Pre-announcement – Team Grants: Diabetes Mechanisms and Translational Solutions

The funding opportunity is now available on ResearchNet (Application deadline : November 18, 2020)

The CIHR Institute of Nutrition, Metabolism and Diabetes, Institute of Genetics, Institute of Infection and Immunity and Institute of Indigenous Peoples’ Health, along with the Institute of Aging, Institute of Circulatory and Respiratory Health, Institute of Gender and Health and Institute of Musculoskeletal Health and Arthritis, in partnership with Diabetes Canada, Fonds de recherche du Québec–Santé (FRQS), JDRF Canada, Kidney Foundation of Canada (KFOC) and Mitacs are pleased to announce the upcoming funding opportunity for Team Grants: Diabetes Mechanisms and Translational Solutions.

In 2021, Canada will celebrate the 100th anniversary of the discovery of insulin, for which Drs. Banting and McLeod received a Nobel Prize- an illustrious moment for Canadians and one of the most dramatic examples of rapid translation of a discovery in basic science into a benefit for patients. Millions of lives have been saved due to this discovery, yet the prevalence of diabetes continues to increase and diabetes remains a chronic disease.

The Team Grants in Diabetes Mechanisms and Translational Solutions will support multi-disciplinary research to better understand the underlying causes and pathophysiology of diabetes, and develop improved prevention and treatment approaches for diabetes.

Objectives

The objectives of the Team Grants in Diabetes Mechanisms and Translational Solutions are:

  1. To elucidate previously undefined mechanisms that control the onset and progression of all types of diabetes mellitus and related complications and co-morbidities, with appropriate consideration of sex as a biological variable and gender as a social determinant of health.
  2. To develop new translational solutions aimed at prevention, treatment, and delivery of care for people living with diabetes.

Mechanistic research is defined as research to understand the pathophysiology of diabetes, complications and co-morbidities. Translational research encompasses research that advances effective translation and application of knowledge across the expanse of pre-clinical, clinical and health services delivery domains to improve patient outcomes. The scope of these grants will be inclusive of both mechanistic studies, and translational studies, but there will not be a requirement that all applications will include both mechanistic and translational research.

Eligibility

In addition to the Nominated Principal Applicant, research teams must be comprised of no more than 4 Principal Applicants, one of whom is identified as a Sex and Gender Champion, and research teams must be based in more than 1 province. The research team must include an Early Career Researcher and must engage patients/people affected by diabetes representative of the populations being studied in a manner appropriate for the research being proposed.

Funds available

CIHR and partner financial contributions for this initiative are subject to availability of funds. Should funding levels not be available or are decreased due to unforeseen circumstances, CIHR and its partners reserve the right to reduce, defer or suspend financial contributions to grants received as a result of this funding opportunity.

The total amount available for this funding opportunity is $20,200,000. The total amount available at the LOI stage is $200,000, enough to fund approximately 20 LOIs ($10,000 each). At the full application stage, a total of $20,000,000 is available, enough to fund up to 10 grants. The maximum amount per grant is $400,000 per year for up to 5 years, for a total of $2,000,000 per grant.

Additional funding is available through Mitacs to fund internships for graduate students and post-doctoral fellows in funded Team Grants.

Anticipated timelines*:
Date
Launch Date Early winter 2020
LOI Deadline Spring 2020
Full Application Deadline Late Fall 2020
Notice of Decision Late March 2021
Funding Start Date April 1, 2021

*These timelines are estimates and subject to change.

For all inquiries please contact:

CIHR Contact Centre
Telephone: 613-954-1968
Toll Free: 1-888-603-4178
Email: support-soutien@cihr-irsc.gc.ca

Disclaimer: The information contained in this pre-announcement of the Team Grants: Diabetes Mechanisms and Translational Solutions funding opportunity is subject to change and does not commit CIHR or partners to the requirements outlined in this version. The final funding opportunity will be published by CIHR in the Funding Opportunity Database in ResearchNet in the early winter 2020.

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