; Pomc; Repression; Tbox; Transcriptional Coactivators |
| Drucker, Daniel J | Lunenfeld-Tanenbaum Research Institute (Toronto) University of Toronto |
Subvention de fonctionnement | Molecular and cellular mechanisms of dipeptidyl peptidase-4 action | Cardiovascular System; Diabetes; Gut Endocrine System; Peptide Hormones |
| Drucker, Daniel J | Lunenfeld-Tanenbaum Research Institute (Toronto) University of Toronto |
Subvention Fondation | Mechanisms of peptide hormone action: metabolic and therapeutic implications | Gut And Islet Hormones; Metabolism |
| Drucker, Daniel J | Lunenfeld-Tanenbaum Research Institute (Toronto) University of Toronto |
Subvention de fonctionnement | Gipr and the control of glucose homeostasis | Diabetes; Intestine; Obesity; Peptide Hormones |
| Drucker, Daniel J | Lunenfeld-Tanenbaum Research Institute (Toronto) University of Toronto |
Subvention de fonctionnement | Glucagon receptor and the control of metabolism | Diabetes; Gut Endocrine System; Metabolism; Peptide Hormones |
| Drucker, Daniel J | Lunenfeld-Tanenbaum Research Institute (Toronto) University of Toronto |
Subvention de fonctionnement | Elucidation of novel mechanisms of glucagon action | Intestine; Pancreas; Peptide Hormones; Receptors |
| Dubrac, Alexandre | Centre hospitalier universitaire Sainte-Justine Université de Montréal |
Subvention Projet | ALK5-PAR6A signaling pathway regulates endothelial cells proliferation and vascular leakage | Angiogenesis; Cell Polarity; Cell Proliferation; Endothelial Cell; Neonatal Vascular Malformation; Retinopathy; Tgfb |
| Dyck, Jason R | University of Alberta | Subvention de fonctionnement | The Role of Adipose Triglyceride Lipase in the Pathogenesis of Lipotoxic Cardiomyopathy | Adipose Triglyceride Lipase; Ampk; Cardiac Metabolism; Lipid Accumulation; Lipotoxic Cardiomyopathy |
| Ehses, Jan A | University of British Columbia | Subv de fonct- AP : Fonds de démarrage INMD (finance trans)-nouveaux chercheurs | Targeting anti-inflammatory macrophages to treat type 2 diabetes | Diabetes; Inflammation; Insulin; Islets Of Langerhans; Macrophages; Pancreatic Beta Cell |
| Ehses, Jan A | University of British Columbia | Subv de fonct - AP : fonds de démarrage de l'INMD (financement provisoire) | The role of islet macrophages in obesity and type 2 diabetes: from pro-inflammation to regeneration. | Diabetes; Inflammation; Insulin; Islets Of Langerhans; Macrophages; Pancreatic Beta Cell; Regeneration |
| Engler-Stringer, Rachel R | University of Saskatchewan | Subv de fonctionnement : rech interventionnelle en santé des populations | The Good Food Junction: A Community-Based Food Intervention to Reduce Nutritional Health Inequities | Community-Based Research; Mixed Methods; Nutrition Inequalities Research; Population Health Intervention |
| Estall, Jennifer | Institut de recherches cliniques de Montréal Université de Montréal |
Subvention Projet | PGC-1a co-activators in beta-cell function and survival | Apoptosis; Beta-Cells; Diabetes; Insulin Secretion; Islet; Metabolism; Mouse Models; Pgc-1; Snp; Transcription |
| Estall, Jennifer | Institut de recherches cliniques de Montréal Université de Montréal |
Sub fonct -AP :Fonds de démarrage de INMD (Fin trans pour cliniciens & nou cher) | Transcriptional regulators of beta-cell health, function, and diabetes | Apoptosis; Beta-Cells; Glucose Homeostasis; Immune Cells; Inflammation; Insulin; Metabolism; Pgc-1; Polymorphism; Transcriptional Co-Regulators |
| Estall, Jennifer | Institut de recherches cliniques de Montréal Université de Montréal |
Subv de fonct- AP : Fonds de démarrage INMD (finance trans)-nouveaux chercheurs | Transcriptional Regulation of Fatty Liver Disease | Biomarker; Fatty Liver Disease; Fibrosis; Inflammation; Insulin Resistance; Metabolism; Mitochondria; Pgc-1alpha; Reactive Oxygen Species; Transcription |
| Eurich, Dean | University of Alberta | Subvention Projet | Reorganizing the Approach to Diabetes through the Application of Registries (RADAR) | Diabetes; First Nations; Health Outcomes; Intervention |
| Eurich, Dean | University of Alberta | Subvention de fonctionnement | International Population-Based Evaluation of Drug Therapies Used to Manage Type 2 Diabetes | Cardiovascular System; Diabetes; Health Outcomes; Mortality; Pharmacotherapy; Population Health |
| Eurich, Dean | University of Alberta | Subvention de fonctionnement | The Impact of Drug Exposure Misclassification on Study Estimates of Clinical Outcomes in Administrative Drug Databases | Health Outcomes; Pharmacotherapy; Policy; Population Health |
| Eurich, Dean | University of Alberta | Subvention de fonctionnement | Effectiveness of Sitagliptin in Patients with Diabetes and Heart Failure: Population Based Cohort Study | Diabetes; Drug Therapy; Health Services; Heart Failure; Mortality |
| Ezzat, Shereen Z | University Health Network (Toronto) University of Toronto |
Subvention de fonctionnement | Fibroblast Growth Factor Receptor 4 in Endocrine Homeostasis | Cell Growth; Endocrine Tumors; Endocrinology; Hormone Regulation |
| Fantus, Ivan G | Research Institute of the McGill University Health Centre/Institut de recherche du Centre universitaire de santé McGill McGill University/Université McGill |
Subvention Projet | Novel mediators of thioredoxin-interacting protein in diabetes complications. | Diabetes Mellitus; Diabetic Nephropathy; Kidney Disease |
| Fantus, Ivan G | University Health Network (Toronto) University of Toronto |
Subv de fonct - AP : fonds de démarrage de l'INMD (financement provisoire) | The role of TxNIP in the development of diabetic nephropathy. | Diabetes Complications; Diabetic Nephropathy; High Glucose; Mesangial Cells; Nadph; Oxidase; Oxidative Stress; Reactive Oxygen Species (Ros); Thioredoxin-Interacting Protein (Txnip) |
| Fantus, Ivan G | Toronto General Hospital University of Toronto |
Subvention de fonctionnement | Interactions between cGMP and insulin cell signaling pathways: Physiology and molecular mechanisms of regulation of insulin sensitivity. | Adipocytes; Glucose Uptake; Insulin Resistance; Insulin Signaling; Type 2 Diabetes Mellitus; Tyrosine Phosphatase |
| Fantus, Ivan G | University Health Network (Toronto) University of Toronto |
Subvention de fonctionnement | Tyrosine kinase signaling in the pathogenesis of diabetic nephropathy. | Albuminuria; Glucose Metabolism; Metabolism; Proteins; Tyrosine Kinase |
| Faraj, May | Institut de recherches cliniques de Montréal Université de Montréal |
Subv de fonct-AP : fonds de démarrage INMD (financement trans) -cliniciens | ApoB-lipoproteins, adipose tissue NLRP3 inflammasome and insulin resistance | 12 Weeks Omega-3 Fatty Acids-Rich Diet; In Vivo And And Ex Vivo Human And Mice Models; Innate Immunity And Nlrp3 Inflammasome; Insulin Sensitivity And Secretion; Lipids And Apob-Lipoproteins; Overweight And Obese Subjects; Postprandial Fat Clearance; Stable And Radioactive Isotope Tracing; White Adipose Tissue Function |
| Faraj, May | Institut de recherches cliniques de Montréal Université de Montréal |
Subvention de fonctionnement | The inflammasome and dysfunctional adipose tissue: why should apoB-lipoproteins be targeted in humans | 16 Wks Omega-3 Fatty Acids Supplementation; Clinical Study In Obese Subjects; In Vivo And And Ex Vivo Models; Innate Immunity And Nlrp3 Inflammasome; Insulin Sensitivity And Secretion; Lipoprotein Metabolism; Postprandial Dietary Fat Clearance; Stable And Radioactive Isotope Tracing; White Adipose Tissue Function |
| Faraj, May | Institut de recherches cliniques de Montréal Université de Montréal |
Subvention de fonctionnement | Targeting hyperapoB vs normoapoB to reduce the risk of type 2 diabetes in obese subjects; mechanism of action | 24 Weeks Hypocaloric Diet Intervention; Blood & Adipose Tissue); Fatty Acid Trapping (In Vivo & Ex Vivo In Adipose Tissue); Inflammation (In Vivo & Ex Vivo; Insulin Sensitivity (In Vivo & Ex Vivo In Adipose Tissue); Lipids & Apob-Lipoproteins (Size; Number & Oxidation); Obese Subjects With High Versus Low Serum Apob100 |
| Faraj, May | Institut de recherches cliniques de MontréalUniversité de Montréal | Subvention Projet | White adipose tissue LDL receptors and omega-3 as modulators of the risk for type 2 diabetes | Chronic Inflammation And Innate Immunity; Clinical And Basic Studies; Insulin Secretion And Sensitivity; Ldlr And Cd36; Lipoprotein Metabolism; Macrophages; Nlrp3 Inflammasome; Pcsk9; Type 2 Diabetes; White Adipose Tissue |
| Faulkner, Guy | University of Toronto | Subvention de fonctionnement | Identifying and Measuring Correlates and Determinants of Physical Activity in Individuals with Schizophrenia | Accelerometry; Correlates; Determinants; Epidemiology; Intervention; Obesity; Physical Activity; Schizophrenia |
| Faulkner, Guy | University of Toronto | Subvention de fonctionnement - Annonce de priorités : obésité | Identifying and Measuring Correlates and Determinants of Physical Activity in Individuals with Schizophrenia | Accelerometry; Correlates; Determinants; Epidemiology; Intervention; Obesity; Physical Activity; Schizophrenia |
| Feig, Denice S | Lunenfeld-Tanenbaum Research Institute (Toronto) University of Toronto |
Subvention Projet | Metformin in Women with Type 2 Diabetes in Pregnancy (MiTy) Trial: A randomized controlled trial | Diabetes In Pregnancy; Metformin; Pregnancy Outcomes; Randomized Controlled Trial; Type II Diabetes |
| Feig, Denice S | Sinai Health System (Toronto) University of Toronto |
Subvention de fonctionnement | The MiTY Trial (Metformin in Women with Type 2 Diabetes in Pregnancy) | Pregnancy; Randomized Controlled Trial; Type 2 Diabetes |
| Feig, Denice S | Sinai Health System (Toronto) University of Toronto |
Subvention de fonctionnement | MiTy Kids (Metformin in Women with Type 2 Diabetes in Pregnancy Kids Trial) | Childhood Obesity; Pregnancy; Type 2 Diabetes |
| Feig, Denice S | Sinai Health System (Toronto) University of Toronto |
Subvention Projet | MiTy: Metformin in Women with Type 2 Diabetes in Pregnancy: A randomized controlled trial. | Diabetes In Pregnancy; Metformin; Pregnancy Outcomes; Randomized Control Trial; Type II Diabetes |
| Ferguson, Alastair V | Queen's University (Kingston, Ontario) | Subvention de fonctionnement | The Subfornical Organ - A critical central nervous system sensor and integrator of metabolic, cardiovascular and immune signals in the circulation. | Camp; Central Autonomic Control; Cholecystokinin; Circumventricular Organs; Gene Expression; Hypertension; Insulin; Obesity; Patch Clamp Electrophysiology |
| Fernyhough, Paul | University of Manitoba | Subvention de fonctionnement - AP: Programme de partenariats régionaux: Manitoba | Muscarinic receptor antagonism as a novel mechanism for sensory nerve repair. | Animal Models; Chemotherapy-Induced Neuropathy; Confocal Imaging; In Vivo Electrophysiology; Mitochondria; Muscarinic Receptors; Nerve Regeneration; Pain Sensitivity; Peripheral Neuropathy; Sensory Neuron |
| Ferro, Mark | University of Waterloo (Ontario) | Subvention Projet | Multimorbidity in Children and Youth Across the LIFEcourse (MY LIFE) | Child/Adolescent Health; Children And Adolescents; Cohort Study; Health Service Use; Health Trajectories; Multilevel Modeling; Multimorbidity; Physical Activity; Physical And Mental Health |
| Ferron, Mathieu | Institut de recherches cliniques de Montréal Université de Montréal |
Subvention de fonctionnement | Role of vitamin K-dependent gamma-carboxylation in glucose metabolism | Bone; Diabetes; Gamma-Carboxylation; Glucose Metabolism; Insulin; Islets; Obesity; Osteoblasts; Osteocalcin; Vitamin K |
| Filion, Kristian B | Lady Davis Institute for Medical Research (Mtl) McGill University/Université McGill |
Subvention Projet | Incretin-based Drugs and the Risk of Adverse Renal Outcomes | Acute Kidney Injury; Database; Dpp-4 Inhibitors; Drug Safety; Epidemiology; Glp-1 Analogs; Incretin-Based Drugs; Kidneys; Pharmacoepidemiology; Type 2 Diabetes |
| Filion, Kristian B | CIUSSS de Centre-Ouest-de-l'Ile-de-Montréal-Jewish General/CIUSSS de Centre-Ouest-de-l'Ile-de-Montréal-Hôpital juif McGill University/Université McGill |
Subvention de fonctionnement | Gestational Diabetes Mellitus and the Risk of Incident Cardiovascular Disease | Cardiovascular Disease; Database; Epidemiology; Gestational Diabetes; Myocardial Infarction; Pregnancy; Risk Stratification; Stroke |
| Forster, Alan J | Ottawa Hospital Research Institute/Institut de recherche de l'Hôpital d'Ottawa University of Ottawa/Université d'Ottawa |
Subvention de fonctionnement | Information systems-enabled outreach program for Adverse Drug Events | Adherence; Health Services Research; Information Technology; Patient Safety; Pharmacoepidemiology |
| Fortier, Isabel | Research Institute of the McGill University Health Centre/Institut de recherche du Centre universitaire de santé McGill McGill University/Université McGill |
Subvention de fonctionnement: Registre des cohortes canadiennes sur les ODSM | Research Advancement through Cohort Cataloguing and Harmonization (ReACH) | Cohorts; Data Discovery; Data Harmonization/Integration; Developmental Origins Of Health And Diseases; Early Life Trajectories; Metadata Catalogue; Open Source Software Development; Pregnancy/Birth Cohorts |
| Fraser, Graham M | Memorial University of Newfoundland | Subvention Projet | Microvascular Blood Flow Regulation and Insulin Resistance in an Animal Model of Type 2 Diabetes | Capillary Blood Flow; Endothelial Function; Glucose Uptake; Hyperglycaemia; Insulin Resistance; Mass Transport; Mathematical Modelling; Microcirculation; Microvascular Blood Flow Regulation; Type 2 Diabetes |
| Fraser, Paul E | University of Toronto | Programme de démonstration des principes - phase I | Amyloid-Based Therapies for Type 2 Diabetes | Beta Cells; Diabetes; Islet Amyloid; Peptide Chemistry; Pharmacokinetics |
| Fulton, Stephanie | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention Projet | Targeting alpha-beta-hydrolase domain 6 in the neural control of body weight, reward and mood | Endocannabinoids; Energy Expenditure; Feeding; Gaba; Mood; Motivation; Neuropharmacology; Nucleus Accumbens; Obesity; Reward |
| Gaisano, Herbert Y | University of Toronto | Subvention Projet | Novel excitosomes mediating exocytosis in neuroendocrine cells | Calcium Channels; Electrophysiology; Exocytosis; Insulin Granule Exocytosis; Islet Beta Cells; Potassium Channels; Reserve Pool; Snare Proteins; Tirf-Sim Microscopy |
| Gaisano, Herbert Y | University of Toronto | Subvention de fonctionnement | Rescuing the insulin exocytotic defects in type 2 diabetes | Cytoskeleton; Diabetes; Evanescent Microscopy; Insulin Exocytosis; Lentivirus; Multiphoton Microscopy; Patch Clamp Electrophysiology; Snare Proteins |
| Gaisano, Herbert Y | University of Toronto | Subvention Projet | Role of autophagy dysregulation in pancreatitis caused by alcohol and glucagon-like peptide | Alcoholic Pancreatitis; Autophagy; Glp-1 Induced Pancreatitis; Human Pancreas; Snare Proteins |
| Gaisano, Herbert Y | University of Toronto | Subvention de fonctionnement | Mechanisms of pancreatitis elucidated on human pancreas in situ | Alcoholic Pancreatitis; Glucagon Like Peptide 1; Human Pancreas; Pathologic Exocytosis; Snare Proteins |
| Gaisano, Herbert Y | University of Toronto | Subvention de fonctionnement | Rescuing insulin exocytotic defects in type 2 diabetes | Cytoskeleton; Diabetes; Evanescent Microscopy; Insulin Exocytosis; Lentivirus; Multiphoton Microscopy; Patch Clamp Electrophysiology; Snare Proteins |
| Gaisano, Herbert Y | University of Toronto | Subvention de fonctionnement | SNARE regulation of potassium channels in neuroendocrine cells | Diabetes; Evanescent Microscopy; Exocytosis; Pancreatic Islet; Patch Clamp; Potassium Channels |
| Galloway, Tracey L | University of Toronto | Subv de fonct - AP : santé des Premières nations, des Inuits et/ou des Métis | The impact of proposed change in federal health funding policy on health programs operating in Yukon First Nations communities | Aboriginal Health; Community Health; Disease Prevention; Health Policy; Health Programs; Maternal-Child Health; Nutrition; Physical Activity; Population Health; Public Health |
| Gamble, John-Michael | University of Waterloo (Ontario) | Subvention Projet | Comparative Safety of the Sodium Glucose Co-transporter-2 (SGLT-2) Inhibitors in Patients with Type 2 Diabetes | Antidiabetic Medications; Database Analysis; Diabetes Mellitus; Drug Safety; Health Outcomes; Observational Study; Pharmacoepidemiology; Population Health |
| Gamble, John-Michael | Memorial University of Newfoundland | Subvention de fonctionnement | Comparative Safety and Effectiveness of the Incretins | Cohort Study; Comparative Effectiveness Research; Database Analysis; Diabetes; Drug Safety And Effectiveness; Health Outcomes; Pharmacoepidemiology; Population Health |
| Garcia Bengoechea, Enrique | McGill University/Université McGill | Subvention de fonctionnement : des connaissances à la pratique | Participatory Policy Intervention to Promote School-Based Physical Activity | Aboriginal Health; Community Health; Community-Based Participatory Research; Health Promotion; Implementation Study; Integrated Knowledge Translation; Physical Activity Intervention; Policy Intervention; School-Based Intervention |
| Gaudet, Laura M | Ottawa Hospital Research Institute/Institut de recherche de l'Hôpital d'Ottawa University of Ottawa/Université d'Ottawa |
Subv d'équipe: Équipes cliniciens pour rech. en obs. & médecine materno-fœtale | OaK 2016-2021: Investigating Contemporary Topics in OB/MFM | Assisted Reproductive Technology; Obesity; Pregnancy; Triage Tool |
| Gaudreau, Pierrette | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention de fonctionnement | Deciphering the characteristics and functions of a novel growth hormone-releasing hormone receptor in the kidney | Cell Proliferation; Cell Signaling; Cell Survival; In Vivo Studies; Kidney; Rat Models; Receptor Characterization; Renal Cell Culture |
| Geraldes, Pedro M | Université de Sherbrooke | Subvention Projet | Mechanisms of insulin resistance in podocytes and diabetic nephropathy | Diabetic Nephropathy; Insulin; Insulin Receptor; Phosphatase; Podocytes; Protein Kinase C |
| Geraldes, Pedro M | Université de Sherbrooke | Subvention de fonctionnement | Role of SHP-1 in poor collateral vessel formation and angiogenic response in diabetes. | Angiogenesis; Collateral Vessel Formation; Diabetes; Endothelial Cells; Pdgf; Peripheral Arterial Disease; Phosphatase; Shp-1; Smooth Muscle Cells; Vegf |
| Geraldes, Pedro M | Université de Sherbrooke | Subvention de fonctionnement | New mechanisms of podocyte injury in diabetic nephropathy | Diabetic Nephropathy; Epigenetics; Insulin; Insulin Resistance; Mtor; Nephrin; Podocytes; Protein Kinase C; Shp-1; Vegf |
| Geraldes, Pedro M | Université de Sherbrooke | Subvention Projet | Phosphatases and mechanisms of poor collateral vessel formation in diabetes | Angiogenesis; Diabetes; Endothelial Cells; Limb Ischemia; Pdgf; Phosphatase; Vegf |
| Giacca, Adria | University of Toronto | Subvention Projet | Hepatic signalling of glucose and lipid metabolism in vivo | Diabetes; Free Fatty Acids; Hyperinsulinemic Clamp; In Vivo; Inflammation; Insulin Resistance; Lipotoxicity; Liver; Obesity; Tracer Methodology |
| Giacca, Adria | University of Toronto | Subvention de fonctionnement | Novel mediators of beta-cell lipotoxicity | Beta Cell; Diabetes; Free Fatty Acids; Hyperglycemic Clamp; In Vivo; Inflammation; Lipotoxicity; Obesity; Oxidative Stress; Sirtuins |
| Giacca, Adria | University of Toronto | Subvention Projet | The role of NOD1 in obesity-associated diabetes | Damage Associated Molecular Patterns; Fat; Innate Immunity; Pattern Recognition Receptors |
| Gibson, William T | University of British Columbia | Subvention de fonctionnement | Rare Obesity Disorders Informing Common Disease | Extreme Phenotypes; Genomics; Health Of Vulnerable Populations(Children With Disabilities); Mechanisms Shared Between Common And Rare Diseases; Obesity And Diabetes |
| Gibson, William T | University of British Columbia | Subv de fonct - AP : fonds de démarrage de l'INMD (financement provisoire) | Rare Obesity Disorders Informing Common Disease | Extreme Phenotypes; Genomics; Health Of Vulnerable Populations(Children With Disabilities); Mechanisms Shared Between Common And Rare Diseases; Obesity And Diabetes |
| Gibson, William T | BC Children's Hospital Research Institute University of British Columbia |
Subvention Projet | Regulation of islet cell proliferation by p300 | Beta Cell; Glucose Tolerance; Mouse Models Of Human Disease; P300; Transcriptional Coactivators |
| Gibson, William T | BC Children's Hospital Research Institute University of British Columbia |
Subvention Projet | Insights from Rare Overgrowth Syndromes for Common Diseases | Cancer; Congenital Anomalies; Dna Methylation; Exome Sequencing; Histone Acetyltransferases; Histone Methyltransferases; Intellectual Disability; Obesity; Overgrowth; Rare Diseases |
| Gignac, Monique A | Institute for Work & Health (Toronto) University of Toronto |
Subvention de fonctionnement | Employment needs and experiences of workers with arthritis and diabetes: Keeping the Boom(ers) in the labour market. | Aging; Arthritis; Baby Boomers; Chronic Episodic Health Conditions; Diabetes; Employment; Older Workers; Psycholsocial Factors |
| Giguere, Vincent | McGill University/Université McGill | Subvention de fonctionnement | Transcriptional control of metabolism by the estrogen related receptors (ERRs) | Diabetes; Functional Genomics; Metabolism; Molecular Biology; Nuclear Receptors; Transcription |
| Giguere, Vincent | McGill University/Université McGill | Subvention de fonctionnement | The ERR pathway: control of energy metabolism and its implication in metabolic disorders | Diabetes; Functional Genomics; Gene Expression; Lipid Disorders; Metabolism; Metabolomics; Micro Rna; Mouse Models; Obesity |
| Gilbert, Richard E | St. Michael's Hospital (Toronto) University of Toronto |
Subvention de fonctionnement | The Role of Sirtuin1 in Diabetic Nephropathy: Experimental and Clinical Studies | Diabetes; Humans; Kidney Disease; Mice |
| Gilliland, Jason A | University of Western Ontario | Subvention Projet | Development and Evaluation of a Smartphone Based Program for Improving Food Literacy and Healthy Eating Among Youth | Behaviour Change; Child And Youth Health; Dietary Behaviours; Food Environments; Food Literacy; Healthy Eating; Nutritional Messaging; Overweight/Obesity; Smartphones; Surveys |
| Gilliland, Jason A | University of Western Ontario | Subvention Projet | Evaluation of a Smartphone Based Intervention for Improving Food Literacy, Food Purchasing, and Diet Quality Among Youth in Urban, Suburban, and Rural Environments | Behaviour Change; Child And Youth Health; Dietary Behaviours; Food Environments; Food Literacy; Healthy Eating; Nutritional Messaging; Overweight/Obesity; Smartphones; Surveys |
| Gilron, Ian | Queen's University (Kingston, Ontario) | Essais contrôlés randomisés | Combination pharmacotherapy for the management of pain (2008) | Analgesic Pharmacology; Anticonvulsants; Antidepressants; Chronic Pain; Clinical Pharmacology; Controlled Trials; Diabetic Neuropathy; Drug Combinations; Neuropathic Pain; Opioids; Pain; Pain Measurement; Randomized |
| Williams, Jason | Nova Scotia Health Authority (Halifax) | Programme de démonstration des principes - phase II | The Production of Decellularized Human Skin to Treat Chronic Diabetic Ulcers | Chronic Wounds; Decellularized Dermis; Diabetes; Diabetic Ulcer; Human Trial; Tissue Engineering; Wound Healing |
| Glazner, Gordon W | St. Boniface General Hospital Research Centre (Winnipeg) University of Manitoba |
Subv. de fonct -AP : Inst. de la Nutrition, métabolisme, diabète -fin transit. | Targeting the cytokine/NF-kB axis in diabetic neuropathy | Cytokine; Diabetic Neuropathy; Mitochondria; Neurotrophic Factors; Nf-Kappab; Oxidative Stress |
| Glazner, Gordon W | St. Boniface General Hospital Research Centre (Winnipeg) University of Manitoba |
Subvention de fonctionnement - AP: Programme de partenariats régionaux: Manitoba | Targeting the cytokine/NF-kB axis in diabetic neuropathy | Cytokine; Diabetic Neuropathy; Mitochondria; Neurotrophic Factors; Nf-Kappab; Oxidative Stress |
| Godwin, Marshall S | Memorial University of Newfoundland | Subvention de fonctionnement | Health Coaching to Effect Lifestyle Behaviour Change: A Randomized Trial of Individuals with Pre-disease | Cardiovascular Disease; Cardiovascular Lifestyle; Lifestyle Modification; Nurse Coaching; Pre-Disease |
| Gramolini, Anthony O | University of Toronto | Subvention de fonctionnement | Modeling cardiovascular development using human stem cells | Cardiac Development; Cardiac Progenitors; Cell Biology; Cell Surface; Mass Spectrometry; Proteomics; Stem Cells |
| Grant, Michael D | Memorial University of Newfoundland | Subv de fonct - AP : VIH/Sida Financement provisoire - Volet biomédical/clinique | Cytomegalovirus Immune Memory Inflation and Immunosenescence in Human Immunodeficiency Virus Infection | Age-Related Morbidity; Cytomegalovirus; Hiv Infection; Immune Suppression; Immunosenescence; Memory Inflation; Trec Assay |
| Grant, Michael D | Memorial University of Newfoundland | Subv de fonct. - AP: Programme de partenariats régionaux-Terre Neuve et Labrador | Cytomegalovirus Immune Memory Inflation and Immunosenescence in Human Immunodeficiency Virus Infection | Age-Related Morbidity; Cytomegalovirus; Hiv Infection; Immune Suppression; Immunosenescence; Memory Inflation; Trec Assay |
| Greenblatt, Jack F | University of Toronto | Subvention Projet | Mechanisms of gene regulation by the human C2H2 zinc finger proteins and interacting RNAs | C2h2 Zinc Finger Proteins; Chia-Pet; Chip-Sequencing; Clip-Sequencing; Dna Looping; Lumier; Net-Sequencing; Protein-Protein Interactions; Protein-Rna Interactions; Rna Polymerase II |
| Greenwood, Carol E | Baycrest Centre for Geriatric Care (Toronto) University of Toronto |
Subvention de fonctionnement | Neurocognitive Correlates of Hypertension and Type 2 Diabetes in Older Adults | Adaptive Responses; Brain Aging; Cognitive Function; Fmri; Hypertension; Type 2 Diabetes Mellitus |
| Grimshaw, Jeremy M | Ottawa Hospital Research Institute/Institut de recherche de l'Hôpital d'Ottawa University of Ottawa/Université d'Ottawa |
Subvention de fonctionnement | Seeing the forests and the trees - Innovative approaches to exploring heterogeneity in systematic reviews of complex knowledge translation interventions to enhance policy decision making | Complex Interventions; Knowledge Translation; Meta-Subsets Analysis; Patient Care And Outcomes; Policy Decision Making; Quality Improvement Interventions |
| Volchuk, Allen O | University Health Network (Toronto) | Subvention de fonctionnement | The Endoplasmic Reticulum Stress Response in Pancreatic Beta-Cells | Animal Models; Cellular Stress Response; Endoplasmic Reticulum Stress; Pancreatic Beta Cells; Primary Cultured Cells; Type 2 Diabetes |
| Grundberg, Elin | McGill University/Université McGill | Subvention Fondation | Understanding etiology of metabolic diseases by integrative genomics and epigenomics approaches | Epigenetics; Next-Generation Sequencing; Obesity; Type 2 Diabetes |
| Gruneir, Andrea | Women's College Hospital (Toronto) University of Toronto |
Subvention de fonctionnement | Repeat Emergency Department Visits Among Long-Term Care Residents in Ontario | Emergency Department Visits; Linked Administrative Data; Long-Term Care; Older Adults; Repeat Events Models; Transitions |
| Gucciardi, Enza | Ryerson University (Toronto) | Subvention de fonctionnement | Mobile Diabetes Education Teams in Primary Care | Coordinated And Integrated Care; Diabetes Care; Diabetes Education Programs; Diabetes Self-Management Education; Health Services; Implementation And Evaluation; Interprofessional Collaboration; Patient Care Processess; Primary Care Physicians; Qualitative; Quantitative |
| Gutkowska, Jolanta | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention de fonctionnement | Pleiotropic effects of oxytocin | (Ot); Cardioprotection; Cell Differentiation; Diabetes; Glucose Uptake; Heart; Ot Elongated Form- (Ot-Gkr); Oxytocin |
| Gutkowska, Jolanta | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention de fonctionnement | The role of brain natriuretic peptide and oxytocin in prevention of metabolic and cardiovascular complications in diabetes. | Diabetes; Natriuretic Peptides; Oxytocin; Treatment |
| Haas, Tara L | York University (Toronto, Ontario) | Subvention de fonctionnement | Microvascular remodeling of the adipose and muscle tissues in diet-induced obesity: regulation by FoxO proteins | Angiogenesis; Capillaries; Extracellular Matrix; Transcriptional Regulation |
| Haddad, Pierre S | Université de Montréal | Subv de fonct - AP: Appl « double regard » en santé autochtone | The best of both worlds: Developing strategies to provide safe and culturally appropriate access to Traditional Medicines for diabetes care in contemporary Aboriginal primary healthcare. | Aboriginal Health; Health Services; Primary Community Health Care; Traditional Medicine |
| Haddad, Pierre S | Université de Montréal | Équipe de recherche sur la mise en œuvre des Voies de l'équité - composante 2 | Uniting Traditional Ways and Science around medicinal plants/foods for the better prevention and management of Type 2 Diabetes in Canadian First Nations | Aboriginal Health; Community Workshops; Cultural Relevant Physical Cctivities; Diabetes; Foods; Medicinal Plants; Participatory Community Based Research; Public Health Policies; Safety And Efficacy Of Medicinal Plants; Traditional Knowledge |
| Hahn, Margaret | Centre for Addiction and Mental Health (Toronto)/Centre de toxicomanie et de santé mentale University of Toronto |
Subvention Projet | Unraveling the role of central insulin action in relation to glucose abnormalities in first-time antipsychotic users | Antipsychotics; Cognition; Diabetes; Psychosis |
| Hajek, Tomas | Nova Scotia Health Authority (Halifax) Dalhousie University (Nova Scotia) |
Subvention de fonctionnement | Is type 2 diabetes mellitus a risk factor for neuroanatomical changes, cognitive impairment and oxidative stress in bipolar disorders? | Bipolar Disorders; Brain Imaging; Cognitive Testing; Peripheral Biomarkers; Type 2 Diabetes Mellitus |
| Hammond, David G | University of Waterloo (Ontario) | Subv de fonctionnement : rech interventionnelle en santé des populations | Nutritional labeling on menus in Canada and the United States: Evidence to inform policy. | Health Behaviour; Health Policy; Labelling; Nutrition; Obesity Prevention; Policy Evaluation |
| Hammond, David G | University of Waterloo (Ontario) | Subvention Projet | International food policy study: Evaluating the impact of food labelling, marketing, and fiscal nutrition policies. | Diet; Food Policy; Health Behaviour; Nutrition |
| Hammond, Geoffrey L | University of British Columbia | Subvention de fonctionnement | Sex hormone-binding globulin: beyond the plasma transport of sex steroids. | Androgen; Estrogen; Genetic Polymorphisms; Molecular And Cell Biology; Reproduction; Sex Hormone-Binding Globulin; Transcription; Transgenic Mouse; Type 2 Diabetes |
| Han, Victor Khin M | University of Western Ontario | Subvention de fonctionnement | Placental mesenchymal stem cells in regenerative therapy | Cell Signaling; Cerebral Ischemia; Diabetes; Insulin-Like Growth Factors; Mesenchymal Stem Cells; Placenta; Regenerative Therapy; Tissue Environment; Tumorigenesis; Umbilical Cord Blood |
| Hanley, Anthony J | University of Toronto | Subvention de fonctionnement | Understanding the effects of social, behavioural and metabolic factors on early childhood growth trajectories among Aboriginal Canadians | Aboriginal Health; Breast Feeding; Diabetes Mellitus (Type 2); Epidemiology; Infant And Child Growth; Nutrition; Overweight; Population Health |
| Hanley, Anthony J | University of Toronto | Subv de fonct - AP : santé des Premières nations, des Inuits et/ou des Métis | Understanding the Importance of Newly Identified Diabetes Risk Factors among Aboriginal Canadians: The Sandy Lake Health and Diabetes Project | Aboriginal Health; Diabetes Mellitus (Type 2); Epidemiology; Infant Growth; Population Health; Vitamin D |
| Hanley, Anthony J | University of Toronto | Subvention de fonctionnement | Plasma non-esterified fatty acids and the progression of insulin resistance and pancreatic beta-cell dysfunction: a novel targeted omics approach. | Beta Cell Dysfunction; Diabetes Mellitus; Insulin Resistance; Non-Esterefied Fatty Acids; Type 2 |
| Hanning, Rhona M | University of Waterloo (Ontario) | Équipe de recherche sur la mise en œuvre des Voies de l'équité - composante 2 | Refining a Scaling Up Strategy for Bringing Local Healthy Food to School through Learning Circles in First Nations and Métis Communities | Community Capacity Building; Culture; First Nations; Food Systems; Healthy Eating; Knowledge Translation And Exchange; Metis; Scaling Up; Social Capital |
| Haqq, Andrea M | University of Alberta | Subvention de fonctionnement | Evaluation of autonomic nervous system function, body fat distribution and metabolic profile in children with PWS. | Adipocytokines; Autonomic Nervous System; Body Composition; Childhood Obesity; Hormones; Nutrition; Pediatrics; Prader-Willi Syndrome; Visceral Fat |
| Harper, Mary-Ellen | University of Ottawa/Université d'Ottawa | Subvention de fonctionnement | Mitochondrial Uncoupling in Skeletal Muscle: Molecular Mechanisms to Whole Body Implications | Mitochondria; Muscle; Obesity; Reactive Oxygen Species; Type 2 Diabetes Mellitus; Uncoupling Proteins |
| Harper, Mary-Ellen | University of Ottawa/Université d'Ottawa | Subvention Fondation | Mitochondrial Bioenergetics and Redox Biology in Obesity and Related Disease | Bioenergetics; Diet; Exercise; Metabolic Programming; Mitochondria; Mitochondrial Disorders; Oxidative Stress; Protein Post-Translational Modification; Reactive Oxygen Species; Redox Reactions |
| Harris, Stewart B | University of Western Ontario | Subv. de fonct.: Environ. réseau pour la recherche sur la santé des Autochtones | Indigenous Network for Health Advancement | Chronic Disease; Community-Based Participatory Research; Diabetes Mellitus; Environmental Dispossession; Food Environments; Indigenous Wellness; Quality Improvement; Traditional Food Systems |
| Hawker, Gillian A | Women's College Hospital (Toronto) University of Toronto |
Subvention Projet | Development & Piloting of a Patient and Provider-Level Behavior Change Intervention to Increase Physical Activity in People with Diabetes through Diagnosis and Management of Concomitant Knee Osteoarthritis | Diabetes; Knee Osteoarthritis; Patient Oriented Research; Physical Activity; Physiotherapy; Primary Care; Quality Of Care; Specialty Care |
| Hayden, Michael R | BC Children's Hospital Research Institute University of British Columbia |
Subvention de fonctionnement | microRNA regulation of ABCA1 and its impact on beta cell function | Abca1; Beta Cells; Cholesterol; Diabetes; Microrna; Mouse Models |
| Hebert, Richard L | University of Ottawa/Université d'Ottawa | Subvention de fonctionnement | Tubular dysfunction in diabetes: role of PGE2/EP receptors | Apoptosis; Cell Growth; Diabetic Nephropathy; Ep1 Knockout Mouse; Fibrosis; Fvb And Diabetic (Ove-26) Mouse Model; Isolated Perfused Mouse Cortical Collecting Duct; Isolated Perfused Mouse Proximal Tubules; Sodium Transport; Water Flow |
| Hegele, Robert A | University of Western Ontario | Subvention Fondation | Clinical translation of genomic understanding of cardiometabolic risk | Atherosclerotic Cardiovascular Disease; Cardiometabolic Risk; Diabetes; Dyslipidemia; Human Genetics And Genomics; Investigational Therapies; Molecular Diagnosis; Next Generation Dna Sequencing; Obesity; Risk Factors |
| Hegele, Robert A | University of Western Ontario | Subvention de fonctionnement | Genetic architecture of cardiometabolic risk in families and communities. | Atherosclerosis; Diabetes; Genetic Association Analysis; Lipids; Metabolic Syndrome; Risk Factors |
| Henderson, Melanie | Centre hospitalier universitaire Sainte-Justine Université de Montréal |
Subvention Projet | Linking lifestyle behaviors, microbiota & cardiometabolic health from childhood to early adulthood: The QUALITY Cohort. | Cardiovascular Disease Risk; Diet; Fitness; Gut Microbiota; Obesity; Oral Microbiota; Physical Activity; Sedentary Behaviours; Type 2 Diabetes |
| Lambert, Marie | Centre hospitalier universitaire Sainte-Justine Université de Montréal |
Subvention de fonctionnement | Towards the prevention of type 2 diabetes: improving our understanding of longitudinal changes in glucose homeostatis in youth | Adolescent; Cardiometabolic Risk Factors; Cohort Study; Impaired Fasting Glucose; Impaired Glucose Homeostasis; Impaired Glucose Tolerance; Obesity; Type 2 Diabetes |
| Hirasawa, Michiru | Memorial University of Newfoundland | Subvention Projet | Mechanism for high fat diet-induced activation of MCH neurons and its role in obesity | Energy Homeostasis; Food Intake; High Fat Diet; Hypothalamus; Inflammation; Melanin Concentrating Hormone; Obesity; Prostaglandin |
| Hivert, Marie-France | Université de Sherbrooke | Subv de fonct - AP : fonds de démarrage de l'INMD (financement provisoire) | Evaluation of contributing heritable and environmental factors to adipokine and glycemic regulation variability during pregnancy and fetal development. | Adipokines; Epidemiology; Epigenetic; Fetal Development; Gestational Diabetes; Glucose Regulation; Heritable Risk Factors; Insulin; Prospective Cohort; Quantitative Traits |
| Hoffman, Brad G | University of British Columbia | Subvention Projet | Determining the role of histone modifications in mediating transcriptional consistency in beta-cells and in diabetes pathogenesis | Beta-Cell; Chromatin Structure; Diabetes; Histone Modifications; Transcriptional Regulation; Trithorax Complex |
| Hoffman, Brad G | BC Children's Hospital Research Institute University of British Columbia |
Subvention de fonctionnement | Determining Myt3's role in beta-cell maturation, function and inflammatory response. | Apoptosis; Diabetes; Gene Regulation; Glucose-Stimulated Insulin Secretion; Transcription Factors |
| Holloway, Alison C | McMaster University | Subvention Projet | E-cigarette use during pregnancy: Impact on metabolic health of the offspring | Dysmetabolism; E-Cigarettes; Early Life Origins Of Health; Maternal Smoking; Nicotine; Obesity |
| Holloway, Alison C | McMaster University | Subvention de fonctionnement | Antidepressant use during pregnancy and the risk of metabolic disturbances in the offspring | Antidepressants; Beta Cell; Fetal Programming Of Adult Disease; Obesity; Pregnancy; Type 2 Diabetes |
| Howell, Doris M | University Health Network (Toronto) University of Toronto |
Partenariats pour l'amélioration du système de santé (PASS) | Integration of a Disease Self-Management Approach in the Cancer System to Optimize Health and Living with Cancer: A Road Map for Implementation | Chronic Disease Self-Management |
| Huff, Murray W | University of Western Ontario | Subvention de fonctionnement | Regulation of intestinal lipoprotein overproduction in insulin resistant states by citrus flavonoids. | Atherosclerosis; Chylomicrons; Dyslipidemia; Flavonoids; Insulin Signaling; Mouse Model Of Insulin Resistance; Obesity; Very Low Density Lipoproteins |
| Hui, Chi-Chung | Hospital for Sick Children (Toronto) University of Toronto |
Subvention de fonctionnement | Irx3 and Irx5 as novel genetic factors controlling energy homeostasis | Adipocyte; Body Mass Index; Diabetes; Energy Homeostasis; Fto; Genetic Mouse Models; Hypothalamus; Iroquois Homeobox Genes; Mass Spectrometry; Obesity |
| Hurley, Jeremiah E | McMaster University | Subvention de fonctionnement: Projection économique | Investing in Primary and Secondary Prevention: Economic Forecasting to Inform Policies Regarding Amortization of Program Costs | Amortization; Autism; Diabetes Prevention; Early Psychosis Intervention; Economic Forecasting; Economics Of Prevention; Health Economics; Innovative Public Finance; Intergenerational Violence; Public Sector Budgeting |
| Husain, Mansoor | Toronto General Research Institute University of Toronto |
Subvention Projet | Cardiovascular effects of GLP-1(28-36): focus on heart failure. | Glucagon-Like Peptide; Heart Failure; Metabolism; Mouse Models Of Disease; Transgenic Mice |
| Hutton, Eileen K | McMaster University | Subvention de fonctionnement | The Baby & Microbiota of the Intestine Project (Baby & Mi) | Antibiotic Exposure; Child Health; Cohort Study; Intestinal Microbiota; Neonatal Health; Obesity; Pregnancy |
| Jacobs, Rene L | University of Alberta | Subvention de fonctionnement | The central role of the vagus nerve in high fat diet-induced obesity | Energy Expenditure; Gene Regulation; High-Fat Diet; Nutrition; Vagus Nerve |
| Jacobs, Rene L | University of Alberta | Subvention Projet | Intestinal phosphatidylcholine synthesis, dietary lipid handling and the metabolic syndrome | Diet-Gene Interaction; High Fat Diet; Intestine; Knockout Mice; Lipoproteins; Phosphatidylcholine |
| Jardine, Cynthia | University of Alberta | Sub fonct: équipe rech la mise en œuvre des voies de l'équité - composantes 1 | Indigenous Youth as Agents of Change for Community Wellness: Promoting Resilience and Positive Youth Development | Health Promotion; Indigenous; Participatory Research; Resilience; Self-Efficacy; Suicide Prevention; Wellness; Youth |
| Jefferies, Wilfred A | University of British Columbia | Subvention de fonctionnement | Characterization of Functional L-Type Calcium Channels in Lymphocytes | Arthritis; Cacna1f; Diabetes; Mouse Models; T-Lymphocyte; Voltage-Gated Calcium Channel |
| Jenkins, David J | University of Toronto | Subvention sur la synthèse des connaissances | Effect of dietary pulses on cardiometabolic risk in humans: A series of systematic reviews and meta-analyses to provide evidence-based guidance for nutrition guidelines development. | Beans; Blood Pressure; Body Weight; Cardiovascular Diease; Chickpeas; Controlled Feeding Trials; Diabetes; Lentils; Meta-Analysis; Metabolic Syndrome; Nutrition; Peas; Systematic Review |
| Jenkins, David J | University of Toronto | Subvention de fonctionnement | The effect of an enhanced dietary portfolio plus exercise on cardiovascular risk in high risk individuals. | Cardiovascular Disease Prevention; Cvd Risk; Diabetes; Diet; Dietary Cholesterol; Feasibility; Functional Foods; Glycemic Index; Inflammatory Biomarkers; Lipid Analysis; Monounsaturated Fat; Nuts; Plant Sterols; Saturated Fat; Vegetable Protein; Viscous Fiber |
| Jenkins, David J | St. Michael's Hospital (Toronto) University of Toronto |
Subv. de fonct. - Le programme de mentorat des essais contrôlés randomisés | Low-Glycemic Index Diet and Other Intervention Trials (RCTs) in Type 2 Diabetes and Cardiovascular Disease | Arterial Damage; Dietary Interventions; Ecoptic Fat; Glycemic Index; Intramyocellular Fat; Magnetic Resonance Imaging (Mri); Obesity; Randomized Controlled Trials; Type 2 Diabetes; Visceral Fat |
| Jenkins, David J | University of Toronto | Essais contrôlés randomisés | Low Glycemic index diet to improve glycemic control and cardiovascular disease in type 2 diabetes | Blood Glucose And Lipid Control; Dietary Intervention; Intima Media Thickness (Imt); Intra Plaque Hemorrhage (Iph); Low Glycemic Index (Gi); Magnetic Resonance Imaging (Mri); Type 2 Diabetes |
| Jenkins, David J | University of Toronto | Sub de fonct : sub rech program. alimentation & la santé -demande détaillée | Canada-Wide Human Nutrition Trialists' Network. | Arterial Plaque; Canadian Network; Cardiovascular Disease; Diabetes; Dietary Trials; Genetics; Knowledge Synthesis And Translation; Magnetic Resonance Imaging And Imaging; Metabolic Syndrome; Obesity |
| Jin, Tianru | University Health Network (Toronto) University of Toronto |
Subvention de fonctionnement | A novel mechanism in controlling the expression of ChREBP and liver lipogenesis | Chramatin Immunoprecipitation (Chip); Chrebp; Insulin Resistance; Liver Lipogenesis; Transcriptional Repression; Transgenic Mice |
| Jin, Tianru | University Health Network (Toronto) University of Toronto |
Subvention Projet | Metabolic functions of the Wnt signaling pathway | Beta-Catenin; Estrogen; Gene Expression; Glp-1; Gluconeogenesis; Insulin; Lipid Metabolism; Tcf7l2; Transgenic Mouse Models; Wnt |
| Johnson, James D | University of British Columbia | Subvention de fonctionnement | Mechanisms of insulin receptor trafficking and signalling in beta-cells | Autocrine Feedback; Caveolin; Endocytosis And Endosomes; High Fat Diet And Lipotoxicity; Hyperinsulinemia; Insulin Receptor Signalling; Insulin Resistance; Pancreatic Islets; Signal Transduction; Type 2 Diabetes |
| Johnson, James D | University of British Columbia | Subvention de fonctionnement | Effects of circulating insulin on metabolism and mammalian longevity | Autophagy And Protein Homeostasis; Extra-Pancreatic Insulin In The Brain; Healthy Aging; Hormonal And Neuronal Control Of Longevity; Insulin As A Tissue Growth Factor; Insulin Resistance And Glucose Homeostasis; Knockout Mouse Models; Mechanisms Of Aging And Longevity; Regulation Of Adipogenesis By Insulin; Regulation Of Lifespan By Diet And Caloric Restriction |
| Johnson, James D | University of British Columbia | Subvention Projet | Regulation of beta-cell proliferation by insulin production workload | Cell Differentiation; Cell Proliferation; Conditional Knockout Mice; Diabetes; Endoplasmic Reticulum Stress; Insulin Synthesis; Lineage Tracing; Pancreatic Beta-Cells; Proteomics; Transcriptomics |
| Johnson, Jeffrey A | University of Alberta | Subvention de fonctionnement | Diabetes, influenza, and cardiopulmonary outcomes: The rationale for targeting influenza vaccinations for patients with diabetes | Diabetes; Influenza Vaccination; Influenza-Like Illness; Seasonal Influenza |
| Johnson, Jeffrey A | University of Alberta | Subvention de fonctionnement | Cancer incidence and glucose lowering therapies for Type 2 Diabetes: Are there differences between agents? | Cancer; Epidemiology; Insulin; Metabolic Syndrome; Oral Hypoglycemic Agents; Type 2 Diabetes |
| Joseph, Jamie W | University of Waterloo (Ontario) | Subvention Projet | Role of prolyl hydroxylase in the regulation of insulin release. | Beta Cells; Insulin Secretion; Islets; Metabolism; Metabolomics; Oxygen Sensing; Pancreas; Transgenic Mice |
| Joseph, Jamie W | University of Waterloo (Ontario) | Subvention de fonctionnement | The role of anaplerosis in glucose-stimulated insulin release. | Diabetes; Insulin Secretion; Islet Function; Metabolism; Molecular Biology; Pancreatic Beta-Cell |
| Jung, Mary E | University of British Columbia | Subvention de fonctionnement | Integrating a brief, social cognitive theory-based intervention with high-intensity interval training to improve exercise adherence | Accelerometer; Behavioural Counseling; Exercise Adherence; Prediabetes; Self-Efficacy; Self-Regulation; Social Cognitive Theory |
| Jung, Mary E | University of British Columbia | Subvention Fondation | Self-Regulation of Exercise Behaviour in Individuals with Prediabetes: From Evidence to Community Implementation | Community Intervention; Continuous Glucose Monitors; Evidence-Based Behaviour Change Techniques; Exercise Adherence; Mobile Health; Prediabetes; Self-Monitoring; Self-Regulation; Self-Regulatory Skills |
| Kaartinen, Mari T | McGill University/Université McGill | Subvention Projet | Role of factor XIII-A and plasma fibronectin in etiology of obesity and type 2 diabetes. | Adipogenesis; Extracellular Matrix; Factor XIII-A; Fat Tissue; Fibronectin; Fibrosis; Insulin Resistance; Obesity; Transglutaminase; Type 2 Diabetes |
| Kaplan, David R | Hospital for Sick Children (Toronto) University of Toronto |
Subvention de fonctionnement | Establishment and maintenance of adult neural stem cell pools | Autism; Brain Aging; Brain Development; Growth Factor; Maternal Diabetes; Maternal Infection; Neural Stem Cell; Proteomics; Senescence; Transgenic Mice |
| Kaplan, Gilaad G | University of Calgary | Subvention de fonctionnement | Preventing Myocardial Infarctions with the Air Quality Health Index | Air Pollution; Air Quality Health Index; Diabetes; Myocardial Infarction |
| Katz, Sherri L | Children's Hospital of Eastern Ontario Research Institute Inc/Institut recherche Centre hospitalier pour enfants de l'est de l'Ontario University of Ottawa/Université d'Ottawa |
Sommeil et les rythmes circadiens : subvention de fonctionnement | Does Treating Obstructive Sleep Apnea in Obese Canadian Youth Improve Blood Sugar Control? A Multi-Centre Prospective Cohort Study. | Cohort Study; Insulin Resistance; Non-Invasive Ventilation; Obesity; Obstructive Sleep Apnea; Pediatric |
| Kaul, Padmaja R | University of Alberta | Subvention de fonctionnement | Gestational Diabetes Mellitus in Alberta | Diagnosis; Gestational Diabetes Mellitus; Pregnancy And Birth Cohort; Rural Urban Differences |
| Kaul, Padmaja R | University of Alberta | Subvention Projet | Impact of maternal diabetes status on adverse neonatal and early childhood outcomes | Early Childhood Outcomes; Maternal Health; Newborn Health; Pregnancy |
| Kaul, Padmaja R | University of Alberta | Subvention de fonctionnement - Analyse secondaire des bases de données | Long-term health outcomes of mothers with gestational diabetes mellitus and their children in Alberta | Child'S Health; Gestational Diabetes Mellitus; Women's Health |
| Kauppinen, Tiina | University of Manitoba | Subvention Projet | Microglia and cognitive impairments in offspring exposed to gestational diabetes mellitus | Cognitive Functions; Conditional Knock Out Mice; Fetal Programming; Gestational Diabetes Mellitus; Hippocampus; Lentivirus Transduction; Microglia; Neurodevelopment; Neuroinflammation; Synapse |
| Kazak, Lawrence | McGill University/Université McGill | Subvention Projet | Physiology and mechanisms of adipocyte creatine energetics | Adipose Tissue; Brown Fat; Ckb; Creatine; Energy Expenditure; Metabolomics; Mitochondria; Mouse Models; Obesity; Thermogenesis |
| Kennedy, Christopher R | Ottawa Hospital Research Institute/Institut de recherche de l'Hôpital d'Ottawa University of Ottawa/Université d'Ottawa |
Subvention de fonctionnement | Prostanoid Signaling in Diabetic Nephropathy | Cell Signaling; Diabetic Nephropathy; Gene-Targeted Mice; Podocyte; Prostanoid Receptors; Proteinuria |
| Kennedy, Christopher R | Ottawa Hospital Research Institute/Institut de recherche de l'Hôpital d'Ottawa University of Ottawa/Université d'Ottawa |
Subvention de fonctionnement | Validating Nox5 as a target for diabetic renal complications | Diabetes; Kidney; Podocyte; Reactive Oxygen Species; Transgenic Mice |
| Kenny, Glen P | University of Ottawa/Université d'Ottawa | Subvention de fonctionnement | Heat stress in older adults and individuals with type 2 diabetes | Aging; Body Heat Storage; Diabetes; Exercise; Heat Stress; Metabolism; Physical Activity; Skin Blood Flow; Sweating; Thermoregulation |
| Khan, Nadia A | St. Paul's Hospital, Vancouver University of British Columbia |
Subvention de fonctionnement | A Culturally Tailored Intervention to Improve Management of Type 2 Diabetes Mellitus in South Asian Patients | A1c; Cultural Barriers; Diabetes; Ethnicity; Peer Intervention; South Asian |
| Khan, Nadia A | St. Paul's Hospital, Vancouver University of British Columbia |
Subvention de fonctionnement | Ethnocultural differences in adherence to pharmacotherapy among Chinese, South Asian and White adults with Type 2 diabetes | Adherence; Administrative Data; Diabetes; Ethnicity |
| Kieffer, Timothy J | University of British Columbia | Subvention Fondation | Hormonal Regulation of Glucose Homeostasis | Beta-Cells; Development; Diabetes; Fgf21; Incretins; Insulin; Islet; Leptin; Obesity; Stem Cells |
| Kieffer, Timothy J | University of British Columbia | Subvention d'équipe émergente : Médecine régénératrice et nanomédecine | Generation of Transplantable Beta-Cells from Human ES Cells | Diabetes; High-Content Imaging; Microrna; Stem Cells; Transcription Factors; Transplant |
| Kieffer, Timothy J | University of British Columbia | Subvention de fonctionnement | Effects of early overnutrition on beta-cell function | Beta-Cell; Diabetes; Leptin; Nutrition; Obesity; Postnatal Development |
| Kieffer, Timothy J | University of British Columbia | Subvention de fonctionnement | Leptin Regulation of Glucose Homeostasis | Diabetes; Glucose; Insulin; Islet; Leptin; Transgenic |
| Kienesberger, Petra C | Dalhousie University (Nova Scotia) | Subvention Projet | Autotaxin-lysophosphatidic acid signaling in obesity-related heart disease | Cardiomyocyte; Cardiomyopathy; Cell Signaling; Diabetes; Energy Metabolism; Heart Disease; Insulin; Lipids; Mitochondria; Obesity |
| Kimmins, Sarah | McGill University/Université McGill | Subvention de fonctionnement | Obesity and nutritional programming of the paternal sperm epigenome: effects on offspring development and health | Developmental Origins of Adult Disease; Dietary Folate; Environmental Programming; Epigenomics; Histones; Paternal Disease Transmission; Paternal Obesity; Reproduction; Spermatogenesis; Transgenerational Inheritance |
| King-Jones, Kirst | University of Alberta | Subvention de fonctionnement | Analysis of regulatory networks controlling cholesterol and lipid metabolism in Drosophila | Cholesterol And Lipid Metabolism; Gene Expression Profiling; Genome Wide Dna-Binding (Chip); Mutant Analysis; Nuclear Receptor; Target Gene Discovery |
| Klein, Doug | University of Alberta | Sub fonct -AP :Fonds de démarrage de INMD (Fin trans pour cliniciens & nou cher) | An evaluation of the CHANGE lifestyle intervention in primary care: a multicenter cluster randomized trial | Effectiveness; Exercise; Family Medicine; Lifestyle Intervention; Metabolic Syndrome; Nutrition; Primary Care; Randomized Control Trial |
| Klein, Doug | University of Alberta | Subv. de fonct -AP : Inst. de la Nutrition, métabolisme, diabète -fin transit. | An evaluation of the CHANGE lifestyle intervention in primary care: a multicenter cluster randomized trial | Effectiveness; Exercise; Family Medicine; Lifestyle Intervention; Metabolic Syndrome; Nutrition; Primary Care; Randomized Control Trial |
| Klip, Amira | Hospital for Sick Children (Toronto) University of Toronto |
Subvention Fondation | Cell biology and physiology of muscle insulin delivery, insulin action and insulin resistance leading to diabetes | Cell-Cell Communication; Glucose Transporters; Insulin Action And Signalling; Insulin Transcytosis; Lipotoxicity; Macrophage Activation; Microvascular Endothelium; Muscle Insulin Resistance; Obesity-Induced Inflammation; Vesicle Traffic |
| Klip, Amira | Hospital for Sick Children (Toronto) University of Toronto |
Subvention de fonctionnement | Regulation of muscle glucose transporters by Rac and Rabs during insulin action and lipotoxicity | Actin Remodelling; Glucose Transporters; Insulin Action And Signalling; Intracellular Compartments; Muscle Cells; Vesicle Traffic |
| Klip, Amira | Hospital for Sick Children (Toronto) University of Toronto |
Subvention de fonctionnement | Macrophage lipotoxic inflammation: Its mechanism, impact on insulin delivery and interplay with muscle | Cell-Cell Communication; Insulin Transcytosis; Lipotoxicity; Macrophage Activation; Microvascular Endothelium; Muscle Insulin Resistance; Obesity-Induced Inflammation; Vesicular Traffic |
| Knauper, Barbel | McGill University/Université McGill | Subvention Projet | Increasing the long-term effectiveness of behavioral weight loss programs for emotional eaters through the habitual use of acceptance-based strategies | Acceptance And Commitment Therapy; Behavioral Weight Loss Program; Emotion Regulation Skills; Emotional Eating; Habit Formation; If-Then Planning; Implementation Intentions; Lifestyle Modification Programs; Overweight And Obesity; Randomized Controlled Trial |
| Knauper, Barbel | McGill University/Université McGill | Subvention Projet | Increasing the effectiveness of weight loss programs for emotional eaters: Training emotional eaters to use acceptance-based techniques for weight loss and maintenance | Acceptance And Commitment Therapy; Behavioural Weight Loss Programs; Emotion Regulation Skills; Emotional Eating; Habit Formation; If-Then Planning; Lifestyle Modification Program; Overweight And Obesity; Physical Activity; Randomized Controlled Trial |
| Knauper, Barbel | McGill University/Université McGill | Subvention de fonctionnement | Increasing the Effectiveness of the Diabetes Prevention Program Through If-then Plans and Mental Practice: A Parallel Randomized Trial | Diabetes Prevention; Habit Formation; Implementation Intentions; Lifestyle Modification Program; Mental Practice; Physical Activity; Program Effectiveness; Weight Loss |
| Kokoeva, Maia | Research Institute of the McGill University Health Centre/Institut de recherche du Centre universitaire de santé McGill McGill University/Université McGill |
Subvention de fonctionnement | Adult neurogenesis and the central control of energy homeostasis | Adult Neurogenesis; Body Weight Set Point; Central Control Of Energy Homeostasis; Diet-Induced Obesity; Electron Microscopy; High Caloric Diet; Hypothalamus; Icv Surgery; Immunohistochemistry; Mouse Model; Neural Plasticity; Neuroendocrinology; Obesity; Type 2 Diabetes |
| Kokoeva, Maia | Research Institute of the McGill University Health Centre/Institut de recherche du Centre universitaire de santé McGillMcGill University/Université McGill | Subvention Projet | Anatomy of leptin sensing | Arcuate Nucleus; Hypothalamus; Leptin Receptor; Leptin Resistance; Median Eminence; Neurobiology Of Energy Homeostasis; Neurobiology Of Obesity |
| Koromilas, Antonis E | Lady Davis Institute for Medical Research (Mtl) McGill University/Université McGill |
Subvention de fonctionnement | Functional interactions between PI3K-Akt and eIF2alpha phosphorylation pathways: Implications in cell signaling and tumor treatment. | Apoptosis; Chemotherapeutic Drugs; Eif2alpha Phosphorylation; Endoplasmic Reticulum Stress; Mrna Translation; Oxidative Stress; Pi3k-Akt Pathway; Protein Phosphorylation; Tumorigenesis; Xenograft Tumor Assays |
| Kramer, Caroline K | Sinai Health System (Toronto) University of Toronto |
Subvention Projet | Metabolic impact of intermittent fasting in early type 2 diabetes | Blood Pressure; Body Weight; Glycated Hemoglobin; Insulin Sensitivity; Intermittent Fasting; Obesity; Pancreatic Beta-Cell Function; Time Restricted Feeding; Type 2 Diabetes |
| Kramer, Caroline K | Sinai Health System (Toronto) University of Toronto |
Subvention Projet | Empagliflozin and the Preservation of Pancreatic Beta-Cell Function in Women with Recent Gestational Diabetes | Beta-Cell Function; Clinical Trial; Empagliflozin; Gestational Diabetes; Postpartum; Pre-Diabetes; Prevention; Sglt-2; Type 2 Diabetes |
| Kramer, Caroline K | Sinai Health System (Toronto) University of Toronto |
Subvention Projet | Empagliflozin and the Preservation of Pancreatic Beta-Cell Function in Women with Recent Gestational Diabetes | Beta-Cell Function; Clinical Trial; Gestational Diabetes; Post-Partum; Pre-Diabetes; Prevention; Sglt-2; Type 2 Diabetes |
| Krause, Henry M | University of Toronto | Subv fonct : prog collab CQDM/IRSC en médecine personnalisée -demande détaillée | Zebrafish HTS platforms for nuclear receptor related drug discovery and pathway elucidation | Drug Discovery; Epigenetics; Nuclear Receptor; Transcriptome; Zebrafish |
| Krepinsky, Joan | McMaster University | Subvention Projet | The Role of Cell Surface GRP78 in the Pathogenesis of Diabetic Nephropathy | Animal Studies; Cell Signaling; Diabetic Nephropathy; Extracellular Matrix; High Glucose; Mesangial Cell; Protein Interaction Analysis; Rna Analysis; Transfection; Transforming Growth Factor Beta |
| Krepinsky, Joan | McMaster University | Subvention Projet | Role of miR-299a in regulating diabetic kidney disease | Animal Studies; Cell Signaling; Diabetic Kidney Disease; Extracellular Matrix; Fibrosis; Mesangial Cell; Micro Rna; Molecular Biology Methods |
| Krepinsky, Joan | McMaster University | Subv. de fonct -AP : Inst. de la Nutrition, métabolisme, diabète -fin transit. | The Role of ADAM17 in the Pathogenesis of Diabetic Nephropathy | Animal Studies; Diabetic Nephropathy; Extracellular Matrix; Mesangial Cell; Signaling; Transfection |
| Krepinsky, Joan | McMaster University | Subvention de fonctionnement | Does follistatin protect against diabetic nephropathy? | Activin A; Animal Studies; Diabetic Nephropathy; Extracellular Matrix; Mesangial Cell; Promoter Anlysis; Rna Analysis; Signaling; Transfection; Transforming Growth Factor Beta |
| Kuk, Jennifer Linche | York University (Toronto, Ontario) | Subv de fonct- AP : Fonds de démarrage INMD (finance trans)-nouveaux chercheurs | Causes and Implications of Metabolically Healthy Obese | Cardiovascular Disease; Clinical Weight Management; Diabetes; Epidemiology; Metabolic Syndrome; Obesity; Population Health; Weight Loss |
| Kurtz, Donna L | University of British Columbia | Subv. fonctionnement: ERMO des voies de l'équité - comp 1 - diabète et obésité | Embracing A Vision for Indigenous Health: Community Access to Prevention, Self-management and Integrated Diabetes Services in the BC Interior | Community Based Participatory Research; Health Promotion; Indigenous Methodologies And Methods; Integrated Indigenous Diabetes/Obesity Services; Interdisciplianry Multi-Sector Team Development; Rural And Remote Aborigional Populations; Urban |
| Kurtz, Donna L | University of British Columbia | Subvention Projet | Building Indigenous Pathways for Diabetes and Obesity Prevention and Management with Urban and Rural Communities in BC | Cultural Safety; Diabetes And Obesity; Implementation Science; Indigenous Community Led; Traditional And Western Knowledge Service Delivery; Urban Indigenous Health |
| L'Abbe, Mary R | University of Toronto | Subvention de fonctionnement | Food EPI - Assessing the food policy environment in Canada | Chronic Disease Prevention; Food Environment; Food Policy; Obesity; Population Health; Public Sector Policies |
| L'Abbe, Mary R | University of Toronto | Subvention Projet | The IMPACT of food environment policies on the Canadian food supply, dietary intakes and health: evidence to inform policy action | Cchs Dietary Intake; Food Environment; Menu Labelling; Nutrient Databases; Nutrient Profiling; Nutrition; Nutrition And Diet Modelling; Nutrition Policy; Sodium Reduction |
| Labbe, Aurelie | McGill University/Université McGill | Subvention de fonctionnement | Redefining the phenotype in complex diseases through latent classes to model intra- and inter-family heterogeneity: application to genetic linkage and association analysis. | Gene Expression Data; Genetic Basis Of Complex Diseases; Genetic Heterogeneity; Genetic Linkage Analysis; Latent Class Analysis; Multivariate Phenotypes |
| Lacaille, Diane V | Arthritis Research Centre of Canada (British Columbia) | Subvention de fonctionnement | Assessing the care for rheumatoid arthritis at a population level | Administrative Health Data; Arthritis; Epidemiology |
| Lam, Tony K | University Health Network (Toronto) University of Toronto |
Subvention de fonctionnement | Nutrient sensing in the Gut | Diabetes/Obesity; Food Intake; Glucose Metabolism; Gut Nutrient Sensing; Gut/Brain/Liver Axis; Pancreatic Clamp / Intestinal Administration In Vivo |
| Lam, Tony K | University Health Network (Toronto) University of Toronto |
Subvention Fondation | Metabolic Impact of Nutrient Sensing-dependent Neuronal Mechanisms in the Gut and the Brain | Bariatric Surgery / Metformin; Diabetes / Obesity; Duodenum / Jejunum / Ileum; Glucose / Lipid / Energy Homeostasis; Glucose Clamp / Ivgtt / Vldl-Tg / Energy Expenditure; Gut Microbiota; Gut-Brain-Liver-Brown Fat Axes; Hypothalamus / Dorsal Vagal Complex; Nutrient Sensing; Opto/Chemo-Genetic Approaches |
| Lam, Tony K | University Health Network (Toronto) University of Toronto |
Subvention de fonctionnement | CNS nutrient sensing and the regulation of lipid, glucose and energy homeostasis | Brain/Liver; Diabetes; Dorsal Vagal Complex; Food Intake; Glucose And Lipid Metabolism; High-Fat Feeding; Hypothalamus; Nutrient Sensing; Obesity; Pancreatic Insulin/Glucose Clamp |
| Laplante, Mathieu | Université Laval | Subvention Projet | Molecular mechanisms of adipose tissue development | Adipocyte; Adipogenesis; Adipose Tissue Development; Obesity |
| Laplante, Mathieu | Université Laval | Subvention Projet | Defining the role of DEPTOR in the regulation of brown adipose tissue development/function and evaluation of its impact on systemic metabolism | Adipogenesis; Brown Adipose Tissue; Cell Signaling; Lipid Metabolism; Obesity |
| Laplante, Mathieu | Institut universitaire de cardiologie et de pneumologie de Québec - ULaval Université Laval |
Subvention de fonctionnement | Implication of DEPTOR in the regulation of glucose/lipid homeostasis | Adipogenesis; Glucocorticoids; Glucose And Lipid Homeostasis; Insulin Resistance; Insulin Signaling; Liver Metabolism; Metabolic Diseases; Mtor Signaling; Obesity; Transgenic Mouse Models |
| Larose, Louise | Research Institute of the McGill University Health Centre/Institut de recherche du Centre universitaire de santé McGill McGill University/Université McGill |
Subvention Projet | Deciphering the role of the interaction of Nck1 and PERK in regulating pancreatic beta cell function and survival | Adaptor Protein Nck; Diabetes; Islet Transplantation; Pancreatic Beta Cells; Pancreatic Islets; Protein Kinase Perk; Unfolded Protein Response |
| Larose, Louise | McGill University/Université McGill | Subvention de fonctionnement | Role of the Adaptor Protein Nck in the Pathogenesis of Insulin Resistance and Type 2 Diabetes | Adaptor Proteins; Diabetes; Endoplasmic Reticulum Stress; Glucose And Lipid Metabolism And Homeostasis; Hepatic Gluconeogenesis; Insulin Signaling And Resistance; Nck Knock Out Mice; Obesity; Primary Hepatocytes; Unfolded Protein Response |
| Lautt, W. Wayne | University of Manitoba | IRSC/ Programme de partenariats régionaux/Subvention de fonctionnement | Mechanism of loss of vasodilation response to insulin in type 2 diabetes | Diabetes; Vascular Dysfunction |
| Lavoie, Josée G | University of Northern British Columbia | Subvention de fonctionnement | Towards closing the gap: using evidence to identify the need for investments in primary health care services on BC First Nation reserves | Access; Ambulatory Care Sensitive Conditions; Equity; First Nations; Gee Modeling; Primary Health Care |
| Law, Michael R | University of British Columbia | Subvention de fonctionnement | For Whom the Bill Tolls: Private Drug Insurance in Canada | Access To Care; Drug Use And Costs; Employer-Sponsored Health Benefits; Health Care Expenditure; Health Insurance; Pharmaceutical Policy; Policy Evaluation; Retiree Benefits |
| Lear, Scott A | St. Paul's Hospital, Vancouver University of British Columbia |
Subvention de fonctionnement | Utility of a culturally relevant or a standard exercise program to reduce visceral adipose tissue and cardiovascular disease risk in abdominally obese South Asian women | Cardiovascular Disease Risk Factors; Exercise; Obesity; Post-Menopausal Women; South Asians; Visceral Adipose Tissue |
| Lee, Ping I | University of Toronto | Subvention de fonctionnement | Novel Nitric Oxide Delivery System for Wound Healing | Critical Design Parameters Affecting No Delivery Properties; Enhanced Wound Healing In A Diabetic Animal Model; Mechanisms Of Nitric Oxide Release From The Present System; New Supramacromolecular Complexes For Extended Release Of No; Optimization Of Nitric Oxide Loading And Release; Study Of Various Physical Forms Of The Present Complexes |
| Lega, Iliana C | Women's College Research Institute (Toronto, Ontario) | Subvention Projet | The prevalence and impact of intensive diabetes treatment in older adults | Diabetes; Management; Older Adults; Overtreatment; Population-Based |
| Lehner, Richard | University of Alberta | Subvention de fonctionnement | Role of Es-x in lipid metabolism | Atherosclerosis; Fatty Liver; Genetic Engineering; Lipase; Lipoprotein Secretion; Obesity; Type 2 Diabetes |
| Lehner, Richard | University of Alberta | Subvention de fonctionnement | Molecular characterization of esterase Es-x | Atherosclerosis; Genetic Engineering; Lipolysis; Nafld; Type 2 Diabetes; Vldl Secretion |
| Lehner, Richard | University of Alberta | Subvention Projet | Metabolic role of arylacetamide deacetylase (AADAC) | Cholesterol; Flutamide Metabolism; Gene Expression; Knockout Mice; Lipase; Lipid Metabolism; Lipidomics; Lipoproteins; Liver And Intestine; Triglycerides |
| Lehner, Richard | University of Alberta | Subvention Projet | Role of a lipid hydrolase TGH in hepatic fat storage and lipoprotein secretion | Fatty Liver Disease; Insulin Resistance; Intestine; Knockout Mice; Lipase; Lipid Droplets; Lipid Metabolism; Lipoproteins; Liver; Obesity |
| Lehner, Richard | University of Alberta | Subvention de fonctionnement | Role of triacylglycerol hydrolase in lipid metabolism | Atherosclerosis; Lipolysis; Lipoproteins; Nafld; Type 2 Diabetes |
| Lemieux, Joanne M | University of Alberta | Subvention de fonctionnement | Insights into the molecular mechanism of rhomboid intramembrane peptidases | Enzymology; Intramembrane Peptidase; Membrane Protein Biochemistry; Saxs; X-Ray Crystallography |
| Leroux, Michel R | Simon Fraser University (Burnaby, B.C.) | Subvention de fonctionnement | Dissecting the molecular and cellular links between cilia, cGMP signaling, physiology and disease | Bardet-Biedl Syndrome; Cgmp Signaling; Cilia; Disease; Satiety/Obesity; Sensory Perception |
| Lévesque, Lucie | Queen's University (Kingston, Ontario) | Subv de fonctionnement : rech interventionnelle en santé des populations | Dissemination of 'Pausa Activa', a strategy to enhance physical activity promotion in health care settings in Mexico: Investigating program implementation and impact | Physical Activity Promotion; Physician Training; Primary Health Care |
| Levine, Joel D | University of Toronto | Subvention de fonctionnement | The neurogenetic basis of group dynamics in Drosophila | Behavioural Genetics |
| Levings, Megan K | BC Children's Hospital Research Institute University of British Columbia |
Subvention de fonctionnement | Molecular and cellular biology of T regulatory cells | T Cell Signalling; T Regulatory Cells; Tolerance |
| Levitan, Robert D | Centre for Addiction and Mental Health (Toronto)/Centre de toxicomanie et de santé mentale University of Toronto |
Subvention de fonctionnement | An Early Developmental Model of Overeating, Obesity and Executive Dysfunction | Attention Deficit; Dopamine; Executive Function; Fetal Adversity; Food Reward; Genes; Impulsivity; Obesity |
| Lewis, Gary F | University Health Network (Toronto) University of Toronto |
Subvention de fonctionnement | Regulation of intestinal and hepatic lipoprotein particle secretion in humans | Fat; Glp-1; Glp-2; Human; Intestine; Lipoprotein Metabolism; Resveratrol; Stable Isotopes |
| Lewis, Gary F | University of Toronto | Subvention Projet | Novel Aspects of the regulation of intestinal lipoprotein particle secretion in humans | Apolipoprotein; Diabetes; Insulin Resistance; Intestine; Lipoprotein; Liver |
| Libman, Eva | CIUSSS de Centre-Ouest-de-l'Ile-de-Montréal-Jewish General/CIUSSS de Centre-Ouest-de-l'Ile-de-Montréal-Hôpital juif McGill University/Université McGill |
Subvention de fonctionnement | Daytime functioning and sleep disorders in older adults: Predicting sleep apnea in a prospective primary care study | Aging; Case Identification; Health Risks; Polysomnography; Primary Care; Sleep Apnea; Symptoms |
| Light, Peter E | University of Alberta | Subvention Projet | Novel protective roles for ATP-sensitive potassium channels in the heart | Electrophysiology; Heart; Heart Failure; Ischemic Heart Disease; Katp Channels; Metabolism; Sulfonylureas |
| Light, Peter E | University of Alberta | Subvention de fonctionnement | Novel protective roles for ATP-sensitive potassium channels in the heart | Amp Activated Kinase; Atp-Sensitive Potassium Channel; Cardioprotection; Electrophysiology; Ion Channels; Ionic Homeostasis; Ischemia Reperfusion Injury; Patch-Clamp |
| Light, Peter E | University of Alberta | Subvention Projet | Characterization of a novel light-sensitve signalling pathway in subcutaneous human adipocytes | Adipocytes; Adipokines; Diabetes; Melanopsin; Obesity; Trpc Channels |
| Light, Peter E | University of Alberta | Subvention de fonctionnement | ATP-sensitive potassium channels: common variants, pharmacogenomics and type 2 diabetes risk | Atp-Sensitive Potassium Channels; Beta-Cell; Common Genetic Variants; Metabolism; Patch-Clamp; Type 2 Diabetes |
| Lim, Gareth E | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention Projet | Targeting molecular scaffolds for the treatment of obesity and metabolic disease | 14-3-3; Adipocyte; Adipogenesis; Differentiation; Metabolism; Obesity; Progenitor; Proteomics; Scaffold |
| Lima, Viviane D | University of British Columbia | Subvention Projet | The Health and Economic Forecasting Micro-Simulation Model: A tool to evaluate future health policies and programmatic interventions targeting the aging population living with HIV in British Columbia | Aging; Comorbidities; Forecasting; Healthcare Expenditure; Healthcare Utilization; Hiv; Intervention; Micro-Simulation Model; Mortality; Quality Of Life |
| Lipscombe, Lorraine | Women's College Hospital (Toronto) University of Toronto |
Subvention Projet | Avoiding diabetes after pregnancy trial in moms (ADAPT-M) | Diabetes Education; Diabetes Prevention; Gestational Diabetes; Lifestyle Intervention |
| Lipscombe, Lorraine | Women's College Hospital (Toronto) University of Toronto |
Subvention de fonctionnement | The Influence of Diabetes on Cancer Screening and Prognosis | Cancer; Cancer Screening; Diabetes; Health Services |
| Lisonkova, Sarka | University of British Columbia | Operating Grant: NI grants in MRC&Y Health – Nutrition, Metabolism and Diabetes | Improving maternal and perinatal outcomes in high risk mothers | Maternal Health; Perinatal Epidemiology |
| Lix, Lisa M | University of Saskatchewan | Subvention de fonctionnement | Completeness of Physician Billing Claims Administrative Health Databases in Canada | Administrative Health Databases; Chronic Disease; Completeness; Data Quality; Pan-Canadian Study; Prevalence |
| Loewen, Christopher | University of British Columbia | Subvention de fonctionnement | Endoplasmic reticulum membrane contact sites: role in ER polarization, lipid metabolism and protein trafficking | Amyotrophic Lateral Sclerosis (Als); Endoplasmic Reticulum; Lipid Metabolism; Lipid Transfer Protein; Membrane Contact Sites; Nonvesicular Traffic |
| Lopaschuk, Gary D | University of Alberta | Subvention Projet | Branched Chain Amino Acid Contribution to Cardiac Insulin Resistance in Heart Failure | Branched Chain Amino Acids; Fatty Acid Oxidation; Glucose Oxidation; Heart Failure; Insulin Resistance; Mtor; Obesity |
| Lopaschuk, Gary D | University of Alberta | Subvention Fondation | Optimizing cardiac energy metabolism to treat heart disease | Energy Metabolism; Fatty Acid Oxidation; Glucose Oxidation; Heart; Heart Failure; Ischemic Heart Disease; Ketone Oxidation; Mitochondria |
| Lopaschuk, Gary D | University of Alberta | Subvention Projet | The metabolic basis if heart failure in diabetes and obesity | Acetylation; Diabetes; Fatty Acid Oxidation; Glucose Oxidation; Heart Failure; Hypertrophy; Insulin Resistance; Mitochondria; Mtor; Obesity |
| Luciani, Dan S | BC Children's Hospital Research Institute University of British Columbia |
Subvention de fonctionnement | Control of beta-cell mitochondrial physiology and adaptation by core anti-apoptosis proteins | Apoptosis; Autophagy; Diabetes; High Fat Diet; In Vivo Glucose Homeostasis; Islet Biology; Knockout Mouse Models; Live Cell Microscopy; Metabolic Stress; Mitochondrial Physiology |
| Luciani, Dan S | BC Children's Hospital Research Institute University of British Columbia |
Subvention de fonctionnement | Control of beta-cell mitochondrial physiology by core anti-apoptosis proteins | Apoptosis; Diabetes; In Vivo Glucose Homeostasis; Islet Biology; Knockout Mouse Models; Live Cell Microscopy; Metabolic Stress; Mitochondrial Physiology |
| Luheshi, Giamal N | CIUSSS de l'Ouest-de-l'Ile-de-Montréal-Douglas Hospital/CIUSSS de l'Ouest-de-l'Ile-de-Montréal-Hôpital Douglas McGill University/Université McGill |
Subvention de fonctionnement | The effects of obesity on the immune response to infection: mechanisms and sites of action | Adipokines; Fever; Immune Response; Immunoassays; Infection/Inflammation; Obesity |
| Luo, Zhong-Cheng | Université de Montréal | Subvention de fonctionnement | Quebec Administrative health databases linkage-based study on First Nations and Inuit birth and infant outcomes | Aboriginal Maternal And Infant Health; Administrative Health Database Linkage; Gestational Diabetes; Gestational Hypertension; Infant Mortality; Macrosomia; Perinatal Epidemiology; Perinatal Mortality; Preterm Birth |
| Lye, Stephen J | Lunenfeld-Tanenbaum Research Institute (Toronto) University of Toronto |
Subvention de fonctionnement | Gene-environment interactions underlying the developmental origins of health and disease | Developmental Origins Of Health And Disease; Gene-Environment Interactions; Hypothalamic-Pituitary-Adrenal Axis; Metabolic Syndrome; Pregnancy Complications |
| Lye, Stephen J | Lunenfeld-Tanenbaum Research Institute (Toronto) University of Toronto |
Subvention de fonctionnement | A Murine Model to Investigate the Mechanisms Underlying DOHaD | Developmental Health; Developmental Origins Of Health And Disease; Fetal Growth And Development; Metabolic Syndrome; Pregnancy |
| Lynn, Francis C | University of British Columbia | Subvention de fonctionnement | Post-transcriptional control of Sox9 during endocrine pancreas development: role of microRNAs | Development; Diabetes; Human Embryonic Stem Cells; Microrna; Sox9; Transcription Factor |
| Lynn, Francis C | BC Children's Hospital Research Institute University of British Columbia |
Subvention Projet | Cell cycle regulation of human pancreatic endocrine cell development | Cell Cycle; Diabetes; Differentiation; Endocrine Cells; Genome Editing; Human Embryonic Stem Cells; Insulin; Neurog3; Pancreas; Transcription Factors |
| Lynn, Francis C | University of British Columbia | Subvention de fonctionnement | Npas4 Regulation of Glucose Homeostasis | Bhlh-Pas; Endoplasmic Reticulum Stress; Gene Transcription; Glucolipodysfunction; Impaired Glucose Tolerance; Insulin Gene Expression; Insulin Secretion; Obesity; Type 2 Diabetes; ß-Cell Biology |
| Lytton, Jonathan | University of Calgary | Subvention Projet | Obesity, Diabetes & Eating Disorders: The role of Calcium Signaling and the Calcium Transporter, NCKX4 | Calcium Signalling; Diabetes; Membrane Transport; Molecular Biology; Obesity; Sodium-Calcium Exchange |
| MacDonald, Patrick E | University of Alberta | Subvention Fondation | The pancreatic islet in human health and diabetes | Biobank; Cell Physiology; Diabetes; Exocytosis; Insulin; Ion Channels; Islets Of Langerhans; Metabolism; Patch-Clamp; Secretion |
| MacDonald, Patrick E | University of Alberta | Subvention de fonctionnement | Novel roles for K+ channels in islet function and the pathophysiology of diabetes | Calcium; Cellular Imaging; Diabetes; Exocytosis; Human Cells; Insulin; Ion Channels; Islets Of Langerhans; Patch-Clamp; Secretion |
| MacDonald, Patrick E | University of Alberta | Subvention de fonctionnement | Regulation of pancreatic beta-cell exocytosis and insulin secretion by SUMOylation | Excitosome; Exocytosis; Insulin; Ion Channels; Senp; Snare Proteins; Sumo; Ubc9 |
| MacDonald, Patrick E | University of Alberta | Subvention de fonctionnement | Regulation of pancreatic beta-cell exocytosis and insulin secretion by SUMOylation | Excitosome; Exocytosis; Insulin; Ion Channels; Snare Proteins; Sumo |
| Macleod, Kathleen M | University of British Columbia | Subvention de fonctionnement | Abnormalities of signaling pathways in diabetic cardiomyopathy: Implications for new treatment | Biochemical Analysis; Diabetic Cardiomyopathy; Heart Function; Mitochondria; Protein Kinase C; Rho Kinase |
| Maguire, Jonathon L | St. Michael's Hospital (Toronto) University of Toronto |
Subv. de fonctionnement: Subv. pluriannuelle : essais clin. novateurs de la SRAP | CoMFORT (Cow's Milk Fat Obesity pRevention Trial) | Epidemiology; Nutrition; Obesity; Pediatrics; Vitamin D |
| Mahmud, Farid | Hospital for Sick Children (Toronto) University of Toronto |
Subvention de fonctionnement: SRAP & JDRF - Subv. pluriannuelle ECN | Adolescent Type 1 diabetes Treatment with EMPaglifozin for hyperglycemia & hyperfilTration Trial, "ATTEMPT" Trial | Adolescence; Cardiovascular Disease; Diabetes Mellitus; Diabetic Nephropathy; Hyperfiltration; Metabolic Control; Patient-Oriented Research; Randomized Controlled Trial |
| Mahon, Jeffrey L | University of Western Ontario | Essais contrôlés randomisés | Trial to Reduce IDDM in the Genetically at Risk (TRIGR) | Avoidance Of Cow¿S Milk Protein In Diet; Complex And Family History Risk; Intervention To Prevent Diabetes Within 6-8 Mths Age; Major Histocompatibility; Newborns At High Risk For Diabetes Mellitus; Randomized Double-Blinded Control Trial |
| Mailhot, Geneviève | Centre hospitalier universitaire Sainte-Justine
Université de Montréal |
Subvention de fonctionnement | Homéostasie intestinale de la vitamine D chez la fibrose kystique : Rôle du CFTR | Cftr; Culture Cellulaire; Fibrose Kystique; Malabsorption; Physiologie Intestinale; Vitamine D |
| Manns, Braden J | University of Calgary | Subvention Fondation | Informing health care policy makers on health care financing and sustainability | Cost Sharing; Costing Studies; Economic Evaluation; Health Policy; Knowledge Translation; Medication Co-Payment; Pharmaceutical Policy; Randomized Trials |
| Manns, Braden J | University of Calgary | Partenariats pour l'amélioration du système de santé (PASS) | The Impact of Primary Care Networks on the Care and Outcome of Patients with Diabetes | Ambulatory Care Sensitive Conditions; Chronic Disease Management; Diabetes; Health Services Research; Outcomes; Primary Care Network |
| Manson, Heather | Ontario Agency for Health Protection and Promotion (Toronto, Ontario)/L'Agence ontarienne de protection et de promotion de la santé University of Toronto |
Subv de fonctionnement : rech interventionnelle en santé des populations - Pathways | Cultivating community partnerships to assess the impact of a population health intervention targeting Aboriginal children and youth for promoting healthy weights in Ontario | Aboriginal Peoples' Health; Indigenous Ways Of Knowing And Doing; Program Evaluation; Qualitative Methods |
| Manuel, Douglas G | Ottawa Hospital Research Institute/Institut de recherche de l'Hôpital d'Ottawa University of Ottawa/Université d'Ottawa |
Subvention Projet | Measuring compression and expansion of morbidity from chronic diseases using a multivariable predictive approach | Morbidity; Mortality; Population Health |
| Marette, André | Université Laval | Subvention de fonctionnement | Role of iNOS in the pathogenesis of insulin resistance | Adiponectin; Adipose Tissue; Ampk; Enos; Glucose Metabolism; Inos |
| Marette, André | Université Laval | Subvention de fonctionnement | Metabolic functions of the PTPase SHP-1 in insulin target tissues | Adipose Tissue; Glucose Metabolism; Insulin Resistance; Insulin Signaling; Lipid Metabolism; Liver; Obesity; Protein Tyrosine Phosphatase; Skeletal Muscle; Steatosis |
| Marette, André | Université Laval | Subvention de fonctionnement | Role of the mTOR/S6K1 and RSK pathways in the pathogenesis of insulin resistance | Adipose Tissue; Animal Models; Cell Culture; Diabetes; Glucose Transport; Insulin Resistance; Liver; Muscle; Nutrient Sensing |
| Marette, André | Université Laval | Subvention de fonctionnement: Le sucre et la santé - Sucre et santé | Effect of free sugar replacement with non-nutritive sweeteners on metabolic health of high sugar sweetened beverages consumers: role of the gut microbiome | Diabetes; Gut Microbiota; Human Subjects; Metabolic Syndrome; Metabolism; Microbiome; Non-Nutritive Sweeteners; Nutrition; Sugar Sweetened Beverages; Sugars |
| Marette, André | Université Laval | Subvention de fonctionnement | Metabolic functions of the PTPase SHP-1 in insulin target tissues | Adipose Tissue; Glucose Metabolism; Insulin Resistance; Insulin Signaling; Lipid Metabolism; Liver; Obesity; Protein Tyrosine Phosphatase; Skeletal Muscle; Steatosis |
| Marette, André | Université Laval | Sub fonct : sub rech program alimen & santé -Rech biomédical fondamentale | Translational approach to establish the cardiometabolic health effects and mechanisms of action of fish nutrients: from animal models to obese insulin-resistant subjects | Animal Models; Cardiovascular Disease; Fish Nutrients; Human Subjects; Insulin Resistance; Metabolomics; Nutrigenomics; Obesity; Type 2 Diabetes; Vitamin D |
| Marette, André | Université Laval | Subvention de fonctionnement | Role of the mTOR/S6K1 pathway in the pathogenesis of insulin resistance | Adipose Tissue; Animal Models; Cell Culture; Diabetes; Glucose Transport; Insulin Resistance; Liver; Muscle; Nutrient Sensing |
| Marette, André | Université Laval | Subvention de fonctionnement | Role of iNOS in the pathogenesis of insulin resistance | Adiponectin; Adipose Tissue; Ampk; Enos; Glucose Metabolism; Inos |
| Marette, André | Université Laval | Subvention Fondation | Pathogenesis and treatment of obesity-linked inflammation, insulin resistance and cardiometabolic complications | Adipose Tissue; Cardiovascular Disease; Diabetes; Fatty Liver Disease; Genetic Models; High-Fat Diet; Inflammation; Liver; Obesity; Skeletal Muscle |
| Marliss, Errol B | Research Institute of the McGill University Health Centre/Institut de recherche du Centre universitaire de santé McGill McGill University/Université McGill |
Subvention de fonctionnement | Mechanisms of insulin resistance of protein metabolism in human obesity | Insulin Resistance; Mass Spectrometry; Muscle Biopsies; Obesity; Protein Synthesis And Catabolism; Stable And Radioactive Isotope Studies |
| Marzban, Lucy | University of British Columbia | Subvention de fonctionnement | Molecular mechanisms of islet amyloid mediated beta cell death | Adenoviral Transduction; Amyloid; Beta Cell; Histology; Islet Transplantation; Type 2 Diabetes |
| Marzban, Lucy | Vancouver Coastal Health Research Institute University of British Columbia |
Subvention de fonctionnement | Molecular mechanisms of islet amyloid mediated beta cell death | Adenoviral Transduction; Animal Studies; Beta Cell Apoptosis; Beta Cell Function; Cell Culture; Histology; Insulin; Islet Amyloid; Islet Transplantation; Type 2 Diabetes |
| Masse, Louise C | University of British Columbia | Subvention de fonctionnement | Household environmental framework pertaining to childhood obesity: Improving our measures of the familial environment | Childhood Obesity; Familial Environment; Item Bank; Nutrition; Physical Activity; Psychometric; Questionnaire Design; Validation |
| Mathieu, Patrick | Université Laval | Subvention de fonctionnement | The role of ectonucleotidase in the calcification of the aortic valve | Calcific Aortic Valve Disease; Calcification; Diabetes; Ectonucleotidase; Hypertension; Insulin Resistance |
| Matsubara, Joanne A | University of British Columbia | Subvention Projet | Treating advanced retinal degeneration - rebuilding multiple co-dependent retinal layers with stem cells | Combined Rpe And Photoreceptor Graft; Rebuilding Multiple Lost Retinal Layers; Regenerative Ophthalmology; Retinal Degenerative Diseases; Stem-Cell- And Device-Based Therapy |
| McBrien, Kerry | University of Calgary | Subv. de fonctionnement: Subv. pluriannuelle : essais clin. novateurs de la SRAP | ENCOMPASS: ENhancing COMmunity health through Patient navigation, Advocacy and Social Support | Chronic Disease; Cluster-Randomized Controlled Trial; Community Health Workers; Implementation Science; Patient Navigation; Primary Health Care |
| McDonald, Sarah D | McMaster University | Subvention de fonctionnement : santé maternelle et infantile | Understanding why some women do not breastfeed | Breastfeeding; Hierarchical Modelling; Niday Database; Observational Studies; Predictor Variables |
| McDonald, Sarah D | McMaster University | Subvention de fonctionnement | Understanding Excessive Pregnancy Weight Gain: A Consideration of Psychological and other Determinants as a Prelude to Developing Interventions | Excess Pregnancy Weight Gain; Knowledge Determinants; Lifestyle Determinants; Obesity; Physical Determinants; Psychological Constructs; Qualitative Research; Weight Trajectories |
| McDonald, Sarah D | McMaster University | Subvention sur la synthèse des connaissances | Synthesizing the evidence on psychological determinants of pregnancy weight gain: A prerequisite to developing effective interventions | Gestational Weight Gain; Infant Weight; Maternal Health; Obesity; Psychologic Determinants; Weight Trajectories |
| McDonald, Sarah D | McMaster University | Subvention sur la synthèse des connaissances | Synthesizing the best evidence for weight gain during pregnancy in obese women: were the national guidelines excessive? | Gestational Weight Gain; Guideline Revision; Infant Health; Infant Macrosomia; Maternal Health; Obesity; Weight Trajectories |
| McFarlane, Sarah | University of Calgary | Subvention Projet | Identification and testing of novel inhibitors of pathological eye angiogenesis | Angiogenesis; Cell Guidance; Development; Eye; Model Organism; Neuron; Photoreceptor; Retinopathy; Semaphorins; Zebrafish |
| Mcgavock, Jonathan M | University of Manitoba | Subvention de fonctionnement | The Physical activity for OverWEight youth at Risk for type 2 diabetes (POWER) Trial | Childhood; Exercise; Insulin Sensitivity; Magnetic Resonance Spectroscopy; Obesity; Type 2 Diabetes |
| Mcgavock, Jonathan M | University of Manitoba | Subvention Projet | If you build it, will they come?...and live longer? | Built Environment; Cardiovascular Disease; Natural Experiment; Physical Activity; Population Health Intervention |
| Mcgavock, Jonathan M | University of Manitoba | Subvention de fonctionnement - AP: Programme de partenariats régionaux: Manitoba | Aboriginal Youth Mentorship Program for increasing Physical Activity in Youth in Northern Aboriginal Communities | Aboriginal; Childhood Obesity; Peer-Mentoring; Physical Activity; Self Efficacy; Type 2 Diabetes |
| Mcgavock, Jonathan M | University of Manitoba | Subvention de fonctionnement | Aboriginal Youth Mentor Program | Community-Based Participatory Action; Mentorship; Obesity; Physical Activity; Type 2 Diabetes |
| Mcgavock, Jonathan M | University of Manitoba | Équipe : Équipes de recherche (Voies de l'équité) - composante 3 | Deepening the roots of living in a good way for Indigenous Children. The Indigenous Youth Mentorship Program | Child Well-Being; Implementation Science; Indigenous Health; Indigenous Knowledge; Peer-Led Interventions; Resilience; Type 2 Diabetes Prevention |
| McGrath, Jennifer J | Concordia University (Montreal, Quebec)/Université Concordia | Subvention de fonctionnement | Sleep and Obesity in Children and Adolescents: Identifying Pathogenic Pathways | Adolescents; Ambulatory Monitoring; Child Health; Children; Metabolic Syndrome; Obesity; Psychophysiology; School; Sleep; Stress Response System |
| McGrath, Jennifer J | Concordia University (Montreal, Quebec)/Université Concordia | Nouveau chercheur des IRSC | Sleep and Obesity in Children and Adolescents: Identifying Pathogenic Pathways | Childhood Obesity |
| Mcguire, John J | Memorial University of Newfoundland | Subv de fonct. - AP: Programme de partenariats régionaux-Terre Neuve et Labrador | Acute and chronic PAR2 activation in endothelial dysfunction | Blood Pressure Telemetry; Calcium Imaging; Cell-Cell Communication; Diabetes Complications; Endothelial Cells Dysfunction; Hypertension; In Vivo Pharmacology; Inflammation; Isolated Blood Vessels; Protease-Activated Receptors |
| Mcinnes, Natalia | McMaster University | Subvention de fonctionnement - AP : soins bariatriques (fin transitoire) | Evaluation of the early effects of Roux-en-Y gastric bypass surgery combined with perioperative caloric restriction on hepatic fat in obese patients with type 2 diabetes as compared to caloric restriction alone | Bariatric Surgery; Fatty Liver; Randomized Controlled Trial; Type 2 Diabetes |
| McMaster, Christopher R | Dalhousie University (Nova Scotia) | Subv de fonct - AP : Menaces existantes et émergentes et maladies chroniques | A Novel Antibiotic Class to Treat Diabetic Ulcer Infections | Antibiotics; Diabetic Ulcer Infection; Drug Development; Pharmacology |
| McMaster, Christopher R | Dalhousie University (Nova Scotia) | Subvention de fonctionnement | A Novel Antibiotic Class to Treat Diabetic Ulcer Infections | Antibiotics; Diabetic Ulcer Infection; Drug Development; Pharmacology |
| McMurtry, Michael S | University of Alberta | Subvention de fonctionnement | Vascular Metabolism and Angiogenesis | Angiogenesis; Arteriogenesis; Endothelium; Hindlimb Ischemia; Metabolism; Mitochondria |
| Mcpherson, Amy | Holland Bloorview Kids Rehabilitation Hospital (Toronto) University of Toronto |
Subvention sur la synthèse des connaissances | Talking with children and families about weight-related issues: A scoping review of best practices | Communication; Scoping Review; Weight Discussions; Weight Management |
| McPherson, Ruth | University of Ottawa Heart Institute/Institut de cardiologie de l'Université d'Ottawa University of Ottawa/Université d'Ottawa |
Subvention de fonctionnement | Metabolic and genetic determinants of obesity and obesity-related phenotypes | Adipose Tissue; Candidate Genes; Gene Expression; Genetics; Genome Wide Association Studies; Insulin Sensitivity; Lipoproteins; Obesity; Oxidative Phosphorylation |
| Melichar, Heather | CIUSSS Est-de-l'Ile-de- Montréal-Maisonneuve Rosemont Université de Montréal |
Subvention de fonctionnement | Determining cause and effect: dynamic T cell receptor signaling during thymic selection | Negative Selection; Organotypic Culture; Positive Selection; Regulatory T Cell; T Cell Receptor Signaling; Thymus; Tissue Restricted Antigens; Two-Photon Microscopy |
| Merali, Zulfiquar | University of Ottawa Institute of Mental Health Research/Institut de recherche en santé mentale de l'Université d'Ottawa University of Ottawa/Université d'Ottawa |
Subvention de fonctionnement | Stress-reducing effects of palatable foods: brain mechanisms and implications for obesity | Anxiety; Bombesin-Like Peptides; Corticotropin-Releasing Factor; Ghrelin; Ingestive Behavior; Microdialysis; Neuropeptides; Obesity; Stress |
| Michaud, Véronique | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention de fonctionnement | Effects of Type 2 Diabetes (T2D) on drug disposition and CYP450 activities; a special look at extra-hepatic metabolism | Cytochromes P450; Drug Analysis; Drug Metabolism; Lc-Ms/Ms; Molecular Biology; Pharmacogenetics; Pharmacokinetics; Phenotype; Type 2 Diabetes |
| Mills, Susan L | University of British Columbia | Subvention sur la synthèse des connaissances | Realist Synthesis of Self-Management Interventions for Disadvantaged Populations with Chronic Conditions | Chronic Conditions; Disadvantaged Populations; Primary Care; Realist Synthesis; Self-Management Interventions |
| Mitchell, Grant A | Centre hospitalier universitaire Sainte-Justine Université de Montréal |
Subvention de fonctionnement | Lipolysis: Biochemical Genetics, Physiology and Molecular Circuitry | Biochemical Genetics; Lipases; Lipidology; Mouse Models; Obesity |
| Mitchell, Lesley G | University of Alberta | Subvention de fonctionnement | Acquired abnormalities in the hemostatic system in obese children prone to Type 2 diabetes: Mechanisms and interventions for risk of cardiovascular disease | Animal Models; Blood Proteins; Cardiovascular Disease; Cell Signalling; Clinical Studies; Coagulation/Fibrinolytic Capacity; Gene Expression; Obesity; Pediatrics; Type 2 Diabetes |
| Mitton, Craig R | University of British Columbia | Subv de fonctionnement : rech interventionnelle en santé des populations | Evaluation of Vancouver Coastal Health's Second Generation Strategy for the Downtown Eastside (DTES): a population health intervention study | Health Policy Analysis; Population Health Intervention; Priority Setting And Resource Allocation; Program Evaluation |
| Mizuno, Tooru M | University of Manitoba | Subvention de fonctionnement - AP: Programme de partenariats régionaux: Manitoba | Regulation of lipid metabolism by xenin | Biological Rhythm; Gut Hormone; Hypothalamus; Leptin; Lipid Metabolism; Lipolysis; Obesity; Sympathetic Nervous System |
| Mizuno, Tooru M | University of Manitoba | IRSC/ Programme de partenariats régionaux/Subvention de fonctionnement | Role of xenin in the regulation of energy balance | Central Nervous System; Food Intake; Gastrointestinal Peptide; Obesity |
| Moher, David | Ottawa Hospital Research Institute/Institut de recherche de l'Hôpital d'Ottawa University of Ottawa/Université d'Ottawa |
Subvention sur la synthèse des connaissances | Do sugar-sweetened beverages cause adverse health outcomes in adults? A systematic review | Adult; Cancer; Cardiovascular Disease; Chronic Disease; Diabetes; Metabolic Syndrome; Obesity; Sugar-Sweetened Beverage; Systematic Review |
| Moher, David | Ottawa Hospital Research Institute/Institut de recherche de l'Hôpital d'Ottawa University of Ottawa/Université d'Ottawa |
Subvention sur la synthèse des connaissances | Do sugar-sweetened beverages cause adverse health outcomes in children? A systematic review | Academic Achievement; Children; Chronic Disease; Diabetes; Dyslipidemia; Hypertension; Obesity; Pediatric; Sugar-Sweetened Beverage; Systematic Review |
| Mourtzakis, Marina | University of Waterloo (Ontario) | Subvention de fonctionnement | Evaluation of nutrition and metabolism in breast cancer patients | Body Composition; Breast Cancer; Exercise; Lipid; Metabolism; Muscle; Nutrition; Obesity |
| Muckle, Gina | Université Laval | Subvention de fonctionnement | Environmental Contaminants and Adolescent Development | Aboriginal Health; Adolescents Development And Health; Environmental Contaminants; Prenatal Exposure; Public Health |
| Mui, Alice L | Vancouver Coastal Health Research Institute University of British Columbia |
Subvention Projet | Mechanism underlying hyporesponsiveness to Interleukin-10 in Type II Diabetes | Ampk; Biomarker; Inflammation; Macrophage; Ship1 Inositol Phosphatase; Type 2 Diabetes |
| Mulvihill, Erin E | University of Ottawa Heart Institute/Institut de cardiologie de l'Université d'Ottawa University of Ottawa/Université d'Ottawa |
Subvention Projet | Glucose Lowering in T2DM: Mechanism of Action of Dipeptidyl Peptidase 4 Inhibitors | Dipeptidyl Peptidase 4; Incretin Hormones; Insulin; Islets; Metabolism; Mouse Genetics; Type 2 Diabetes Mellitus |
| Munoz, Douglas P | Queen's University (Kingston, Ontario) | Subvention de fonctionnement | Establishment of a primate model that exhibits Alzheimer's-like features to explore new preventative and therapeutic strategies | Alzheimer's Disease; Behavioural Phenotyping; Biomarkers; Executive Function; Frontal Cortex; Insulin Signalling; Memory Control; Saccadic Eye Movements |
| Murshed, Monzur | McGill University/Université McGill | Subvention de fonctionnement | Molecular mechanisms underlying the vascular calcification phenotype in matrix gla protein-deficient mice | Arteriovenous Malformation; Blood Vessels; Bone Mineralization; Ectopic Calcification; Elastin; Extracellular Matrix; Genetics; Matrix Degrading Enzymes; Matrix Gla Protein; Transgenic And Knockout Models |
| Mutch, David M | University of Guelph | Sub fonct -AP :Fonds de démarrage de INMD (Fin trans pour cliniciens & nou cher) | FADS2 modulates n-3 fatty acid regulation of adipose tissue inflammation | Adipokines; Adipose Tissue; Clinical Study; Eicosanoids; Fatty Acid Desaturase 2; Inflammation; Knock-Out Mouse Model; Microarray; N-3 Fatty Acids; Translational Research |
| Nagy, Andras | Sinai Health System (Toronto) University of Toronto |
Équipes Canada-Japon du CCREES en épigénétique des cellules souches | Directing Cellular Identity to Move Towards Progenitor Cell Therapies | Cell Based Therapy; Cell Therapy Safety; Disease Models; Duchenne Muscular Dystrophy; Epigenetics; Gene Correction; In Vitro Differentiation; Induced Pluripotent Stem Cells; Reprogramming; Rett Syndrome |
| Ng, Dominic S | St. Michael's Hospital (Toronto) University of Toronto |
Subvention de fonctionnement | The role of cholesterol in the modulation of ER stress and diabetogenesis | Diabetes Mellitus; Fatty Acids Metabolism; Gene Knockout Mice; High Density Lipoproteins; Obesity; Regulation Of Gene Expressions |
| Nuyt, Anne Monique | Centre hospitalier universitaire Sainte-Justine Université de Montréal |
Subvention de fonctionnement : santé maternelle et infantile | Devenir obstétrical des femmes nées prématurément | Complication De Grossesse; Diabète Gestationnel; Hypertension Gravidique; Programmation Développementale; Prématurité; Prééclampsie |
| Nuyt, Anne Monique | Centre hospitalier universitaire Sainte-Justine Université de Montréal |
Subvention de fonctionnement | Risk of Chronic Diseases in Young Adults Born Preterm: Relationship with Inflammation and Oxidative Stress Biomarkers | Cardio Metabolic Disease; Chronic Health Disease; Clinical Study; Developmental Programing Of Adult Diseases; Inflammation; Oxidative Stress; Prematurity |
| Nykiforuk, Candace | University of Alberta | Sub fonct : promouvoir les innovations théoriques & méthodologiques domaine rech | Assessing Community Environments for Physical Activity and Healthy Eating: Development of Innovative Mixed-Methods Approaches for Utilizing Objective and Subjective Data | Built Environment; Community Health; Discriminant Function Analysis; Health Outcomes; Mixed Methods; Participatory Workshops |
| O'Loughlin, Jennifer L | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention de fonctionnement - Analyse secondaire des bases de données | Understanding the evolving Canadian public health landscape for chronic disease prevention: Critical longitudinal analyses of Public Health Organizational Capacity Study (PHOrCaSt) data | Chronic Disease Prevention; Epidemiology; Longitudinal Analyses; National Survey; Organizational Capacity; Organizational Research; Population Health; Preventive Health Services; Transfer Practices |
| O'Reilly, Daria J | McMaster University | Subvention de fonctionnement | Development of an open source diabetes economic model | Chronic Disease Model; Decision Analytic Modelling; Diabetes; Economic Evaluation |
| Orellana, Arturo | York University (Toronto, Ontario) | Subvention Projet | Developing small molecules targeting LXRb for the treatment of glucocorticoid induced diabetes | Drug Discovery; Glucocorticoids; Lxrb; Medicinal Chemistry; Nuclear Receptors; Pharmacokinetics |
| Oudit, Gavin Y | University of Alberta | Subvention de fonctionnement | Role of ACE2 in Heart Disease: Pathophysiology, Molecular Mechanisms and Therapeutics | Diabetes Mellitus; Echocardiography; Heart Failure; Knockout Mouse Model; Signaling |
| Packer, Tanya L | Dalhousie University (Nova Scotia) | Subvention Projet | Developing a Patient-Centred, Clinically Relevant Measure of Self-management for Individuals with Multiple Chronic Conditions | Chronic Disease Self-Management; Measurement; Multi-Morbidity; Patient Reported Outcomes |
| Padwal, Raj S | University of Alberta | Subvention de fonctionnement | Outcome Assessment to Optimize Patient Selection for Bariatric Surgery (OASIS) | Access To Care; Bariatric Surgery; Diabetes; Health Economics; Health Services; Mortality; Obesity; Patient Selection; Quality Of Life; Triage |
| Palazzo, Alexander F | University of Toronto | Subvention de fonctionnement | The role of RanBP2 and sumoylation in regulating the translation of secretory mRNAs | Acute Necrotizing Encephalopathy; Cytokines; Endoplasmic Reticulum; Mrna Translation; Secretion; Sumoylation |
| Pamidi, Sushmita | Research Institute of the McGill University Health Centre/Institut de recherche du Centre universitaire de santé McGill McGill University/Université McGill |
Subvention Projet | Maternal sleep-disordered breathing during pregnancy and long-term health outcomes in children: the 3D pregnancy and birth cohort | Cardiometabolic; Child Health; Neurocognitive; Obesity; Pregnancy; Sleep Apnea |
| Pamidi, Sushmita | Research Institute of the McGill University Health Centre/Institut de recherche du Centre universitaire de santé McGill McGill University/Université McGill |
Subvention de fonctionnement | The Effect of Continuous Positive Airway Pressure (CPAP) Treatment on Glycemic Control in Gestational Diabetes: A Pilot Randomized-Controlled Trial | Continuous Positive Airway Pressure (Cpap); Gestational Diabetes; Glucose Control; Pregnancy; Sleep Apnea |
| Paradis, Hélène | Memorial University of Newfoundland | Subv de fonct. - AP: Programme de partenariats régionaux-Terre Neuve et Labrador | Tubedown signaling pathway as a therapeutic target for age-related retinopathies | Acetyltransferase; Age-Related Rethinopathies; Aging; Animal Model; Endothelium; Neovascularization; Permeability; Signaling Pathway; Transgenic; Treatment |
| Paré, Guillaume | McMaster University | Sub de fonctionnement : programme de recherche en collaboration avec l'industrie | Integration of clinical, biomarker, and genetic data for prediction of adverse outcomes in diabetes | Biomarkers; Cardiovascular Disease; Diabetes; Genetics; Kidney Disease; Risk Prediction |
| Parekh, Rulan S | Hospital for Sick Children (Toronto) University of Toronto |
Subvention de fonctionnement | Long-Term Survival in Childhood Solid Organ Transplants | Cancer; Cardiovascular Disease; Children; Chronic Diseases; Chronic Kidney Disease; Diabetes; Transplant |
| Parker, Thomas G | St. Michael's Hospital (Toronto) University of Toronto |
Subvention de fonctionnement | The role of the calcium-binding protein, S100B, in cardiovascular disease | Calcium-Binding Proteins; Myocardial Infarction; Transgenic Mice |
| Parks, Robin J | Ottawa Hospital Research Institute/Institut de recherche de l'Hôpital d'Ottawa University of Ottawa/Université d'Ottawa |
Subvention de fonctionnement | Regulation of innate immunity during development | Apoptosis; Development; Innate Immunity; Obesity; Type 2 Diabetes |
| Pastinen, Tomi | McGill University/Université McGill | Subvention de fonctionnement | Map of cis-regulatory variants in human genome | Epigenetics; Functional Variation; Gene Annotation; Genomics; Human Gene Expression; Polymorphisms |
| Paterno, Gary D | Memorial University of Newfoundland | Subv de fonct. - AP: Programme de partenariats régionaux-Terre Neuve et Labrador | MIER1 alpha, a novel PPAR gamma co-regulator, and its role in adipogenesis | Adipocyte Function; Adipogenesis; Conditional Knockout Mice; Diabetes; Fat Metabolism; Gene Expression; Microarray; Ppar Gamma; Protein Interaction; Transcriptional Regulator |
| Pause, Arnim P | McGill University/Université McGill | Subvention Projet | Interplay of AMPK and mTOR pathways at the lysosome: starvation, nutrient availability and metabolic disease | Ampk; Flcn; Metabolic Syndrome; Mtor; Obesity; Phosphorylation; Tfeb |
| Peng, Tianqing | London Health Sciences Centre Res. Inc. (Ont.) University of Western Ontario |
Subvention de fonctionnement | Transformation of normal to abnormal myocardium by diabetes mellitus: role of Rac1-mediated calpain activation | Calpain; Cardiomyopathy; Diabetes; Myocardial Function; Nadph Oxidase; Rac1 |
| Peng, Tianqing | London Health Sciences Centre Res. Inc. (Ont.) University of Western Ontario |
Subvention de fonctionnement | Calpain activation and diabetic cardiomyopathy | Apoptosis; Atp Synthase; Calpain; Cardiomyocytes; Cardiomyopathy; Diabetes; Heart; Mitochondria; Reactive Oxygen Species |
| Pernet, Vincent E | Université Laval | Subvention Projet | Mechanisms of neuronal and vascular impairments in ischemic retinopathies | Diabetic Retinopathy; Ischemic Retinopathies; Neuronal Repair; Nogo-A; Proliferative Retinopathy; Vascular Regeneration |
| Persaud, Navindra | St. Michael's Hospital (Toronto) University of Toronto |
Subv. de fonctionnement: Subv. pluriannuelle : essais clin. novateurs de la SRAP | CLEAN Meds RCT: Carefully seLected and Easily Accessible at No charge Medications | Equitable Access To Medication; Pharmaceutical Access; Prescription Medication; Rct |
| Phillips, Stuart M | McMaster University | Subvention de fonctionnement | Adjunctive nutritional strategies to overcome sarcopenic muscle loss in aging | Aging; Branched-Chain Amino Acids; Casein; Citrulline; Human; Milk Proteins; Protein Metabolism; Sarcopenia; Stable Isotope; Whey |
| Picard, Frédéric | Institut universitaire de cardiologie et de pneumologie de Québec - ULaval Université Laval |
Subvention Projet | Modulation and effects of IGFBP-2 on brown adipose tissue thermogenesis | Brown Adipose Tissue; Energy Expenditure; Gene Expression; Imaging Techniques; Insulin Sensitivity; Lipid Metabolism; Mice; Molecular Biology; Obesity; Thermogenesis |
| Picard, Frédéric | Institut universitaire de cardiologie et de pneumologie de Québec - ULaval Université Laval |
Subvention de fonctionnement | Transcriptional control of adipose tissue by OcaB upon aging | Adipocytes; Adipose Tissue; Aging; Bone Marrow Transfer; Energy Metabolism; Gene Expression; Insulin Resistance; Lymphocytes B; Mice; Nuclear Cofactors |
| Planel, Emmanuel | Université Laval | Subvention de fonctionnement | Impact of diabetes on tau pathogenesis in vivo | Alzheimer's Disease; Diabetes Mellitus; Tau Pathology; Transgenic Mouse Models |
| Ploeg, Jenny | McMaster University | Subv. de fonct.: Réseau de la SRAP sur les ISSIPL - subventions programmatiques | ACHRU Community Partnership Program for Diabetes Self-Management for Older Adults - Canada | Community-Based Care; Diabetes; Multiple Chronic Conditions; Older Adults; Patient-Oriented Research; Patients With Complex Needs; Pragmatic Trial; Primary Care; Self-Management |
| Poirier, Paul | Institut de cardiologie de Québec | Subvention de fonctionnement - AP : soins bariatriques (fin transitoire) | Impact of a 12-week structured training program on changes in body composition and insulin resistance after a biliopancreatic diversion with duodenal switch surgery in severe obesity | Bariatric Surgery; Body Composition; Exercise; Fat Mass; Insulin Resistance; Lean Mass |
| Poitout, Vincent | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention Projet | HB-EGF as a central regulator of pancreatic beta-cell proliferation | G Protein-Coupled Receptors; Growth Factors; Islets Of Langerhans; Pancreatic Beta Cell; Proliferation; Type 2 Diabetes |
| Poitout, Vincent | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention de fonctionnement | The role of RGS16 in pancreatic beta-cell function | Beta-Cell Biology; G-Protein Coupled Receptors; Glucose Homeostasis; Insulin Secretion |
| Poitout, Vincent | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention de fonctionnement | The role of GPR40 in pancreatic beta-cell function | Diabetes; G-Protein Coupled Receptors; Gpr40; Insulin Secretion; Islets Of Langerhans |
| Poitout, Vincent | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention Projet | Role and therapeutic potential of RGS16 in pancreatic beta cells | Beta-Cell Proliferation; G Protein-Coupled Receptors; Glucose Homeostasis; Insulin Secretion; Islet Of Langerhans; Pancreatic Beta-Cell |
| Poitout, Vincent | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention de fonctionnement | Glucolipodysfunction of the pancreatic beta-cell | Diabetes; Glucolipotoxicity; Insulin Gene; Islets Of Langerhans |
| Polychronakos, Constantin | Research Institute of the McGill University Health Centre/Institut de recherche du Centre universitaire de santé McGill McGill University/Université McGill |
Subvention Projet | Precision diagnostics in childhood diabetes; therapeutic implications | Diabetes; Dominant; Exome; Mendelian; Mody; Monogenic; Neonatal; Recessive |
| Power, Christopher | University of Alberta | Sub de fonctionnement: Recherche biomédicale/clinique novatrice sur le VIH/sida | Therapeutic effects of intranasal insulin on HIV-associated neurocognitive disorder | Biomarkers; Clinical Trial; Hiv-Associated Neurocognitive Disorder; Hiv/Aids; Intranasal Insulin |
| Prakash, Satya | McGill University/Université McGill | Subvention de fonctionnement | Polymeric membrane lactobacillus formulation for use in type II diabetes | Diabetes Mellitus; Feruloyl Esterase; Microcpsule; Polymeric Membrane |
| Prentki, Marc | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Programme de démonstration des principes - phase I | Validation of a glycerolipid/ free fatty acid cycling enzyme as a novel therapeutic target for type-2 diabetes | Drug Development; Insulin Secretion; Monoglyceride Lipase; Pancreatic Beta Cell; Type-2 Diabetes |
| Prentki, Marc | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention Fondation | Lipid metabolism, insulin secretion and energy homeostasis | Abhd6; Adipose Browning; Fuel Detoxification; Glycerol-3-Phosphatase; Glycerolipid/Free Fatty Acid Cycling; Insulin Secretion; Lipid Metabolism; Monoacylglycerol; Obesity; Pancreatic Beta Cell |
| Prentki, Marc | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention de fonctionnement | Molecular Basis of Fuel Surfeit Detoxification in Pancreatic beta-Cells | Fuel Detoxification; Glucolipotoxicity; Glycerolipid/Free Fatty Acid Cycling; Lipid Metabolism; Lipolysis; Pancreatic Beta Cell |
| Prentki, Marc | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention de fonctionnement | Glucose regulation of insulin secretion and metabolic enzymes' gene expression | Anaplerosis/ Cataplerosis; Glycerolipid/Free Fatty Acid Cycling; Insulin Secretion; Lipid Metabolism; Monoacylglycerol; Pancreatic Beta Cell |
| Proctor, Spencer D | University of Alberta | Subvention Projet | Efficacy of a novel idiotypic antibody to inhibit cholesterol retention in atherosclerotic vascular disease during insulin resistance and diabetes | Animal Models; Arterial Retention; Atherosclerosis; Chimeric Antibodies; Glycosaminoglycans; Human Derived Specimens; Idiotypic Antibodies; Remnant Lipoproteins |
| Punthakee, Zubin | McMaster University | Équipes de collaboration indo-canadiennes de recherche en obésité infantile | Overweight and obesity in Asian Indian children in India and Canada: multi-level determinants, functional consequences and novel mechanisms | Body Composition; Built Environment; Children And Youth; Cross-Sectional Study; Eating And Activity Behaviours; Family Environment; Indian Origin; Metabolic Effects; Obesity; Qualitative Studies |
| Qi, Dake | Memorial University of Newfoundland | Subvention Projet | Macrophage migration inhibitory factor (MIF), a novel factor regulates hyperphagia and obesity associated with atypical antipsychotics | Atyical Antipsychotics; Macrophage Migration Inhibitory Factor; Metabolic Dysfunction; Procytokine |
| Quaggin, Susan E | Lunenfeld-Tanenbaum Research Institute (Toronto) University of Toronto |
Subvention de fonctionnement | Factors that Protect the Vasculature in Diabetes | Angiopoietin; Cre-Loxp; Diabetic Nephropathy; Mtor; Retinopathy; Tie2; Transgenic Mice; Vegf |
| Rabi, Doreen M | University of Calgary | Subvention de fonctionnement | A Mixed-Methods Human Factors Evaluation of Patient Heath Portals in Diabetes | Chronic Disease Management; Diabetes; Ehealth |
| Raboud, Janet M | University Health Network (Toronto) University of Toronto |
Subv fonct - AP : VIH/sida Initiative de recherche - volet biomédicale/clinique | Development and Validation of an Algorithm to Impute Missing Stop Dates of Antiretroviral Therapy Regimens | Algorithm; Antiretroviral Therapy; Hiv/Aids; Imputation |
| Ramanathan, Sheela | Université de Sherbrooke | Subvention de fonctionnement | Regulation of obesity by inflammatory cytokines | Adipose Tissue; Chemokines; Chronic Inflammation; Interleukin-15; Macrophages; Mice; Obesity; Patients; T Lymphocytes; Thermogenesis |
| Ray, Joel G | St. Michael's Hospital (Toronto) University of Toronto |
Subv de fonct-AP : fonds de démarrage INMD (financement trans) -cliniciens | Abdominal visceral fat measured in early pregnancy and the risk of gestational diabetes mellitus | Gestational Diabetes Mellitus; Glucose Dysregulation; Insulin Resistance; Maternal Health; Metabolic Syndrome; Metabolism; Non-Alcoholic Fatty Liver Disease; Pre-Diabetes; Type 2 Diabetes Mellitus; Visceral Adiposity |
| Ray, Joel G | St. Michael's Hospital (Toronto) University of Toronto |
Subvention de fonctionnement | Abdominal visceral fat measured in early pregnancy as a novel and practical early predictor of gestational diabetes mellitus | Gestational Diabetes Mellitus; Glucose Dysregulation; Insulin Resistance; Maternal Health; Metabolic Syndrome; Metabolism; Pre-Diabetes; Type 2 Diabetes Mellitus; Visceral Adiposity |
| Rayner, Katey | University of Ottawa Heart Institute/Institut de cardiologie de l'Université d'Ottawa University of Ottawa/Université d'Ottawa |
Sub de fonctionnement - AP : ISCR nouveaux chercheurs (financement transitoire) | microRNA-33 Regulation of PGC-1alpha: Role in Atherosclerosis and Obesity | Atherosclerosis; Diabetes; Fatty Acid Metabolism; Inflammation; Microrna; Mitochondria; Obesity |
| Rayner, Katey | University of Ottawa Heart Institute/Institut de cardiologie de l'Université d'Ottawa University of Ottawa/Université d'Ottawa |
Subvention de fonctionnement | microRNA Regulation of PGC-1alpha: Role in Atherosclerosis and Obesity | Atherosclerosis; Diabetes; Fatty Acid Metabolism; Inflammation; Microrna; Mitochondria; Obesity |
| Reading, Stacey A | University of New Brunswick (Fredericton) | Partenariats pour l'amélioration du système de santé (PASS) | An Interprofessional Approach to Improving the Health of Obese Adults in New Brunswick | Chronic Disease; Exercise; Intervention Study; Obesity |
| Regnault, Timothy R | University of Western Ontario | Subvention de fonctionnement | In utero insults and adult insulin resistance | Epigenetic Regulation Of Muscle Development; In Vivo Fetal Hypoxia And Muscle Development; Mitochondrial Biogenesis And Oxidative Phosphorylation; Mtor And Muscle Oxidative Function; Origins Of Adult Diseases; Ppars And Muscle Energy Balance |
| Regnault, Timothy R | University of Western Ontario | Subvention Projet | Modulating the in utero environment to prevent later life insulin resistance | Fetus; Hypoxia; Insulin Resistance; Iugr; Low Birth Weight; Metabolic Syndrome; Muscle Mitochondria; Oxidative Stress; Placental Insufficiency; Pyrroloquinoline Quinone |
| Reimer, Raylene A | University of Calgary | Subvention de fonctionnement | Dietary manipulation of gut microbiota to manage obesity and insulin resistance | Gut Microbiota; Insulin Resistance; Maternal Health; Obesity; Pre-Conception; Prebiotic Fiber; Satiety Hormones; Sitagliptin |
| Reimer, Raylene A | University of Calgary | Subv. de fonct -AP : Inst. de la Nutrition, métabolisme, diabète -fin transit. | Dietary manipulation of gut microbiota to manage obesity and insulin resistance | Gut Microbiota; Insulin Resistance; Maternal Health; Obesity; Pre-Conception; Prebiotic Fiber; Satiety Hormones; Sitagliptin |
| Rorsman, Patrik | University of Alberta | Subvention de fonctionnement | Mechanisms by which long-term exposure to free fatty acids inhibit glucose-induced insulin secretion | Ca2+ Channels; Diabetes; Exocytosis; Free Fatty Acids; Insulin; Islets Of Langerhans |
| Reimer, Raylene A | University of Calgary | Subv. de fonct -AP : Inst. de la Nutrition, métabolisme, diabète -fin transit. | Dietary manipulation of gut microbiota to manage obesity and insulin resistance | Gut Microbiota; Insulin Resistance; Maternal Health; Obesity; Pre-Conception; Prebiotic Fiber; Satiety Hormones; Sitagliptin |
| Retnakaran, Ravi R | Sinai Health System (Toronto) University of Toronto |
Subvention de fonctionnement | Postpartum Progression to Type 2 Diabetes in Women with Recent Glucose Intolerance in Pregnancy: Pathophysiology, Biomarkers, and Clinical Implications | Beta-Cell Function; Gestational Diabetes Mellitus; Glucose Intolerance In Pregnancy; Type 2 Diabetes; Women's Health |
| Retnakaran, Ravi R | Sinai Health System (Toronto) University of Toronto |
Subvention Projet | Progression to Type 2 Diabetes in the 1st Decade after Glucose Intolerance in Pregnancy: Pathophysiology and Clinical Implications | Adiponectin; Gestational Diabetes; Glucose Tolerance; Pancreatic Beta-Cell Function; Postpartum; Type 2 Diabetes; Women's Health |
| Retnakaran, Ravi R | Sinai Health System (Toronto) University of Toronto |
Subvention de fonctionnement | Exenatide and Insulin Glargine Combination Therapy for the Preservation of Pancreatic Beta-cell Function in Early Type 2 Diabetes: A Randomized Controlled Trial | Basal Insulin; Beta-Cell Function; Clinical Trial; Combination Therapy; Glp-1; Type 2 Diabetes |
| Retnakaran, Ravi R | Sinai Health System (Toronto) University of Toronto |
Subvention de fonctionnement | A Pre-conception Cohort to Study Gestational Diabetes Mellitus: Pre-gravid Determinants, Early Pregnancy Bio-markers and Postpartum Cardio-metabolic Risk Factor Profile | Bio-Markers; Cardiovascular Risk; Clinical Research; Cohort Study; Gestational Diabetes; Pregnancy; Risk Factors; Women's Health |
| Retnakaran, Ravi R | Sinai Health System (Toronto) University of Toronto |
Subvention de fonctionnement | A Randomized Controlled Trial to Evaluate Early Intermittent Intensive Insulin Therapy as an Effective Treatment of Type 2 Diabetes | Clinical Trial; Insulin Therapy; Pancreatic Beta-Cell Function; Type 2 Diabetes |
| Rhodes, Ryan E | University of Victoria (British Columbia) | Subvention de fonctionnement | Evaluation of a Physical Activity Intervention for New Parents | Parenthood; Physical Activity |
| Richard, Caroline | University of Alberta | Subvention Projet | Establishing the importance of diet and insulin resistance in modulating immune function in obesity | Clinical Trial; Diet; Immune Function; Inflammation; Insulin Resistance; Obesity; T Cells; Type 2 Diabetes |
| Richard, Denis | Institut universitaire de cardiologie et de pneumologie de Québec - ULaval Université Laval |
Subvention de fonctionnement | The role of DEPTOR in Energy Balance Regulation | Brain; Energy Homeostasis; Food Intake; Hypothalamus; Melanocortin System; Mtorc1; Neuropeptide Y; Proopiomelanocortin; Steroidogenic Factor 1; Thermogenesis |
| Richards, Brent | Lady Davis Institute for Medical Research (Mtl) McGill University/Université McGill |
Subvention de fonctionnement | Mendelian randomization: Testing the causality of clinically-relevant biomarkers | Autoimmunity; Genetic Epidemiology; Gwas; Mendelian Randomization; Vitamin D |
| Rideout, Elizabeth J | University of British Columbia | Subvention Projet | Identifying genes and regulatory pathways that control sex differences in lipid storage using Drosophila as a model. | Adipose Tissue/Fat Body; Beta-Adrenergic/Adipokinetic Hormone Signaling Pathways; Drosophila Genetics; Ectopic Lipid Droplet Accumulation; Insulin Gene Transcription; Insulin Secretion; Insulin Signaling Pathway; Lipid Droplet Biology; Lipogenesis And Lipolysis; Physiology |
| Riediger, Natalie D | University of Manitoba | Subvention Projet | Sticky money: Exploring the acceptability of a sugar-sweetened beverage tax among Canadian Indigenous populations | Colonialism; Diabetes; Equity; First Nation; Indigenous; Obesity; Policy; Stigma; Sugar-Sweetened Beverage Tax; Youth |
| Riediger, Natalie D | University of Manitoba | Subvention de fonctionnement: ESCC - Analyse de la nutrition | A Call to Action towards food equity: Measuring obesity, diet quality, and food security disparities between Indigenous and non-Indigenous populations, 2004 vs. 2015 | Diet Quality; Food Security; Health Equity; Indigenous Health; Obesity; Socioeconomic Status |
| Rocheleau, Jonathan V | University Health Network (Toronto) University of Toronto |
Subvention Projet | Determining the impact of metabolic heterogeneity on the proliferation and survival of pancreatic beta-cells. | Beta-Cell; Genetically Encoded Sensors; Live Cell Imaging; Metabolism; Microfluidic Devices; Nadh; Nadph; Proliferation; Survival |
| Rocheleau, Jonathan V | University Health Network (Toronto)University of Toronto | Subv. de fonct -AP : Inst. de la Nutrition, métabolisme, diabète -fin transit. | Endocrine FGFR1 signaling in the pancreatic beta-cell: association with Klotho-beta co-receptor and FGFRL1 decoy receptor. | Beta-Cell; Fgf21; Fgfr1; Fgfrl1; Klotho-Beta; Pancreatic Islet |
| Rodrigues, Brian B | University of British Columbia | Subvention de fonctionnement | Endothelial heparanase regulation of cardiac metabolism | Cardiac Metabolism; Heparanase; Lipoprotein Lipase; Lipotoxicity; Vegf |
| Rodrigues, Brian B | University of British Columbia | Subvention de fonctionnement | Regulation of endothelial heparanase following diabetes | Cardiac Metabolism; Endothelial Cells; Fatty Acid; Heparanase; Hyperglycemia; Lipoprotein Lipase |
| Rogers, Ian M | Sinai Health System (Toronto) University of Toronto |
Programme de démonstration des principes - phase I | The Use of Multipotential Stem Cells for the Treatment of Peripheral Vascular Disease | Bone Marrow; Hematopoietic; Ischemias; Peripheral Vascular Disease; Stem Cells |
| Rose, David R | University of Waterloo (Ontario) | Subvention de fonctionnement | Molecular Mechanism of Intestinal Glycosidases: Nutritional Starch Digestion and Regulation of Blood Glucose Levels | Carbohydrate Chemistry; Diabetes; Glycosidase Mechanism; Nutritional Starch Metabolism; Obesity; Protein Structure |
| Rose, Robert A | Dalhousie University (Nova Scotia) | Subvention de fonctionnement | Impaired regulation of sinoatrial node function and atrial arrhythmogenesis in the diabetic heart | Atrial Fibrillation; Autonomic Nervous System; Diabetes Mellitus; Electrophysiology; Insulin Signaling; Ion Channels; Molecular Biology; Optical Mapping; Pi3k; Sinoatrial Node |
| Rosella, Laura C | Ontario Agency for Health Protection and Promotion (Toronto, Ontario) | Subvention de fonctionnement | Maximizing population benefit and impact by applying population risk tools: A new direction for diabetes prevention in Canada | Decision-Making Tools; Diabetes; Epidemiology; Obesity; Population Risk Tools |
| Rosella, Laura C | Ontario Agency for Health Protection and Promotion (Toronto, Ontario)/L'Agence ontarienne de protection et de promotion de la santé University of Toronto |
Subv fonct-AP : fonds de démarrage INMD (finance trans) -professeurs adjoint | Quantifying future risk and burden of type 2 diabetes in Canada: tools to inform the prevention of obesity and diabetes | Administrative Databases; Decision-Making Tools; Diabetes; Epidemiology; Multilevel Growth Models; Obesity; Population Risk Tools; Population Surveys; Survival Analysis |
| Rosella, Laura C | Ontario Agency for Health Protection and Promotion (Toronto, Ontario)/L'Agence ontarienne de protection et de promotion de la santé University of Toronto |
Subvention de fonctionnement : des connaissances à la pratique | Supporting diabetes population health risk tools in practice: Partnerships to guide adaption, implementation and evaluation | Case Study; Diabetes; Integrated Knowledge Translation; Knowledge To Action; Knowledge Translation; Mixed Methods; Population Risk Tools; Risk Algorithms |
| Rosenberg, Lawrence | McGill University/Université McGill | Programme de démonstration des principes - phase II | A Novel Regenerative Drug Therapy to Restore Natural Insulin Secretion in Diabetes Mellitus | Diabetes Melitus; Drug Discovery; Ingap Analogues; Ingap-Islet Neogenesis Associated Protein; Islet Neogenesis |
| Ross, Nancy A | McGill University/Université McGill | Subvention de fonctionnement: ESCC - Analyse de la nutrition | Does Neighbourhood Food Environment Amplify Canadian Social Inequalities in Diet, Health and Food Insecurity? | Dietary Recall; Food Insecurity; Retail Food Environments; Social Inequalities In Health; Type 2 Diabetes |
| Rost, Hannes L | University of Toronto | Subvention Projet | A novel approach for personalized metabolomics profiling using DIA mass spectrometry | Diabetes; Mass Spectrometry; Metabolomics; Method Development; Personalized Medicine; Systems Medicine |
| Rotondi, Michael A | York University (Toronto, Ontario) | Subvention de fonctionnement | Aboriginal Health Counts: Advancing multivariable methods for respondent driven sampling | Aboriginal Health; Cardiovascular Disease; Chronic Conditions; Correlated Data Analysis; Diabetes; Hypertension; Multivariable Methods; Respondent-Driven Sampling |
| Rozakis-Adcock, Maria | University of Toronto | Subvention de fonctionnement | Role of PHIP in the Hormonal Control of Liver Gluconeogenic Networks | Genetic Animal Models; Insulin/Glucagon; Liver; Pgc1/Torc2 Pathway; Transcriptional Regulation |
| Rudkowska, Iwona | Université Laval | Subvention Projet | Nutrigenomic approach to investigate the benefits of dairy product consumption on glucose homeostasis | Dairy Products; Gene-Diet Interactions; Glucose-Insulin Homeostasis; Metabolomics; Nutrigenomics; Personalized Nutrition; Transcriptomics; Type 2 Diabetes |
| Sairam, M. R | Institut de recherches cliniques de Montréal Université de Montréal |
Subvention de fonctionnement | Discovery of Estrogen Mediated Fat Depot Specific Genes: Implications for Obesity and Metabolic Syndrome | Adipocytes; Adipokines; Aging; Gene Changes & Cloning; Inflammation; Sex Hormone Imbalances |
| Salbach, Nancy | University of Toronto | Subvention Projet | Getting Older adults OUTdoors (GO-OUT): A randomized controlled trial of a community-based outdoor walking program | Accelerometry/Gps; Community; Health-Related Quality Of Life; Knowledge Translation; Older Adult; Physical Activity; Qualitative; Randomized Controlled Trial; Walking Outdoors |
| Saleh, Maya | McGill University/Université McGill | Subvention Projet | Genetic and functional analyses of the inflammatory caspases and inflammasomes in obesity, metabolic inflammation and insulin resistance | Caspases; Inflammasome; Inflammation; Insulin Resistance; Metabolism; Obesity |
| Santerre, Paul | University of Toronto | Subvention de fonctionnement | Monocyte directed tissue regeneration of a blood vessel substitute using a pro-cellular degradable tubular scaffold | Angiogenesis; Biomechanics; Endothelial Cells; In Vivo; Monocytes; Polymeric-Biomaterials; Stem Cells; Tissue Engineering; Vascular Grafts; Vascular Smooth Muscle Cells |
| Sapieha, Przemyslaw (Mike) S | CIUSSS Est-de-l'Ile-de- Montréal-Maisonneuve Rosemont Université de Montréal |
Subvention de fonctionnement | Neuronal derived Semaphorin 3A contributes to vascular degeneration and misdirected pathological vessel growth in proliferative ischemic retinopathies | Angiogenesis; Endothelial Cell; Guidance Cues; Proliferative Retinopathies; Retinal Ganglion Cells; Semaphorin |
| Sarunic, Marinko V | Simon Fraser University (Burnaby, B.C.) | Subvention Projet | Sensorless Adaptive Optics Optical Coherence Tomography for Clinical Ophthalmology | Adaptive Optics; Age-Related Macular Degeneration (Amd); Cellular Resolution; Diabetic Retinopathy; Dry Amd; Imaging; Ophthalmology; Optical Coherence Tomography (Oct); Vision; Wavefront Sensorless Adaptive Optics |
| Sarunic, Marinko V | Simon Fraser University (Burnaby, B.C.) | Subvention Projet | Sensorless Adaptive Optics Optical Coherence Tomography for Clinical Ophthalmology | Adaptive Optics; Age-Related Macular Degeneration; Dry Amd; Glaucoma; Imaging; Ophthalmology; Optical Coherence Tomography; Vision; Wavefront Sensorless Adaptive Optics |
| Sauve, Yves | University of Alberta | Subvention de fonctionnement | Retinopathy in a Cone-Rich Rodent Model of Spontaneous Type 2 Diabetes | Animal Model; Diabetic Retinopathy; Early Screening; Electrophysiology; Mechanisms Of Retina Degeneration And Dha Therapeutic Action; Nutrition; Vision Loss; Visual Function |
| Schertzer, Jonathan D | McMaster University | Subvention Fondation | Microbiota and inflammatory triggers of metabolic disease | Diabetes; Immunometabolism; Microbiota; Obesity |
| Schertzer, Jonathan D | McMaster University | Subvention de fonctionnement | NOD1 and NOD2 immunity regulate obesity-induced inflammation and insulin resistance | Adipocytes; Cell Biology; Diabetes; Glucose; Gut Bacteria; Immunity; Inflammation; Insulin Resistance; Metabolic Disease; Obesity |
| Schertzer, Jonathan D | McMaster University | Subv de fonct- AP : Fonds de démarrage INMD (finance trans)-nouveaux chercheurs | NOD2 immunity protects against obesity-induced inflammation and insulin resistance | Cell Biology; Diabetes; Glucose; Gut Bacteria; Immunity; Inflammation; Insulin; Metabolic Disease; Obesity; Physiology |
| Schiffrin, Ernesto L | CIUSSS de Centre-Ouest-de-l'Ile-de-Montréal-Jewish General/CIUSSS de Centre-Ouest-de-l'Ile-de-Montréal-Hôpital juif McGill University/Université McGill |
Subvention Fondation | Vascular remodeling in hypertension and cardiometabolic disease: from mice to humans | Angiotensin; Blood Vessels; Endothelin; Endothelium; Inflammation And Immunity; Intracellular Signaling And Oxidative Stress; Microrna And Messenger Rna; Molecular Biology; Pharmacology; Smooth Muscle Cells |
| Schmitz, Norbert | CIUSSS de l'Ouest-de-l'Ile-de-Montréal-Douglas Hospital/CIUSSS de l'Ouest-de-l'Ile-de-Montréal-Hôpital Douglas McGill University/Université McGill |
Subvention de fonctionnement | Psychological problems associated with transition to insulin therapy in people with type 2 diabetes | Anxiety; Community Study; Coping; Depression; Diabetes; Epidemiology |
| Schmitz, Norbert | Douglas Mental Health University Institute (Montreal, QC)/Douglas Institut Universitaire en Santé Mentale | Subvention de fonctionnement | Depression as a risk factor for type 2 diabetes: role of metabolic factors | Community Study; Depression; Diabetes; Metabolic Factors; Prospective Study |
| Schmitz, Norbert | CIUSSS de l'Ouest-de-l'Ile-de-Montréal-Douglas Hospital/CIUSSS de l'Ouest-de-l'Ile-de-Montréal-Hôpital Douglas McGill University/Université McGill |
Subvention de fonctionnement | Depression and disability in diabetes: a prospective community study | Community Sample; Depression; Diabetes; Disability; Longitudinal Relationship |
| Schricker, Thomas Peter S | Research Institute of the McGill University Health Centre/Institut de recherche du Centre universitaire de santé McGillMcGill University/Université McGill | Subvention de fonctionnement | Enhancing the anabolic effect of perioperative nutrition by insulin and maintenance of normoglycemia | Colorectal Cancer Surgery; Insulin Therapy; Muscle Physiology; Normoglycemia; Perioperative Nutrition; Protein Metabolism; Stable Isotope Tracer Studies |
| Schultz, Annette S | University of Manitoba | Subvention Projet | Indigenous People and Diabetes - Indigenous Knowledge and Wellness Practices disrupting Biomedical Colonization: Research Governed by Decolonizing and Two-Eyed Seeing Methods | Canada; Food And Type Two Diabetes; Food Sovereignty; Healthcare Services; Indigenous Health; Indigenous Knowledges |
| Schwartzman, Kevin | Research Institute of the McGill University Health Centre/Institut de recherche du Centre universitaire de santé McGill McGill University/Université McGill |
Subvention de fonctionnement | Preventing tuberculosis in Inuit communitiies: Predicting what may work | Cost-Effectiveness Analysis; Decision Analysis; Inuit; Social Determinants; Transmission Model; Tuberculosis |
| Schwartzman, Kevin | Research Institute of the McGill University Health Centre/Institut de recherche du Centre universitaire de santé McGill McGill University/Université McGill |
Subv de fonct - AP : santé des Premières nations, des Inuits et/ou des Métis | Modeling the impact of interventions for tuberculosis control in Inuit communities | Cost-Effectiveness Analysis; Decision Analysis; Inuit; Social Determinants; Tuberculosis |
| Schwertani, Adel G | Research Institute of the McGill University Health Centre/Institut de recherche du Centre universitaire de santé McGill McGill University/Université McGill |
Subvention de fonctionnement | Significance of the urotensin II system in the cardiovascular abnormalities of the metabolic syndrome | Cardiovascular Function; Drug Research; Gene Knockout; Hypertension; Immunoassay; Morphology; Obesity; Receptor Antagonists; Rt-Pcr; Western Blotting |
| Scott, Mark D | University of British Columbia | Subvention de fonctionnement | Polymer-Grafted Allogeneic Leukocytes and Systemic Immune Modulation | Bioengineering; Lymphocyte; Polymer |
| Screaton, Robert A | Children's Hospital of Eastern Ontario Research Institute Inc/Institut recherche Centre hospitalier pour enfants de l'est de l'Ontario University of Ottawa/Université d'Ottawa |
Subvention de fonctionnement | Role of MARK2:TORC2:CREB signaling in beta cell regeneration | Ampk Kinase Family; Beta Cell Regeneration; Beta Cells; Conditional Knockout; Creb; Torc2/Crtc2 |
| Screaton, Robert A | Sunnybrook Research Institute (Toronto, Ontario) University of Toronto |
Subvention de fonctionnement | Novel Regulators of Mitochondrial Dynamics | Apoptosis; Cell Signaling; Knockout Mouse Models; Mitochondria; Mitochondrial Dynamics; Mitophagy; Neurons; Pancreatic Beta Cells; Parkin; Romo1 |
| Screaton, Robert A | Children's Hospital of Eastern Ontario Research Institute Inc | Subvention de fonctionnement | The role of LKB1 in beta cell biology | Ampk; Beta Cells; Gene Expression Analysis; Glucose Metabolism; Insulin Secretion; Islets; Lkb1; Signal Transduction; Type 1 Diabetes; Type 2 Diabetes |
| Seguin, Cheryle A | University of Western Ontario | Subv de fonct - AP : fonds de démarrage de l'INMD (financement provisoire) | Directed differentiation of pancreatic islet precursors from pluripotent human stem cells | Cell Differentiation; Diabetes; Human Embryonic Stem Cells; Islet Cell Replacement / Engineering; Lineage Specification; Transcription Factor |
| Shah, Baiju R | Institute for Clinical Evaluative Sciences-Toronto University of Toronto |
Subv de fonctionnement : rech interventionnelle en santé des populations | Evaluation of a strategy to improve cardiovascular disease screening and treatment for people with diabetes | N/A |
| Shah, Baiju R | Sunnybrook Research Institute (Toronto, Ontario) University of Toronto |
Subv de fonct-AP : fonds de démarrage INMD (financement trans) -cliniciens | Microalbuminuria and Retinopathy in Gestational Diabetes: The MARIGOLD Study | Gestational Diabetes; Metabolic Function; Microalbuminuria; Microvascular Complications; Pregnancy; Retinopathy |
| Shah, Baiju R | Institute for Clinical Evaluative Sciences-Toronto University of Toronto |
Subvention Projet | Derivation of risk prediction models and a computer microsimulation model in type 2 diabetes to aid clinical decision making and health technology assessment. | Complications; Cost Effectiveness; Long-Term Outcomes; Microsimulation Models; Patient-Centred Care; Risk Prediction; Type 2 Diabetes |
| Shah, Baiju R | Sunnybrook Research Institute (Toronto, Ontario) University of Toronto |
Subvention de fonctionnement | Microalbuminuria and Retinopathy in Gestational Diabetes: The MARIGOLD Study | Gestational Diabetes; Metabolic Function; Microalbuminuria; Microvascular Complications; Pregnancy; Retinopathy |
| Shah, Baiju R | Institute for Clinical Evaluative Sciences-Toronto University of Toronto |
Subvention Projet | A pilot pragmatic randomized controlled trial to evaluate the impact of improving access to drugs on type 2 diabetes care, outcomes and costs | Acces To Medications; Diabetes Mellitus; Health Equity; Pilot And Feasibility Study; Randomized Controlled Trial |
| Sharma, Sangita | University of Alberta | Subvention Projet | Culturally Appropriate Practical Solutions Relevant to Indigenous Seniors and Caregivers Of Remote Northern Communities (CAPRICORN) | Caregivers; Elder Care; Health; Indigenous Health; Northern Canada; Seniors |
| Shen, Garry X | University of Manitoba | Subvention Projet | Promotion of breastfeeding for preventing type 2 diabetes and obesity in First Nations mothers and children in communities | Barrier Reduction; Breastfeeding; First Nations; Lifestyle Education; Nutrition; Pregnant And Postpartum Women; Rural And Remote Communities; Smartphone |
| Shen, Garry X | University of Manitoba | Subvention Projet | To determine the impact of breastfeeding, maternal food intake and infant gut microbiota on the risk of obesity and diabetes in First Nations women and children in rural communities | Breastfeeding; Children; Diabetes; First Nations Mothers; Gut Microbiome; Healthy Food Intake; Metabolomics Analysis; Obesity; Pregnancy; Rural And Remote Communities |
| Shen, Garry X | University of Manitoba | Subvention de fonctionnement - Analyse secondaire des bases de données | Impact of diabetes during pregnancy and breastfeeding on subsequent diabetes in First Nations mothers and children | Breastfeeding; Children And Adolescents; First Nations People; Gestational Diabetes; Pregnancy; Secondary Analysis Of Databases; Type 2 Diabetes |
| Sherifali, Diana T | McMaster University | Subvention de fonctionnement | Evaluating the Effect of a Diabetes Health Coach in Individuals with Type 2 Diabetes. | Community; Diabetes Health Coach; Randomized Controlled Trial; Self-Management Education; Self-Management Support |
| Sievenpiper, John L | University of Toronto | Subvention de fonctionnement: Le sucre et la santé | A randomized controlled trial of the effect of replacing sugar-sweetened beverage with non-nutritive sweetened beverage or water on gut microbiome and metabolic outcomes: Strategies To OPpose SUGARS with Non-nutritive sweeteners Or Water (STOP SUGARS NOW) trial | Gut Microbiome; Non-Nutritive Sweetened Beverages; Randomized Clinical Trial; Sugar-Sweetened Beverage |
| Simpson, Scot H | University of Alberta | Subvention de fonctionnement | Is there a dose-response relationship between glyburide and cardiovascular outcomes? | Cardiovascular Disease; Diabetes; Dose-Response Relationship; Multivariate Cox Proportional Hazards; Population-Based Observational Study; Sulfonylureas (Glyburide); Time-Dependent Drug Exposure |
| Sinal, Christopher J | Dalhousie University (Nova Scotia) | Subvention de fonctionnement | Differential Actions of the Novel Adipokine Chemerin Signaling Through Multiple Receptors | Adipocyte; Adipokine; Diabetes; Gene Regulation; Obesity; Pharmacology |
| Siu, Samuel C | University of Western Ontario | Subvention de fonctionnement | Pregnancy and Subsequent Cardiovascular Risk in Women with Heart Disease | Atherosclerosis; Cardiovascular Risk Factors; Pregnancy |
| Sladek, Robert G | McGill University/Université McGill | Subvention de fonctionnement | Functional characterization of susceptibility loci for Type 2 Diabetes Mellitus | Chromatin Structure; Diabetes Genetics; Diabetes Pathogenesis; Functional Genomics; Gene Expression; Transcription Factors |
| Sladek, Robert G | Research Institute of the McGill University Health Centre/Institut de recherche du Centre universitaire de santé McGill McGill University/Université McGill |
Subvention de fonctionnement | Functional characterization and fine mapping of a type 2 diabetes risk locus near IRS1. | Chromatin Structure; Diabetes Genetics; Diabetes Pathogenesis; Functional Genomics; Gene Expression; Transcription Factors |
| Sladek, Robert G | Research Institute of the McGill University Health Centre/Institut de recherche du Centre universitaire de santé McGill McGill University/Université McGill |
Subvention de fonctionnement | Integrated proteomics and genomics approach to characterize a risk locus for type 2 diabetes | Beta Cell Physiology; Common Genetic Variants; Diabetes Genetics; Diabetes Pathogenesis; Functional Genomics; Gene Expression; Protein Networks; Proteomics; Rare Genetic Variants; Transcription Factors |
| Smith, Peter M | Institute for Work & Health (Toronto) University of Toronto |
Subvention de fonctionnement | Developing a gender/sex-sensitive understanding of how the psychosocial work environment is related to chronic disease | Gender; Psychosocial Work Environment; Stress |
| Smith, Peter M | Institute for Work & Health (Toronto) University of Toronto |
Subvention de fonctionnement | A longitudinal examination of the relationship between immigrant labour market experiences, health behaviours and the incidence of diabetes and hypertension | Diabetes; Hypertension; Immigrants; Labour Market Experiences |
| Sokolowski, Marla B | University of Toronto | Subvention de fonctionnement | Analyses of the multiple functions of the Drosophila foraging gene: a cGMP dependent protein kinase | Drosophila; Fat; Foraging Behaviour; Learning And Memory; Neurogenetics; Pleiotropy |
| Song, Weihong | University of British Columbia | Subvention de fonctionnement | The role of RCAN1 in Alzheimer pathogenesis | Alzheimer's Disease; Amyloid Beta Protein; Diabetes; Drug Dedevelopment; High Glucose; Neuronal Apoptosis; Racn1; Transgeneic Mice |
| Sorisky, Alexander M | Ottawa Hospital Research Institute/Institut de recherche de l'Hôpital d'Ottawa University of Ottawa/Université d'Ottawa |
Subvention de fonctionnement | Atherogenic adipocyte dysfunction induced by TSH | Adipocyte Biology; Cardiovascular Disease; Inflammation; Tsh Signaling |
| Stambolic, Vuk | Princess Margaret Cancer Centre (Toronto) University of Toronto |
Subvention Projet | Molecular mechanism of insulin receptor action in breast cancer with implications for therapy | Breast Cancer; Cell Biology And Biochemistry; Insulin Receptor; Molecular Mechanism; Mouse Transgenic And Knockout Models; Obesity; Receptor Crosstalk; Retrospective Analysis Of Clinical Trials; Signal Transduction; Xenograft |
| Stanford, William L | Ottawa Hospital Research Institute/Institut de recherche de l'Hôpital d'Ottawa University of Ottawa/Université d'Ottawa |
Subvention de fonctionnement | Characterizing the function of ZBTB8A in adipogenesis and its requirement for normal metabolism | Adipogenesis; Chip-Seq; Knockout Mice; Metabolic Dysfunction; Mouse Models Of Disease; Obesity; Rna-Seq; Systems Biology; Transcriptional Regulation |
| Steinberg, Gregory R | McMaster University | Subvention de fonctionnement | Role of AMP-activated protein kinase in regulating inflammation in obesity: implications for the treatment of insulin resistance | Acetyl-Coa Carboxylase; Amp-Activated Protein Kinase; Fatty Acids; Inflammation; Innate Immunity; Insulin Resistance; Macrophage; Mouse Models; Obesity; Pgc1 And Mitochondria |
| Steinberg, Gregory R | McMaster University | Subvention de fonctionnement | SOCS3 regulation of insulin and leptin sensitivity in obesity | Amp-Activated Protein Kinase; Insulin Resistance; Leptin Resistance; Metabolism; Obesity; Suppressor Of Cytokine Signaling |
| Steinberg, Gregory R | McMaster University | Subvention Projet | Inhibition of Peripheral Serotonin for Treating Obesity | Beige Adipose Tissue; Brown Adipose Tissue; Energy Expenditure; Inflammation; Insulin Resistance; Non-Alcoholic Fatty Liver Disease; Obesity; Type 2 Diabetes |
| Steinberg, Gregory R | McMaster University | Programme de démonstration des principes - phase I | Development of a new therapy targeting adipose tissue metabolism for the treatment of obesity | Brown Adipose Tissue; Energy Expenditure; Obesity; Serotonin; Tryptophan Hydroxylase 1 |
| Steinberg, Gregory R | McMaster University | Subvention de fonctionnement | Skeletal Muscle Energy Sensing and Insulin Sensitivity in Obesity | Amp-Activated Protein Kinase; Fatty Acid Oxidation; Insulin Resistance; Metformin; Mouse Models; Obesity; Protein Acetylation; Protein Phosphorylation; Salicylate; Type 2 Diabetes |
| Steinberg, Gregory R | McMaster University | Subvention Fondation | Energy Sensing and Metabolism: From Mechanisms to New Therapies | Cardiovascular Disease; De Novo Lipogenesis; Endocrinology; Energy Expenditure; Insulin Resistance; Metabolism; Non-Alcoholic Fatty Liver Disease (Nafld); Non-Alcoholic Steahepatitis; Obesity; Type 2 Diabetes |
| Stone, Scot J | University of Saskatchewan | Subv. de fonct -AP : Inst. de la Nutrition, métabolisme, diabète -fin transit. | The role of DGAT2 in triacylglycerol synthesis and lipid droplet formation | Adipocyte; Lipid Biochemistry; Lipid Droplet; Obesity; Proteasome; Protein Interaction; Structure/Function; Subcellular Localization; Triacylglycerol; Ubiquitination |
| Stone, Scot J | University of Saskatchewan | Subv. de fonct.-AP-Programme de partenariats régionaux - Saskatchewan | The role of DGAT2 in triacylglycerol synthesis and lipid droplet formation | Adipocyte; Lipid Biochemistry; Lipid Droplet; Obesity; Proteasome; Protein Interaction; Structure/Function; Subcellular Localization; Triacylglycerol; Ubiquitination |
| Strachan, Shaelyn M | University of Manitoba | Subvention Projet | Examining the impact of a self-compassion intervention on physical activity behaviour among people with prediabetes: A pilot and feasibility study | Accelerometers; Exercise Psychology; Experimental Design; Feasibility Trial; Intervention; Mixed Methods; Physical Activity; Pilot Study; Self-Compassion; Self-Regulation |
| Strug, Lisa J | Hospital for Sick Children (Toronto) University of Toronto |
Subvention de fonctionnement | Modification of Cystic Fibrosis Phenotypes in the Pancreas and Gut | Association; Cystic Fibrosis; Diabetes; Gene Modifiers; Heritability; Intestinal Obstruction; Modifiers; Pancreatic Function; Population-Based Study; Statistical Genetics |
| Strumpf, Erin C | McGill University/Université McGill | Subvention de fonctionnement | Are Primary Care Teams effective? Evidence from Quebec's Family Medicine Groups on preventive care and from patients with multiple chronic conditions | Causal Inference With Observational Data; Co-Morbidity; Efficiency Of Health Care Services; Health Care Costs; Health Care Services Utilization; Population Health; Prevention; Primary Care; Primary Care Reform |
| Sung, Hoon Ki | Hospital for Sick Children (Toronto) University of Toronto |
Subvention Projet | Reversal of Adipose Fibrosis by Intermittent Fasting and VEGF | Adipocyte Precursor Cell; Adipose Fibrosis; Intermittent Fasting; Vascular Endothelial Growth Factor-A |
| Suuronen, Erik | University of Ottawa Heart Institute/Institut de cardiologie de l'Université d'Ottawa University of Ottawa/Université d'Ottawa |
Subv de fonct - AP : fonds de démarrage de l'INMD (financement provisoire) | Progenitor Cell Function in Defective Ischemia-induced Neovascularization in Diabetes | Advanced Glycation End Products; Diabetes; Endothelial Progenitor Cells; Ischemia; Neovascularization |
| Swardfager, Walter L | Sunnybrook Research Institute (Toronto, Ontario) University of Toronto |
Subvention Projet | Neurocognitive effects of osteocalcin in type 2 diabetes | Cognition; Diabetes; Exercise; Insulin Resistance; Metabolism; Osteocalcin |
| Sweeney, Gary | York University (Toronto, Ontario) | Subvention de fonctionnement | Regulation of skeletal muscle metabolism by adiponectin | Adiponectin; Diabetes; Fatty Acid Uptake And Metabolism; Glucose Transport And Metabolism; Insulin; Obesity |
| Szaszi, Katalin | St. Michael's Hospital (Toronto) University of Toronto |
Subvention de fonctionnement | TNF-alpha-induced Rho signaling and its role in intercellular junction regulation in kidney tubular cells | Cytoskeleton And Myosin; Epithelial Junctions; Fluorescent Microscopy; Transepithelial Permeability Measurements; Tubulointerstitial Inflammation; Tumor Necrosis Factor |
| Takano, Tomoko | McGill University/Université McGill | Subvention de fonctionnement | Role of protein phosphatase 1B in glomerular podocyte function | Glomerular Podocytes; Nephrin; Protein Tyrosine Phosphatase; Proteinuria |
| Takano, Tomoko | McGill University/Université McGill | Subvention de fonctionnement | Mechamisms of glomerular barrier dysfunction | Glomerular Podocytes; Proteinuria; Rho-Gtpases; Transgenic Mice |
| Tarasuk, Valerie S | University of Toronto | Operating Grant: Programmatic Grants to tackle health and health equity | Identifying policy interventions to reduce household food insecurity. | Burden Of Illness Methodology; Food Insecurity; International Comparison; Intervention Research; Policy Analysis; Secondary Data Analysis |
| Tarnopolsky, Mark A | McMaster University | Subvention Fondation | Characterization of novel exersomes that mediate the systemic pro-metabolic effects of exercise in aging and neuromuscular disorders. | Aging; Endurance Exercise; Exosomes; Neuromuscular Disorders; Proteomics; Rna-Sequencing; Skeletal Muscle; Systemic Humoral Factors; Systemic Mitochondrial Metabolism; Type 2 Diabetes |
| Tarride, Jean-Eric | McMaster University | Subvention de fonctionnement | Costs, health-related quality of life and cost-effectiveness of bariatric surgeries in Canada: an analysis of the Bariatric Registry | Bariatric Surgery; Bariatric Treatment; Co-Morbidities; Cost Burden; Morbid Obesity; Productivity Analysis; Return On Investment; Treatment Of Obesity |
| Taubert, Stefan | University of British Columbia | Subvention de fonctionnement | Metabolic regulation by a network centered on a conserved Mediator subunit | Gene Expression/ Transcription; Genetics Of Regulatory Networks; Lipid Metabolism; Stress Response / Detoxification |
| Taubert, Stefan | University of British Columbia | Subvention Projet | Function of the Mediator complex in pancreatic islet cell maturation and maintenance | Beta Cells; Diabetes; Gene Regulation; Hesc; Maturation; Mediator Complex; Pancreas; Stress; Transcription; Transplantation |
| Taylor, Jennifer P | University of Prince Edward Island (Charlottetown) | Sub fonct: équipe rech la mise en œuvre des voies de l'équité - composantes 1 | Food is Medicine: Addressing Obesity and Diabetes by Building Food Security and Food Sovereignty Among Prince Edward Island First Nations | Best Practices Review; Community Consultation; Diabetes; First Nations; Food Security; Food Sovereignty; Obesity |
| Tchernof, André | Université Laval | Subvention de fonctionnement | Adipose tissue prostaglandins as mediators of disease in women with male-pattern obesity | Adipose Tissue; Cell Biology; Obesity; Prostaglandins; Visceral Obesity; Women |
| Tchernof, André | Université Laval | Subvention de fonctionnement | Androgen inactivation and aldo-keto reductases 1C in adipose cells | Adipocyte; Aldo-Keto Reductase; Androgens; Androstanediol; Dihydrotestosterone; Obesity |
| Tchernof, André | Centre hospitalier de l'Université Laval (Québec) Université Laval |
Subvention de fonctionnement | Modulation of the androgenic message in adipose tissue | 5alpha-Reductases; Adipocyte; Androgens; Dihydrotestosterone; Obesity; Testosterone |
| Thompson, Jennifer A | University of Calgary | Subvention Projet | Metabolic disorders of pregnancy and early-onset disease risk in the offspring: role of adipose tissue expandability | Fetal Development; Fetal Programming; Gestational Diabetes; Maternal Obesity; Metabolic Disease |
| Tieleman, Peter D | University of Calgary | Subvention de fonctionnement - AP : Inst de génétiques (financement provisoire) | Computer simulations of ABC transporters | Abc Transporters; Cancer; Cystic Fibrosis; Molecular Dynamics Simulation; Molecular Modeling; Multidrug Resistance |
| Timmons, Brian W | McMaster University | Subvention de fonctionnement | Metabolic flexibility in obese youth: Exercise as a screening test and a treatment | Childhood Obesity; Clinical Care; Exercise; Glucose Metabolism |
| Tonelli, Marcello | University of Alberta | Subv. de fonctionnement -AP: Institut des services et des politiques de la santé | Risk of adverse effects among elderly statin users | Adverse Effect; Diabetes; Elderly; Epidemiological Study; Hypertension; Kidney Disease; Statin |
| Tonelli, Marcello | University of Calgary | Subvention de fonctionnement | Cardiovascular risk among cancer survivors | Cancer; Chemotherapy; Epidemiological Study; Heart Disease; Stroke |
| Topisirovic, Ivan | Lady Davis Institute for Medical Research (Mtl) McGill University/Université McGill |
Subvention de fonctionnement | Identification and characterization of novel substrates of the mammalian target of rapamaycin complex 1 (mTORC1). | Cell Proliferation And Growth; Mammalian Target Of Rapamycin; Mass Spectrometry; Metabolism; Tumorigenesis |
| Toth, Cory C | Hotchkiss Brain Institute (University of Calgary) University of Calgary |
Subvention de fonctionnement | The Diabetic Brain resulting from Insulin Deficiency and loss of PI3K/Akt signaling | Cerebral Atrophy; Cognitive Decline; Diabetes; Insulin; White Matter Abnormalities |
| Toth, Ellen L | University of Alberta | Subv de fonct - AP : santé des Premières nations, des Inuits et/ou des Métis | Diabetes in pregnancy in Aboriginal women: a mixed-methods study in three provinces | Aboriginal; Community; Determinants Of Health; Diabetes In Pregnancy; Epidemiology; Ethnicity; Pregnancy; Qualitative |
| Tousignant, Pierre | Direction régionale de santé publique (CIUSSS - CSIM) | Partenariats pour l'amélioration du système de santé (PASS) | Mise en oeuvre d'un réseau intégré de prévention et de gestion du risque cardiométabolique en 1re ligne à Montréal | Chronic care model; Collaboration interorganisationnelle; Diabète; Hypertension artérielle; Interdisciplinarité; Maladies cardiométaboliques; Maladies chroniques; Réseau intégré de services; Services de première ligne; services de santé |
| Tremblay, André | Centre hospitalier universitaire Sainte-Justine Université de Montréal |
Subvention de fonctionnement | Role of Ghrelin Signaling on Peripheral Nuclear Receptors and the Regulation of Lipid and Energy Metabolism | Adipocytes; Fatty Acid Metabolism; Ghrelin; Obesity; Ppar Nuclear Receptors; Thiazolidinediones |
| Tremblay, André | Université de Montréal | Subvention Projet | Peripheral regulation of PPAR Nuclear Receptors in energy metabolism | Cd36 Scavenger Receptor; Lipid Metabolism; Metabolic Disorders; Mitochondria; Ppar Nuclear Receptors |
| Seda, Ondrej | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention de fonct : prog de rech en collab avec l'industrie - Autre partenaire | Telomere attrition rate as predictor of cardiovascular complications of type 2 diabetes | Cardiovascular Disease; Diabetes Mellitus; Longitudinal Study; Telomere Length |
| Tremblay, Michel L | McGill University/Université McGill | Subvention de fonctionnement | PTP1b as a target in human cancer | Cancer Therapies; Oncogene; Receptor Trafficking; Tissue Micro Array; Transgenic Animal Models; Tyrosine Phosphatase |
| Tsuji, Leonard J | University of Waterloo (Ontario) | Subv. de fonctionnement - Recherche interv en santé des Autochtones-dem dét. | Fostering Adaptive Capacity and Resilience to Climate Change in Sub-Arctic First Nations: Addressing Food Security and Health Issues through Agroforestry Stewardship Practices | Adaptation; Agroforestry; Climate Change; First Nations; Food Security; Home Gardens; Nutrition; Obesity; Sub-Arctic; Sustainability |
| Tu, Karen | Institute for Clinical Evaluative Sciences-Toronto University of Toronto |
Subvention de fonctionnement | Feedback GAP: a trial of Goal-setting and Action-Plans to increase the effectiveness of audit and feedback interventions in primary care. | Audit and Feedback; Cardiovascular Risk; Cluster Randomized Trial; Diabetes; Electronic Medical Records; Ischemic Heart Disease; Knowledge Translation; Mixed Methods; Primary Care; Quality Of Care |
| Tupling, Allan R | University of Waterloo (Ontario) | Subvention de fonctionnement | The Role of Sarcolipin in Thermogenesis, Diet-induced Obesity and Glucose Intolerance | Ca2+ Pump; Indirect Calorimetry; Insulin Secretion; Metabolic Rate; Muscle Glucose Uptake; Sarcolipin; Skeletal Muscle; Transgenic Mouse |
| Ungrin, Mark D | University of Calgary | Subvention de fonctionnement | Optimizing the size and composition of beta cell aggregates to improve islet graft survival | Cell Survival; Controlled Cellular Aggregation; Extracellular Matrix; Islet Transplantation; Metabolic Transport Processes; Mixed Cellular Aggregates; Oxygenation; Retention Of Function; Size Control; Surface:Volume Ratio |
| Unniappan, Suraj | University of Saskatchewan | Subvention de fonctionnement | Neuroendocrine Regulation of Energy Homeostasis | Diabetes; Energy Balance; Glucose Homeostasis; Metabolism; Obesity; Pancreas |
| Unniappan, Suraj | University of Saskatchewan | Subvention de fonctionnement | Nesfatin-1 Regulation of Glucose and Energy Homesotasis | Beta Cells; Blood Glucose; Body Weight; Food Intake; Gastrointestinal Tract; Gluconeogenesis; Insulin; Liver; Metabolism; Pancreatic Islets |
| Urowitz, Murray B | University Health Network (Toronto) University of Toronto |
Subvention de fonctionnement | The Metabolic Syndrome in Patients with Systemic Lupus Erythematosus (SLE): Clinical, Therapeutic and Genetic Determinants in an International Inception Cohort Registry | Atherosclerotic Risk; Biomarkers; Genetics; Longitudinal Cohort; Metabolic Syndrome; Systemic Lupus |
| Ussher, John Edward R | University of Alberta | Subvention Projet | The GLP-1 Receptor & Myocardial Glucose Oxidation | Glucagon-Like Peptide-1; Glucagon-Like Peptide-1 Receptor; Glucose Oxidation; Liraglutide; Type 2 Diabetes |
| van der Kooy, Derek J | University of Toronto | Subvention Fondation | Cell lineage and neural development | Asymmetric Cell Division; Brain Development; Cell Reprogramming; Neural Stem Cells; Neurobiology Of Motivation; Pancreatic Stem Cells; Retinal Stem Cells |
| Vanasse, Alain | Université de Sherbrooke | Subv de fonct : prévention des maladies cardiovasculaires et respiratoires | Inégalités sociales et géographiques dans la prévention primaire des maladies cardiovasculaires et cérébrovasculaires | Facteurs de risque; Géomatique de la santé; Inégalités; Maladies cardiovasculaires; Santé des populations; Système d'information Spatio-Temporel |
| Vance, Dennis E | University of Alberta | Subvention de fonctionnement | Phosphatidylcholine and Metabolic Disorders | Adeno-Associated Virus; Diabetes; Obesity; Phosphatidylcholine; Phospholipid Methylation; Vagotomy |
| Vasconcelos, Sara N | University Health Network (Toronto) University of Toronto |
Sub de fonctionnement - AP : ISCR nouveaux chercheurs (financement transitoire) | Arterial-venous specification during adult neovascularization | Angiogenesis; Arterial-Venous Specification; Intravital Epifluorescence Videomicroscope; Neovascularization; Perivascular Cells; Regenerative Medicine; Skin Fold Window Chamber; Transgenic Mice; Vascular Biology; Vessel Remodeling |
| Vaucher, Elvire | Université de Montréal | Subvention de fonctionnement | Vascular inflammation in the diabetic retina: involvement of kinin B1 Receptor | Diabetic Retinopathy; Endothelial Dysfunction; Kinin; Microangiopathy; Microcirculation; Ocular Blood Flow; Retina; Type 1 Diabetes; Type 2 Diabetes; Vascular Inflammation |
| Veilleux, Alain | Inst. on Nutraceuticals & Functional Foods (QC) | Subvention de fonctionnement | Role of intestinal microenvironment and insulin resistance in postprandial dyslipidemia in humans | Cardiovascular Disease; Cellular Biology; Classical Lipidology And Lipidomics; Insulin Resistance; Lipid Tracer Assay; Obesity And Diabetes; Protein; Rna; Small Intestine |
| Venkateswaran, Vasundara | Sunnybrook Research Institute (Toronto, Ontario)University of Toronto | Subv de fonct - AP : fonds de démarrage de l'INMD (financement provisoire) | Utilizing metformin to enhance the efficacy of androgen deprivation therapy in prostate cancer | Bicalutamide; Insulin/Igf Signaling; Ionizing Radiation; Metformin; Obesity; Prostate Cancer Treatment |
| Venkateswaran, Vasundara | Sunnybrook Research Institute (Toronto, Ontario) University of Toronto |
Subvention de fonctionnement | Metformin: A radio- and chemo- sensitizer in prostate cancer | Castrate Resistant Prostate Cancer; Docetaxel; Hyperinsulinemia; Insulin/Igf Signaling; Ionizing Radiation; Metformin; Obesity; Prostate Cancer; Prostate Cancer Stem Cells; Xenograft |
| Verchere, Bruce C | BC Children's Hospital Research Institute University of British Columbia |
Subvention de fonctionnement | Amyloid-induced islet inflammation and beta cell dysfunction | Amylin; Beta Cell; Diabetes; Iapp; Inflammasome; Innate Immunity; Islet; Islet Amyloid; Islet Inflammation; Toll-Like Receptors |
| Ehses, Jan A | University of British Columbia | Subvention de fonctionnement | Regulatory macrophages in islet inflammation and type 2 diabetes | Diabetes; Inflammation; Insulin; Islets Of Langerhans; Macrophages; Pancreatic Beta Cell |
| Verchere, Bruce C | BC Children's Hospital Research InstituteUniversity of British Columbia | Subvention Projet | Islet macrophages: regulators of beta cell function in health and diabetes | Amyloid; Beta Cell; Diabetes; Iapp; Inflammasome; Insulin; Islet; Macrophage |
| Verchere, Bruce C | BC Children's Hospital Research Institute University of British Columbia |
Subvention de fonctionnement | Processing of proIAPP: Role in islet amyloid formation | Amylin; Amyloid; Beta Cell; Cell Biology; Histology; Iapp |
| Verchere, Bruce C | University of British Columbia | Subvention Projet | Genetic and acquired defects in islet prohormone processing in diabetes | Beta Cell; Biomarkers; Diabetes; Insulin; Islet Amyloid Polypeptide; Islet Biology; Post-Translational Modification; Prohormone; Prohormone Processing; Proinsulin |
| Verchere, Bruce C | BC Children's Hospital Research Institute University of British Columbia |
Subvention Projet | Islet macrophages: regulators of beta cell function in health and diabetes | Amyloid; Beta Cell; Diabetes; Iapp; Inflammasome; Inflammation; Innate Immunity; Insulin; Islet; Macrophage |
| Verma, Subodh S | St. Michael's Hospital (Toronto) University of Toronto |
Subv. de fonctionnement: Subv. pluriannuelle : essais clin. novateurs de la SRAP | Reducing Diabetic Foot Complications through a Multidisciplinary Chiropodist Based Intervention | Chiropodist-Led Care; Diabetes; Foot Ulcer; Peripheral Arterial Disease; Pragmatic Trial Design |
| Vine, Donna | University of Alberta | Subvention de fonctionnement | Dietary Fish Oil: A Treatment for Hyperlipidemia in Young Women with Polycystic Ovary Syndrome | Apob Triglyceride-Rich Lipoprotein Kinetics; Apob-Lipoprotein Remnants; Cardiometabolic Risk Factors; Cardiovascular Disease Risk; Dietary Intervention; Fasting And Non-Fasting Postprandial Lipid Metabolism; Metformin; N-3 Polyunsaturated Fatty Acid (Fish Oil); Polycystic Ovary Syndrome; Randomized Parallel Intervention |
| Vohl, Marie-Claude | Université Laval | Subvention de fonctionnement | A study of genetic and epigenetic factors influencing obesity-related metabolic complications. | Association Studies; Changes; Genetic; Metabolic Complications; Obesity; Transcriptional |
| Walker, Jennifer | University of Toronto | Subvention de fonctionnement | Unlocking Health Information for Older First Nations Populations | Administrative Data; Chronic Disease; First Nations; Frailty; Indigenous Health; Multimorbidity |
| Wang, Rennian | University of Western Ontario | Subvention Projet | Studies of the functional role of pancreatic stellate cells (PaSCs) during islet differentiation, regeneration and diabetes. | Diabetic Mouse Models; Human Fetal Pancreas; Islet Cell Differentiation; Islet Regeneration; Islet-Epithelial Cell Cluster Coculture; Pancreatic Duct Ligation; Pancreatic Stellate Cells; Pancreatic Stellate Cells Inhibitor |
| Wang, Rennian | University of Western Ontario | Subvention de fonctionnement | Analysis of c-Kit and insulin receptor signaling interactions in regulating pancreatic beta-cell function and islet vasculature | Beta-Cell Specific C-Kit Transgenic Mice; C-Kit Wv Mutation Mice; Cross-Talk Between C-Kit And Insulin Receptors; High-Fat Diet Diabetes; Insulin Receptor/Insulin Receptor Substrates; Islet Biology; Islet Vasculature; Pi3k/Akt/Gsk3b Signaling Pathway; Stem Cell Factor/C-Kit Recptor; Vegf Expression |
| Wassmann, Sven | Lady Davis Institute for Medical Research (Mtl) McGill University/Université McGill |
Subvention de fonctionnement | Role of AT1 receptor activation in progenitor cell biology, endothelial regeneration, atherosclerosis, insulin resistance, and adipogenesis | Atherosclerosis; Endothelial Progenitor Cells; Endothelial Regeneration / Function; Immunohistochemistry/Facs/Cell Culture; Insulin Sensitivity; Knockout Mice / Bone Marrow Transplantations |
| Welsh, Donald G | University of Calgary | Subvention de fonctionnement | Electrical and Second Messenger Communication in Resistance Arteries | Gap Junctions; Ion Channels; Smooth Muscle Physiology; Vascular Communication |
| Werstuck, Geoffrey H | McMaster University | Subvention de fonctionnement | The Role of the Hexosamine Biosynthesis Pathway in Diabetes-Induced Accelerated Atherosclerosis | Atherosclerosis; Diabetes Mellitus; Endoplasmic Reticulum Stress; Glutamine:Fructose-6 Phosphate Amidotransferase; Mouse Models |
| Werstuck, Geoffrey H | McMaster University | Subvention de fonctionnement | The Role of the Hexosamine Biosynthesis Pathway in Diabetes-Induced Accelerated Atherosclerosis | Atherosclerosis; Diabetes Mellitus; Endoplasmic Reticulum Stress; Glutamine:Fructose-6 Phosphate Amidotransferase; Mouse Models |
| Werstuck, Geoffrey H | McMaster University | Subvention de fonctionnement | Mechanisms by which Diabetes Mellitus promotes the development and progression of atherosclerosis | Atherosclerosis; Diabetes Mellitus; Endoplasmic Reticulum Stress; Glutamine:Fructose-6 Phosphate Amidotransferase; Mouse Models |
| Wheeler, Michael B | University of Toronto | Subvention de fonctionnement | Beta cell-stimulus secretion coupling: The role of zinc transport and its link to type 2 diabetes. | Beta Cell; Glucagon Secretion; Insulin Secretion; Type 2 Diabetes; Zinc Transporter Mutations And Diabetes Risk; Znt8 Transporter Function |
| Wheeler, Michael B | University of Toronto | Subvention de fonctionnement | Islet cell stimulus-secretion coupling: The role of mitochondrial uncouplers | Beta Cell Metabolism; Beta Cell Uncoupling Proteins; Insulin Secretion; Islet Cell Death; Obesity; Type 2 Diabetes |
| Wheeler, Michael B | University of Toronto | Subvention de fonctionnement | Mechanisms linking beta cell dysfunction to type 2 diabetes | Biomarkers; Diabetes; Gestational Diabetes; Insulin Secretion; Metabolomics; Pancreatic Beta Cell |
| Whitlock, Richard | McMaster University | Subv. fonct - AP : appareil locomoteur, arthrite, peau et santé buccodentaire | Transcutaneous oximetry, transcutaneous carbon dioxide and supplemental oxygen therapy in lower limb amputations - An observational study | Diabetes; Lower Limb Amputations; Observational Cohort Study; Orthopaedic Surgery; Supplemental Oxygen Therapy; Transcutaneous Carbon Dioxide; Transcutaneous Oximetry; Vascular Complications; Vascular Surgery; Wound Healing |
| Willing, Benjamin P | University of Alberta | Subv. de fonct. - AP : santé reproductive et infantile (subvent. de démarrage) | Programming effects of neonatal antibiotics on metabolic outcomes | Antibiotics; Beta Cell; Diabetes; Epigenetics; Immunity; Infant; Metabolic Disease; Microbiota; Obesity |
| Winer, Daniel A | University Health Network (Toronto) University of Toronto |
Subvention de fonctionnement | Mechanisms of B cell Pathogenicity in Insulin Resistance | Adaptive Immune System; Antibodies; Antigen Specificity; B Cells; Innate Immune System; Insulin; Insulin Resistance; Metabolic Syndrome; Obesity; Type 2 Diabetes |
| Winer, Daniel A | University Health Network (Toronto) University of Toronto |
Subvention Fondation | The role of the immune system in obesity related insulin resistance and metabolic disease | Adaptive Immune System; B Cells; Fatty Liver Disease; Immunometabolism; Innate Immune System; Insulin Resistance; Metabolic Syndrome; Obesity; T Cells; Type 2 Diabetes |
| Winer, Daniel A | University Health Network (Toronto) University of Toronto |
Subvention de fonctionnement | Defining Adaptive Immune Mechanisms of Insulin Resistance | Adaptive Immune System; Antibodies; Apoptosis; B Cells; Innate Immune System; Insulin Resistance; Metabolic Syndrome; Obesity; Type 2 Diabetes |
| Wishart, David S | University of Alberta | Subvention Fondation | New Resources for Chemical Genomics and Metabolomics in Biomedicine | Bioinformatics; Chemical Genomics; Chemical Libraries; Databases; Disease Biomarkers; Metabolomics; Pathways; Software Development |
| Wolever, Thomas M | University of Toronto | Subvention de fonctionnement | Role of colonic short chain fatty acids in obesity and insulin resistance | Colonic Fermentation; Gut Hormones; Humans; Insulin Sensitivity; Obesity; Whole Body Metabolism |
| Wolever, Thomas M | University of Toronto | Subvention de fonctionnement | The effect of a low glycemic index (GI) diet on maternal glycemic control and maternal and neonatal markers of postpartum diabetes risk in women with gestational hyperglycemia | Clinical Trial; Dietary Carbohydrates; Gestational Diabetes; Glycemic Control; Glycemic Index; Humans |
| Woo, Minna N | University Health Network (Toronto) University of Toronto |
Subvention de fonctionnement | Dissecting inflammatory and apoptotic signaling in adipocytes | Apoptosis; Caspase; Cre-Lox P; Diabetes; High Fat Diet; Inflammasome; Inflammation; Insulin Resistance; Knockout Mice; Obesity |
| Woo, Minna N | University Health Network (Toronto) University of Toronto |
Subvention de fonctionnement | Hypothalamic regulation of adipocytes and peripheral insulin sensitivity | Adipocyte; Cre-Loxp; High Fat Diet; Insulin Resistance; Knockout Mice; Obesity |
| Woo, Minna N | University Health Network (Toronto) University of Toronto |
Subvention de fonctionnement | Genetic Determinants of Pancreatic Beta Cell Homeostasis | Cre Lox P; Diabetes; Epo Signaling; Erythropoietin; Knockout Mice; Pancreatic Beta Cells |
| Woodgett, James (Jim) R | Lunenfeld-Tanenbaum Research Institute (Toronto) University of Toronto |
Subvention Fondation | Genetic analysis of signal transduction pathways involved in human diseases | Cell Regulation; Diabetes; Metabolism; Oncogene; Protein Kinase; Signal Transduction; Stem Cell; Transgenic Mouse |
| Woolcott, Christy G | IWK Health Centre (Halifax) Dalhousie University (Nova Scotia) |
Subv de fonct. - AP : Programme de partenariats régionaux - Nouvelle Ecosse | Pregnancy characteristics and maternal long term weight-related outcomes: a cohort study | Adipokines; Biological Mediators; Cardiovascular Disease; Chronic Disease Risk; Diabetes; Epidemiology; Life Course Health; Obesity; Pregnancy; Women's Health |
| Woolcott, Christy G | IWK Health Centre (Halifax) Dalhousie University (Nova Scotia) |
Subvention de fonctionnement | Do pregnancy characteristics help to predict the future risk of maternal cardiovascular outcomes? A population-based longitudinal cohort study | Cardiovascular Disease; Cohort; Diabetes; Epidemiology; Hypertension; Pregnancy; Risk Prediction; Women'S Health |
| Wright, David | University of Guelph | Subv de fonct - AP : fonds de démarrage de l'INMD (financement provisoire) | Regulation of Adipose Tissue Metabolism | Adipose; Exercise; Fasting; Gene Expression; Knockout Mice; Mitochondria; Rat; Re-Esterification; Signaling; Tissue Culture |
| Wright, David | University of Guelph | Subvention de fonctionnement | Novel Effects of Exercise on Adipose Tissue Insulin Action | Adipose; Exercise; Glycogen; Insulin; Knockout Mice; Lipolysis; Liver; Obesity; Signaling; Skeletal Muscle |
| Wu, Lingyun (Lily) | University of Saskatchewan | IRSC/ Programme de partenariats régionaux/Subvention de fonctionnement | Mechanisms and intervention for methyglyoxal-induced glycation of AKT1 | Akt1; Methylglyoxal And Ages; Proliferation; Smg08; Smooth Muscle Cells; Vascular Remodeling |
| Yang, Kaiping | University of Western Ontario | Subvention de fonctionnement | Early-life origins of visceral adiposity | Adipose Tissue Growth And Development; Cellular And Molecular Mechanisms; Early-Life Progamming; Knockout Mouse Models; Maternal Protein Restriction; Visceral Adiposity |
| Yao, Zemin | University of Ottawa/Université d'Ottawa | Subvention de fonctionnement | New lipid and protein factors regulating hepatic TAG homeostasis | Apociii; Er Stress; Hepatosteatosis; Lumenal Lipid Droplets; Proteomics; Systems Biology; Triacylglycerol; Vldl Overproduction |
| Yu, Catherine | St. Michael's Hospital (Toronto) University of Toronto |
Subvention de fonctionnement : des connaissances à la pratique | Development, testing and feasibility of an interprofessional shared decision-making and goal-setting decision aid for patients with diabetes in clinical care | Decision Aid; Diabetes Mellitus; Guideline Adherence; Interprofessional Care; Knowledge Translation; Multimorbidity; Shared Decision-Making |
| Yu, Catherine | University of Toronto | Subvention de fonctionnement : des connaissances à la pratique | Effect of a web-based self-management intervention for patients with type 2 diabetes on clinical and psychological outcomes | Integrated Knowledge Translation; Patient Self-Management; Qualitative Methodology; Type 2 Diabetes; Web-Based Technology |
| Yue, Jessica T | University of Alberta | Subvention Projet | Lipid homeostasis regulation by brain glucagon signalling | Central Nervous System; Diabetes; Dorsal Vagal Complex; Glucagon; Lipid Metabolism; Liver; Mediobasal Hypothalamus; Obesity |
| Yuen, Darren A | St. Michael's Hospital (Toronto) University of Toronto |
Subvention Projet | Sweet and Stiff: How diabetes activates YAP and TAZ to trigger kidney fibrosis | Diabetes; Diabetic Nephropathy; Fibrosis; Rhoa; Taz; Yap |
| Yusuf, Salim | McMaster University | Subvention Fondation | Prospective Urban Rural Epidemiology (PURE) Program: causes, consequences, and impact of health systems for CVD and other NCDs | Cardiovascular Diseases; Environment And Health; Epidemiology; Global Health; Health Systems; Non-Communicable Diseases; Population Health; Risk Factors |
| Yusuf, Salim | McMaster University | Subvention de fonctionnement | INTERSTROKE: Importance of Conventional and Emerging Risk Factors for Stroke in Different Regions and Ethnic Groups of the World | Prevention; Risk Factors; Stroke |
| Zamponi, Gerald W | University of Calgary | Subvention Fondation | Voltage gated calcium channels: molecular targets for pain therapeutics | Calcium Channels; Diabetic Neuropathy; G Protein Coupled Receptors; Inflammatory Pain; Neuropathic Pain; Pain; Ubiquitination |
| Zeng, Haishan | B.C. Cancer Research Centre (Vancouver) University of British Columbia |
Subvention Projet | Multiphoton Photothermolysis Based Laser Therapy for Precision Treatment of Neovascular Eye Diseases | Biophotonics; Confocal Microscopy; Corneal Neovascularization; Diabetic Retinopathy; Eye Diseases; Laser Therapy; Macular Degeration; Multiphoton Microscopy; Multiphoton Photothermolysis; Ophthalmology |
| Zhai, Guangju | Memorial University of Newfoundland | Subv fonct -AP: IALA -nouveaux cher fin. transitoire -santé musculosquelettique | The link between osteoarthritis and diabetes mellitus | Advanced-Glycation End-Products; Diabetes Mellitus; Glucose Transporter 1; Metabolic Markers; Methylglyoxal; Osteoarthritis |
| Zhang, Shao-Ling | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention de fonctionnement | Maternal Diabetes, Reactive Oxygen Species, Nephrogenesis and Perinatal Programming | Hypertension; Intrarenal Angiotensin Converting Enzyme-2; Kidney Injury; Maternal Diabetes; Perinatal Programming; Reactive Oxygen Species (Ros); Renin-Angiotensin System |
| Zhang, Shao-Ling | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention Projet | Maternal Diabetes Induces Perinatal Programming of Hypertension and Chronic Kidney Disease: Role Of Hedgehog Interacting Protein (Hhip) | Chronic Kidney Disease; Hedgehog Interacting Protein; Hypertension; Maternal Diabetes; Perinatal Programming; Transgenic And Knockout Mouse Models |
| Zhang, Shao-Ling | Centre hospitalier de l'Université de Montréal (CHUM) Université de Montréal |
Subvention de fonctionnement | Maternal Diabetes and Perinatal Programming: Role of Reactive Oxygen Species | Hypertension; Intrarenal Angiotensin Converting Enzyme-2; Kidney Injury; Maternal Diabetes; Perinatal Programming; Reactive Oxygen Species (Ros); Renin-Angiotensin System |
| Zochodne, Douglas W | University of Calgary | Subvention de fonctionnement | Rescue of diabetic sensory neurodegeneration through insulin signaling | Diabetic Polyneuropathy; Experimental Diabetes; Insulin; Neurodegeneration; Sensory Neurons |
| Zuniga-Pflucker, Juan C | Sunnybrook Research Institute (Toronto, Ontario) University of Toronto |
Subvention de fonctionnement | Characterization and lineage commitment of progenitor thymocytes | Delta-Like; Eva1; Immune Reconstitution; Lymphocyte Development; Lymphocyte Progenitors; Notch Signaling; Stromal Cells; T Cell Development; Thymus; Thymus Epithelial Cells |
| Zuniga-Pflucker, Juan C | Sunnybrook Research Institute (Toronto, Ontario) University of Toronto |
Subv. de fonct - AP : maladies infectieuses & immunitaires (fin provisoire) | Characterization and lineage commitment of progenitor thymocytes | Delta-Like; Eva1; Immune Reconstitution; Lymphocyte Development; Lymphocyte Progenitors; Notch Signaling; Stromal Cells; T Cell Development; Thymus; Thymus Epithelial Cells |
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